TANK binding kinase 1
mammalian protein found in Homo sapiens
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Key Facts
- Physically interacts with: Viroporin 3a[1]
- Part of: Protein kinase-like domain superfamily[2], Protein kinase domain, protein family[3], Protein kinase, ATP binding site, protein family[4]
- Has part(s): protein kinase domain[5], protein kinase, ATP binding site[6]
- EC enzyme number: 2.7.11.1[7]
- Molecular function: transferase activity[8], nucleotide binding[9], kinase activity[10], protein serine/threonine kinase activity[11], phosphoprotein binding[12], protein binding[13], nucleic acid binding[14], ATP binding[15], protein kinase activity[16], identical protein binding[17], protein phosphatase binding[18]
- Cell component: cytoplasm[19], cytosol[20], endosome membrane[21], nucleoplasm[22], aggresome[23]
- Biological process: phosphorylation[24], positive regulation of interferon-alpha production[25], immune system process[26], response to virus[27], positive regulation of xenophagy[28], negative regulation of gene expression[29], positive regulation of peptidyl-serine phosphorylation[30], TRIF-dependent toll-like receptor signaling pathway[31], type I interferon production[32], defense response to virus[33], peptidyl-serine phosphorylation[34], regulation of neuron death[35], activation of innate immune response[36], positive regulation of I-kappaB kinase/NF-kappaB signaling[37]
- Encoded by: TBK1[38]
- Found in taxon: Homo sapiens[39]