methotrexate

chemical compound
ChemicalSubstance type_of_chemical_entity Q422232
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methotrexate

Summary

methotrexate is a type of chemical entity[1]. methotrexate ranks in the top 1% of type_of_chemical_entity entities by monthly Wikipedia readership (3,331 views/month).[2]

Key Facts

  • methotrexate's instance of is recorded as type of chemical entity[3].
  • methotrexate's physically interacts with is recorded as solute carrier family 46 member 1[4].
  • methotrexate's physically interacts with is recorded as solute carrier family 19 member 1[5].
  • methotrexate's manufacturer is recorded as Pfizer[6].
  • methotrexate's canonical SMILES is recorded as CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O[7].
  • methotrexate's chemical formula is recorded as C₂₀H₂₂N₈O₅[8].
  • methotrexate is a type of Amethopterin[9].
  • methotrexate is part of cellular response to methotrexate[10].
  • methotrexate is part of methotrexate transmembrane transporter activity[11].
  • methotrexate is part of response to methotrexate[12].
  • methotrexate is used for medication[13].
  • methotrexate's Commons category is recorded as Methotrexate[14].
  • methotrexate's route of administration is recorded as oral administration[15].
  • methotrexate's route of administration is recorded as intravenous infusion and defusionههبهلخل[16].
  • methotrexate's route of administration is recorded as intramuscular injection[17].
  • methotrexate's route of administration is recorded as intrathecal administration[18].

Why It Matters

methotrexate ranks in the top 1% of type_of_chemical_entity entities by monthly Wikipedia readership (3,331 views/month).[2] methotrexate has Wikipedia articles in 25 language editions, a strong signal of global cultural recognition.[19] methotrexate is known by 34 alternative names across languages and contexts.[20]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] . wikidata.org.
  2. [4] . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  3. [5] . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  4. [6] . pfizer.com. pfizer.com. Provenance: wikidata.org.
  5. [7] . PubChem. Retrieved . wikidata.org.
  6. [8] . PubChem. Retrieved . wikidata.org.
  7. [9] . wikidata.org.
  8. [10] . Gene Ontology release 2019-11-16. wikidata.org.
  9. [11] . Gene Ontology release 2019-11-16. wikidata.org.
  10. [12] . Gene Ontology release 2020-05-02. wikidata.org.
  11. [13] . wikidata.org.
  12. [14] . wikidata.org.
  13. [15] . wikidata.org.
  14. [16] . wikidata.org.
  15. [17] . wikidata.org.
  16. [18] . wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] . Wikimedia Foundation. dumps.wikimedia.org.
  2. [19] . Wikidata sitelinks. wikidata.org.
  3. [20] . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). methotrexate. Retrieved May 3, 2026, from https://4ort.xyz/entity/methotrexate
MLA “methotrexate.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/methotrexate.
BibTeX @misc{4ortxyz_methotrexate_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{methotrexate}}, year = {2026}, url = {https://4ort.xyz/entity/methotrexate}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): methotrexate — https://4ort.xyz/entity/methotrexate (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/methotrexate · Last refreshed:

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 1d ago · Twofivesixbot bot · 2026-05-25 view diff on Wikidata ↗
    Subclass of Amethopterin
    Found in taxon Gambierdiscus, Asimina triloba, Quambalaria cyanescens +1
    Route of administration oral administration, intravenous infusion and defusionههبهلخل, intramuscular injection +1
    Has use medication
    + 18 other properties edited (see Wikidata diff for full list)
    "/* wbsetclaim-update-qualifiers:1||1|3 */ [[Property:P8189]]: 987007529313305171, mv to monolingual text names on J9U statements"
Live feed via Wikidata EventStreams. New edits appear within minutes of being made on Wikidata.