Nicastrin
mammalian protein found in Homo sapiens
Facts
8 properties- Instance of
- protein
- Part of
- Nicastrin[5]
- Biological process
- Notch signaling pathway, ephrin receptor signaling pathway, myeloid cell homeostasis, protein processing, positive regulation of catalytic activity, amyloid-beta metabolic process, epithelial cell proliferation, proteolysis, T cell proliferation, membrane protein ectodomain proteolysis, membrane protein intracellular domain proteolysis, positive regulation of apoptotic process, Notch receptor processing, amyloid precursor protein catabolic process, amyloid-beta formation, amyloid precursor protein metabolic process, neutrophil degranulation, Notch signaling pathway, Notch receptor processing, protein processing, cerebellum development, Notch receptor processing, ligand-dependent, membrane protein ectodomain proteolysis, dopamine receptor signaling pathway, glutamate receptor signaling pathway, learning or memory, protein processing, central nervous system myelination, adult behavior, amyloid precursor protein metabolic process, amyloid precursor protein biosynthetic process, positive regulation of amyloid precursor protein biosynthetic process, positive regulation of catalytic activity, neuron apoptotic process, neuron death, cellular response to calcium ion, regulation of long-term synaptic potentiation, short-term synaptic potentiation[23][24][25][26][27][28][29][30][31][32][33][34][35][36]
- Cell component
- Golgi apparatus, membrane, focal adhesion, melanosome, plasma membrane, integral component of plasma membrane, lysosomal membrane, endoplasmic reticulum, extracellular exosome, integral component of membrane, azurophil granule membrane, gamma-secretase complex, cytoplasmic vesicle membrane, cytoplasmic vesicle, cytoplasm, mitochondrion, lysosome, lysosomal membrane, early endosome, integral component of plasma membrane, focal adhesion, synaptic vesicle, endosome membrane, membrane, protein-containing complex, sarcolemma, synapse, extracellular exosome, synaptic membrane, integral component of presynaptic membrane, endoplasmic reticulum, Golgi apparatus, integral component of plasma membrane[9][10][11][12][13][14][15][16][17][18][19][20][21][22]
- Encoded by
- NCSTN
- Found in taxon
- Homo sapiens
- Molecular function
- peptidase activity, protein binding, endopeptidase activity[6][7][8]
🏷️ Also known as
en anterior pharynx-defective 2
en NCSTN
en nicastrin
en Nicastrin
en uniprot:Q92542
es Nicastrina
ja ニカストリン
🔖 Identifiers · 7
- OpenAlex ID
- C2779658117
- Ensembl protein ID
- ENSP00000294785, ENSP00000357042, ENSP00000388118, ENSP00000389370, ENSP00000390409, ENSP00000407849, ENSP00000410124, ENSP00000415442, ENSP00000493689, ENSP00000495179
- Freebase ID
- /m/02kffyt
- Microsoft Academic ID (discontinued)
- 2779658117
- RefSeq protein ID
- NP_001277113, NP_001277115, NP_056146, XP_005245110, NP_001336658
- UniProt protein ID
- Rainer Podlesch
🔗 Connections
Cell component 17
Biological process 3
Found in taxon 1
Instance of 1
Molecular function 1
UniProt protein ID 1
Press Enter · cited answer in seconds
0 sources
Summary
Nicastrin is a protein[1].