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Pre-mRNA processing factor 3

mammalian protein found in Homo sapiens
Protein Q21118040

Facts

8 properties
Instance of
protein
Part of
U4/U6 small nuclear ribonucleoprotein Prp3, PWI domain superfamily, Domain of unknown function DUF1115, protein family, PWI domain, protein family, Pre-mRNA-splicing factor 3, protein family[2][3][4][5][6]
Biological process
RNA splicing, via transesterification reactions, mRNA splicing, via spliceosome, mRNA processing, spliceosomal tri-snRNP complex assembly, RNA splicing, mRNA splicing, via spliceosome
Cell component
Cajal body, U4/U6 x U5 tri-snRNP complex, spliceosomal complex, nucleus, nucleoplasm, cytosol, nuclear speck, protein-containing complex, U4/U6 x U5 tri-snRNP complex, U2-type precatalytic spliceosome[14][15]
Encoded by
PRPF3
Found in taxon
Homo sapiens
Has part(s)
PWI domain, Domain of unknown function DUF1115, Pre-mRNA-splicing factor 3[7][8][9]
Molecular function
protein binding, identical protein binding, RNA binding, RNA binding[10][11][12][13]
🏷️ Also known as
en hPrp3 en Pre-mRNA processing factor 3 en pre-mRNA-splicing factor 3 en PRP3 pre-mRNA processing factor 3 homolog en PRPF3 en U4/U6-associated RNA splicing factor en U4/U6 small nuclear ribonucleoprotein Prp3 en U4/U6 snRNP 90 kDa protein
🔖 Identifiers · 4
Ensembl protein ID
ENSP00000315379
PDB structure ID
1X4Q, 3JCR
RefSeq protein ID
NP_004689, XP_011508432, XP_011508433, XP_011508434, XP_016858279, XP_016858280, NP_001337458
UniProt protein ID
O43395

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Summary

Pre-mRNA processing factor 3 is a protein[1].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  2. [3] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [4] ↑ . wikidata.org.
  4. [5] ↑ . wikidata.org.
  5. [6] ↑ . wikidata.org.
  6. [7] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  7. [8] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  8. [9] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  9. [10] ↑ . Identification of a PRPF4 loss-of-function variant that abrogates U4/U6.U5 tri-snRNP integration and is associated with retinitis pigmentosa. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [11] ↑ . Dynamic protein-protein interaction wiring of the human spliceosome. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [12] ↑ . The mRNA-Bound Proteome and Its Global Occupancy Profile on Protein-Coding Transcripts. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [13] ↑ . The mRNA-Bound Proteome and Its Global Occupancy Profile on Protein-Coding Transcripts. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] ↑ . RNAi knockdown of hPrp31 leads to an accumulation of U4/U6 di-snRNPs in Cajal bodies. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Pre-mRNA processing factor 3. Retrieved May 3, 2026, from https://4ort.xyz/entity/pre-mrna-processing-factor-3
MLA “Pre-mRNA processing factor 3.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/pre-mrna-processing-factor-3.
BibTeX @misc{4ortxyz_pre-mrna-processing-factor-3_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Pre-mRNA processing factor 3}}, year = {2026}, url = {https://4ort.xyz/entity/pre-mrna-processing-factor-3}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Pre-mRNA processing factor 3 — https://4ort.xyz/entity/pre-mrna-processing-factor-3 (retrieved 2026-05-03)

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