semaphorin 4D

mammalian protein found in Homo sapiens
Protein Q21122797

Facts

9 properties
Instance of
protein
Part of
Sema domain superfamily, Immunoglobulin-like fold, semaphorin, Immunoglobulin-like domain superfamily, WD40/YVTN repeat-like-containing domain superfamily, Sema domain, protein family, immunoglobulin subtype, protein family, PSI domain, protein family, Immunoglobulin subtype 2, protein family, immunoglobulin-like domain, protein family, Plexin repeat, protein family, Immunoglobulin domain, protein family[2][3][4][5][6][7][8][9][10][11][12][13]
Biological process
regulation of dendrite morphogenesis, negative regulation of apoptotic process, positive regulation of phosphatidylinositol 3-kinase signaling, multicellular organism development, leukocyte aggregation, nervous system development, negative regulation of cell adhesion, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of axonogenesis, semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis, regulation of cell projection organization, negative regulation of osteoblast differentiation, positive regulation of collateral sprouting, regulation of cell shape, negative regulation of peptidyl-tyrosine phosphorylation, cell differentiation, positive regulation of protein phosphorylation, semaphorin-plexin signaling pathway, cell adhesion, immune response, ossification involved in bone maturation, positive regulation of cell migration, negative regulation of transcription by RNA polymerase II, positive regulation of GTPase activity, negative regulation of alkaline phosphatase activity, negative chemotaxis, neural crest cell migration, positive regulation of cell migration, negative regulation of axon extension involved in axon guidance, semaphorin-plexin signaling pathway, positive regulation of inhibitory synapse assembly, negative regulation of transcription by RNA polymerase II, negative regulation of alkaline phosphatase activity, positive regulation of GTPase activity, ossification involved in bone maturation
Cell component
integral component of membrane, integral component of plasma membrane, membrane, plasma membrane, extracellular space, integral component of plasma membrane
Encoded by
SEMA4D
Found in taxon
Homo sapiens
Has part(s)
immunoglobulin domain, immunoglobulin subtype 2, immunoglobulin-like domain, PSI domain, Plexin repeat, Sema domain, immunoglobulin subtype[14][15][16][17][18][19][20]
Has parts
immunoglobulin domain, immunoglobulin subtype 2, immunoglobulin-like domain, PSI domain, Plexin repeat, Sema domain, immunoglobulin subtype
Molecular function
signaling receptor binding, transmembrane signaling receptor activity, protein binding, semaphorin receptor binding, neuropilin binding, identical protein binding, signaling receptor activity, semaphorin receptor binding, chemorepellent activity
🏷️ Also known as
en A8 en BB18 en CD100 antigen en GR3 en SEMA4D en sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, 4D en sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D en semaphorin 4D en semaphorin-4D ru SEMA4D, CD100 ru Семафорин 4D

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🔗 Connections
Biological process 4
Cell component 2
Part of 2
Found in taxon 1
Has part(s) 1
Instance of 1
Molecular function 1
UniProt protein ID 1
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Summary

semaphorin 4D is a protein[1].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  2. [3] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [4] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [5] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [6] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  6. [7] ↑ . wikidata.org.
  7. [8] ↑ . wikidata.org.
  8. [9] ↑ . wikidata.org.
  9. [10] ↑ . wikidata.org.
  10. [11] ↑ . wikidata.org.
  11. [12] ↑ . wikidata.org.
  12. [13] ↑ . wikidata.org.
  13. [14] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  14. [15] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  15. [16] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  16. [17] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  17. [18] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  18. [19] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  19. [20] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). semaphorin 4D. Retrieved November 12, 2026, from https://4ort.xyz/entity/semaphorin-4d
MLA “semaphorin 4D.” 4ort.xyz Knowledge Graph, 4ort.xyz, 12 Nov. 2026, https://4ort.xyz/entity/semaphorin-4d.
BibTeX @misc{4ortxyz_semaphorin-4d_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{semaphorin 4D}}, year = {2026}, url = {https://4ort.xyz/entity/semaphorin-4d}, note = {Accessed: 2026-11-12}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): semaphorin 4D — https://4ort.xyz/entity/semaphorin-4d (retrieved 2026-11-12)

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