TFAP2A

protein-coding gene in the species Homo sapiens
Gene gene Q18031952
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Summary

TFAP2A is a gene[1]. TFAP2A ranks in the top 2% of gene entities by monthly Wikipedia readership (95 views/month).[2]

Key Facts

  • Subclass of: protein-coding gene[3]
  • HomoloGene ID: 2421[4]
  • Genomic start: 10393186[5], 10393419[6]
  • Genomic end: 10419659[7], 10419892[8]
  • Ortholog: Tfap2a[9], TfAP-2[10]
  • Encodes: Transcription factor AP-2 alpha[11], Transcription factor AP-2 alpha (Activating enhancer binding protein 2 alpha), isoform CRA_c[12], Transcription factor AP-2-alpha[13]
  • Found in taxon: Homo sapiens[14]
  • Chromosome: human chromosome 6[15]
  • Genetic association: amyotrophic lateral sclerosis[16], branchiooculofacial syndrome[17]
  • Strand orientation: reverse strand[18]
  • Exact match: http://identifiers.org/ncbigene/7020[19]
  • Cytogenetic location: 6p24.3[20]
  • Expressed in: skin of thigh[21], gingival epithelium[22], skin of arm[23], vulva[24], skin of hip[25], skin of abdomen[26], hair follicle[27], epithelium of lactiferous gland[28], lactiferous duct[29], nipple[30]

Why It Matters

TFAP2A is known by 7 alternative names across languages and contexts.[31]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . Ensembl Release 87. wikidata.org.
  2. [4] ↑ . NCBI Gene. Retrieved . wikidata.org.
  3. [5] ↑ . ensembl Release 106. wikidata.org.
  4. [6] ↑ . ensembl Release 106. wikidata.org.
  5. [7] ↑ . ensembl Release 106. wikidata.org.
  6. [8] ↑ . ensembl Release 106. wikidata.org.
  7. [9] ↑ . HomoloGene build68. omabrowser.org. Provenance: wikidata.org.
  8. [10] ↑ . HomoloGene build68. wikidata.org.
  9. [11] ↑ . UniProt. Retrieved . wikidata.org.
  10. [12] ↑ . UniProt. Retrieved . wikidata.org.
  11. [13] ↑ . UniProt. Retrieved . wikidata.org.
  12. [14] ↑ . ensembl Release 106. wikidata.org.
  13. [15] ↑ . ensembl Release 106. wikidata.org.
  14. [16] ↑ . Phenocarta. Retrieved . gemma.msl.ubc.ca. Provenance: wikidata.org.
  15. [17] ↑ . UniProt. Retrieved . platform.opentargets.org. Provenance: wikidata.org.
  16. [18] ↑ . ensembl Release 106. wikidata.org.
  17. [19] ↑ . Identifiers.org. ebi.ac.uk. Provenance: wikidata.org.
  18. [20] ↑ . NCBI Gene. Retrieved . wikidata.org.
  19. [21] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  20. [22] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  21. [23] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  22. [24] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  23. [25] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  24. [26] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  25. [27] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  26. [28] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  27. [29] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  28. [30] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikimedia Foundation. dumps.wikimedia.org.
  2. [31] ↑ . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). TFAP2A. Retrieved October 26, 2026, from https://4ort.xyz/entity/tfap2a
MLA “TFAP2A.” 4ort.xyz Knowledge Graph, 4ort.xyz, 26 Oct. 2026, https://4ort.xyz/entity/tfap2a.
BibTeX @misc{4ortxyz_tfap2a_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{TFAP2A}}, year = {2026}, url = {https://4ort.xyz/entity/tfap2a}, note = {Accessed: 2026-10-26}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): TFAP2A — https://4ort.xyz/entity/tfap2a (retrieved 2026-10-26)

Canonical URL: https://4ort.xyz/entity/tfap2a · Last refreshed:

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 22w ago · Mathieu Kappler · 2026-05-20 view diff on Wikidata ↗
    Hgnc gene symbol → TFAP2A
    Genetic association → amyotrophic lateral sclerosis, branchiooculofacial syndrome
    Refseq rna id → NM_001032280, NM_001042425, NM_003220 +1
    Microsoft academic id (discontinued) → 2778222033
    + 23 other properties edited (see Wikidata diff for full list)
    "/* wbeditentity-update-languages-short:0||gsw */ QuickStatements 3.0 [[:toollabs:qs-dev/batch/32527|batch #32527]]: human gene name and description in Alemannic"
Live feed via Wikidata EventStreams. New edits appear within minutes of being made on Wikidata.