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tromethamine

chemical compound
Class type of: chemical compound Q413961

Facts

10 properties
Instance of
type of chemical entity
Subclass of
chemical compound[4]
Has use
medication[5]
Canonical SMILES
C(C(CO)(CO)N)O[2]
Chemical formula
C₄H₁₁NO₃[3]
Has part(s)
nitrogen, oxygen, carbon[6][7][8]
Mass
+121.073893[9]
Melting point
+172[10]
Safety classification and labelling
NFPA 704: Standard System for the Identification of the Hazards of Materials for Emergency Response[13]
World Health Organisation international non-proprietary name
trometamol, trometamolum[11][12]
🏷️ Also known as
en trometamol en Tromethamine en tromethamine en Trometamol en 1,1,1-tris(hydroxymethyl)methanamine en 2-Amino-2-(hydroxymethyl)-1,3-propanediol en aminotris(hydroxymethyl)methane en THAM en tris en Tris en Tris amino en Tris base en Tris-base en Tris buffer en tris(hydroxymethyl)aminomethane en Tris(hydroxymethyl)aminomethane ar تريس cs trometamol de Trometamol de TRIS-Puffer
🔖 Identifiers · 42
OpenAlex ID
C2781014771
CAS Registry Number
77-86-1
ChEBI ID
9754
ChEMBL ID
CHEMBL1200391
ChemSpider ID
6257
CosIng number
80438
DSSTOX compound identifier
DTXCID503723
DSSTox substance ID
DTXSID2023723
DrugBank ID
DB03754
DrugCentral ID
2771
EC number
201-064-4
ECHA Substance Infocard ID
100.000.969
Show all 42 identifiers +30
Freebase ID
/m/02hd7f
Gmelin number
217857
Guide to Pharmacology Ligand ID
7328
HSDB ID
3408
Human Metabolome Database ID
HMDB0240288
InChI
InChI=1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2
InChIKey
LENZDBCJOHFCAS-UHFFFAOYSA-N
KEGG ID
D00396, C07182
MassBank accession ID
MSBNK-Keio_Univ-KO002368, MSBNK-Keio_Univ-KO002369, MSBNK-Keio_Univ-KO002370, MSBNK-Keio_Univ-KO002371, MSBNK-Keio_Univ-KO002372
MeSH descriptor ID
D014325
MeSH tree code
D02.033.455.706.900
Microsoft Academic ID (discontinued)
2781014771
NDF-RT ID
N0000146434
NMRShiftDB structure ID
10024064
NSC number
6365, 65434
Nikkaji ID
J4.214E
PesticideInfo chemical ID
PRI6461
Probes And Drugs ID
PD002520
PubChem CID
6503
RTECS number
TY2900000
Reaxys registry number
741883
RxNorm CUI
10865
SPLASH
splash10-0pi0-7900000000-244b89c0e2e656701b1d, splash10-0a4i-9000000000-a468801012da982d3bac, splash10-0a4i-9000000000-eb66f99d48d2027e0fb2, splash10-0a4i-9000000000-2983a91b4350760fab44
SureChEMBL ID
975
UMLS CUI
C0041175
UNII
023C2WHX2V
UniChem compound ID
117341
WikiProjectMed ID
Tris
World Health Organisation international non-proprietary name numeric ID
1108
ZVG number
100571

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🔗 Connections
Has part(s) 3
oxygen, carbon, nitrogen
Belongs to 2
aloglutamol, TE buffer
Has use 1
medication
Subclass of 1
chemical compound
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Summary

tromethamine is a type of chemical entity[1].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] ↑ . PubChem. Retrieved . wikidata.org.
  2. [3] ↑ . PubChem. Retrieved . wikidata.org.
  3. [4] ↑ . wikidata.org.
  4. [5] ↑ . wikidata.org.
  5. [6] ↑ . wikidata.org.
  6. [7] ↑ . wikidata.org.
  7. [8] ↑ . wikidata.org.
  8. [9] ↑ . PubChem. Retrieved . wikidata.org.
  9. [10] ↑ . Jean-Claude Bradley Open Melting Point Dataset. wikidata.org.
  10. [11] ↑ . Recommended INN: List 5. wikidata.org.
  11. [12] ↑ . Recommended INN: List 5. wikidata.org.
  12. [13] ↑ . sigmaaldrich.com. Retrieved . sigmaaldrich.com. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). tromethamine. Retrieved November 9, 2026, from https://4ort.xyz/entity/tris
MLA “tromethamine.” 4ort.xyz Knowledge Graph, 4ort.xyz, 9 Nov. 2026, https://4ort.xyz/entity/tris.
BibTeX @misc{4ortxyz_tris_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{tromethamine}}, year = {2026}, url = {https://4ort.xyz/entity/tris}, note = {Accessed: 2026-11-09}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): tromethamine — https://4ort.xyz/entity/tris (retrieved 2026-11-09)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 20w ago · Nabbegat · 2026-06-19 view diff on Wikidata ↗
    Instance of → type of chemical entity
    Has use → medication
    Safety classification and labelling → NFPA 704: Standard System for the Identification of the Haza
    Subclass of → chemical compound
    + 3 other properties edited (see Wikidata diff for full list)
    "Changed [tr] labels, descriptions or aliases: QuickStatements 3.0 batch #37300"
Live feed via Wikidata EventStreams. New edits appear within minutes of being made on Wikidata.