Crohn's disease

type of inflammatory bowel disease
MedicalCondition designated_intractable_rare_disease Q1472
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Summary

Crohn's disease is a designated intractable/rare disease[1]. It ranks in the top 7% of designated intractable rare disease entities by monthly Wikipedia readership (31,064 views/month).[2]

Key Facts

  • Instance of: rare disease[3], class of disease[4]
  • Named after: Burrill Bernard Crohn[5]
  • Subclass of: inflammatory bowel diseases[6], disease[7]
  • Commons category: Crohn's disease[8]
  • Symptoms and signs: diarrhea[9], weight loss[10], abdominal pain[11], fatigue[12]
  • Topic's main category: Category:Crohn's disease[13]
  • Medical examination: biopsy[14], medical imaging[15]
  • External data available at URL: http://www.nanbyou.or.jp/entry/81[16]
  • ICD-9-CM: 555.1[17]
  • NCI Thesaurus ID: C35211[18], C37262[19]
  • Health specialty: gastroenterology[20]
  • Drug or therapy used for treatment: ustekinumab[21], cholecalciferol[22], steroid[23], aminosalicylate[24], antibiotic[25], TNF inhibitor[26], immunosuppressive drug[27], targeted therapy[28]
  • Genetic association: IL23R[29], RUNX3[30], JAK2[31], STAT3[32], PSORS1C3[33], SP140[34], CPEB4[35], LACC1[36], IFNGR2[37], NOD2[38], ZMIZ1[39], SOCS1[40], CAPZB[41], ZDHHC23[42]

Why It Matters

Crohn's disease has Wikipedia articles in 29 language editions, a strong signal of global cultural recognition.[43] It is known by 63 alternative names across languages and contexts.[44]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . wikidata.org.
  2. [4] ↑ . wikidata.org.
  3. [5] ↑ . wikidata.org.
  4. [6] ↑ . Disease Ontology. Retrieved . wikidata.org.
  5. [7] ↑ . wikidata.org.
  6. [8] ↑ . wikidata.org.
  7. [9] ↑ . PubMed. wikidata.org.
  8. [10] ↑ . PubMed. wikidata.org.
  9. [11] ↑ . PubMed. wikidata.org.
  10. [12] ↑ . PubMed. wikidata.org.
  11. [13] ↑ . wikidata.org.
  12. [14] ↑ . wikidata.org.
  13. [15] ↑ . wikidata.org.
  14. [16] ↑ . ddrare.nibiohn.go.jp. Retrieved . ddrare.nibiohn.go.jp. Provenance: wikidata.org.
  15. [17] ↑ . Disease Ontology. Retrieved . wikidata.org.
  16. [18] ↑ . Disease Ontology. Retrieved . wikidata.org.
  17. [19] ↑ . Disease Ontology. Retrieved . wikidata.org.
  18. [20] ↑ . wikidata.org.
  19. [21] ↑ . ChEMBL. Retrieved . wikidata.org.
  20. [22] ↑ . NDF-RT. Retrieved . wikidata.org.
  21. [23] ↑ . wikidata.org.
  22. [24] ↑ . wikidata.org.
  23. [25] ↑ . wikidata.org.
  24. [26] ↑ . wikidata.org.
  25. [27] ↑ . wikidata.org.
  26. [28] ↑ . wikidata.org.
  27. [29] ↑ . Phenocarta. Retrieved . gemma.msl.ubc.ca. Provenance: wikidata.org.
  28. [30] ↑ . Phenocarta. Retrieved . gemma.msl.ubc.ca. Provenance: wikidata.org.
  29. [31] ↑ . Phenocarta. Retrieved . gemma.msl.ubc.ca. Provenance: wikidata.org.
  30. [32] ↑ . Phenocarta. Retrieved . gemma.msl.ubc.ca. Provenance: wikidata.org.
  31. [33] ↑ . Phenocarta. Retrieved . gemma.msl.ubc.ca. Provenance: wikidata.org.
  32. [34] ↑ . Phenocarta. Retrieved . gemma.msl.ubc.ca. Provenance: wikidata.org.
  33. [35] ↑ . Phenocarta. Retrieved . gemma.msl.ubc.ca. Provenance: wikidata.org.
  34. [36] ↑ . Phenocarta. Retrieved . gemma.msl.ubc.ca. Provenance: wikidata.org.
  35. [37] ↑ . Phenocarta. Retrieved . gemma.msl.ubc.ca. Provenance: wikidata.org.
  36. [38] ↑ . Phenocarta. Retrieved . gemma.msl.ubc.ca. Provenance: wikidata.org.
  37. [39] ↑ . Phenocarta. Retrieved . gemma.msl.ubc.ca. Provenance: wikidata.org.
  38. [40] ↑ . Phenocarta. Retrieved . gemma.msl.ubc.ca. Provenance: wikidata.org.
  39. [41] ↑ . Phenocarta. Retrieved . gemma.msl.ubc.ca. Provenance: wikidata.org.
  40. [42] ↑ . Phenocarta. Retrieved . gemma.msl.ubc.ca. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikimedia Foundation. dumps.wikimedia.org.
  2. [43] ↑ . Wikidata sitelinks. wikidata.org.
  3. [44] ↑ . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Crohn's disease. Retrieved October 15, 2026, from https://4ort.xyz/entity/crohn-s-disease
MLA “Crohn's disease.” 4ort.xyz Knowledge Graph, 4ort.xyz, 15 Oct. 2026, https://4ort.xyz/entity/crohn-s-disease.
BibTeX @misc{4ortxyz_crohn-s-disease_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Crohn's disease}}, year = {2026}, url = {https://4ort.xyz/entity/crohn-s-disease}, note = {Accessed: 2026-10-15}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Crohn's disease — https://4ort.xyz/entity/crohn-s-disease (retrieved 2026-10-15)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 15w ago · JhealdBatch bot · 2026-07-03 view diff on Wikidata ↗
    Subclass of → inflammatory bowel diseases, disease
    "/* wbeditentity-update:0| */ QuickStatements 3.0 [[:toollabs:qs-dev/batch/39732|batch #39732]]: rm redundant subclass"
  2. 17w ago · Yirba · 2026-06-19 view diff on Wikidata ↗
    P14541 → qjvkF
    "/* wbeditentity-update:0| */ QuickStatements 3.0 [[:toollabs:qs-dev/batch/37385|batch #37385]]: Encyclopedia of China (Third Edition) ID (2026) (P14541)"
  3. 18w ago · Jindřich Rubeš · 2026-06-12 view diff on Wikidata ↗
    Svkkl authority id → h0010063-Crohnova-nemoc
    "/* wbcreateclaim-create:1| */ Svkkl authority id: h0010063-Crohnova-nemoc, [[:toollabs:quickstatements/#/batch/259493|batch #259493]]"
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