PFN1

protein-coding gene in the species Homo sapiens
Gene gene Q18030490
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Summary

PFN1 is a gene[1]. PFN1 ranks in the top 2% of gene entities by monthly Wikipedia readership (60 views/month).[2]

Key Facts

  • Subclass of: protein-coding gene[3]
  • HomoloGene ID: 3684[4]
  • Genomic start: 4945652[5], 4848947[6]
  • Genomic end: 4949061[7], 4852356[8]
  • Ortholog: Pfn1[9]
  • Encodes: Profilin 1[10]
  • Found in taxon: Homo sapiens[11]
  • Chromosome: human chromosome 17[12]
  • Genetic association: amyotrophic lateral sclerosis type 18[13]
  • Strand orientation: reverse strand[14]
  • Exact match: http://identifiers.org/ncbigene/5216[15]
  • Cytogenetic location: 17p13.2[16]
  • Expressed in: granulocyte[17], mucosa of transverse colon[18], muscle layer of sigmoid colon[19], mucosa of ileum[20], monocyte[21], thoracic aorta[22], ascending aorta[23], stromal cell of endometrium[24], Descending thoracic aorta[25], left coronary artery[26]

Why It Matters

PFN1 is known by 5 alternative names across languages and contexts.[27]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . Ensembl Release 87. wikidata.org.
  2. [4] ↑ . NCBI Gene. Retrieved . wikidata.org.
  3. [5] ↑ . ensembl Release 106. wikidata.org.
  4. [6] ↑ . ensembl Release 106. wikidata.org.
  5. [7] ↑ . ensembl Release 106. wikidata.org.
  6. [8] ↑ . ensembl Release 106. wikidata.org.
  7. [9] ↑ . HomoloGene build68. omabrowser.org. Provenance: wikidata.org.
  8. [10] ↑ . UniProt. Retrieved . wikidata.org.
  9. [11] ↑ . ensembl Release 106. wikidata.org.
  10. [12] ↑ . ensembl Release 106. wikidata.org.
  11. [13] ↑ . UniProt. Retrieved . search.clinicalgenome.org. Provenance: wikidata.org.
  12. [14] ↑ . ensembl Release 106. wikidata.org.
  13. [15] ↑ . Identifiers.org. ebi.ac.uk. Provenance: wikidata.org.
  14. [16] ↑ . NCBI Gene. Retrieved . wikidata.org.
  15. [17] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  16. [18] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  17. [19] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  18. [20] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  19. [21] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  20. [22] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  21. [23] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  22. [24] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  23. [25] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  24. [26] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikimedia Foundation. dumps.wikimedia.org.
  2. [27] ↑ . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). PFN1. Retrieved October 27, 2026, from https://4ort.xyz/entity/pfn1
MLA “PFN1.” 4ort.xyz Knowledge Graph, 4ort.xyz, 27 Oct. 2026, https://4ort.xyz/entity/pfn1.
BibTeX @misc{4ortxyz_pfn1_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{PFN1}}, year = {2026}, url = {https://4ort.xyz/entity/pfn1}, note = {Accessed: 2026-10-27}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): PFN1 — https://4ort.xyz/entity/pfn1 (retrieved 2026-10-27)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 22w ago · Mathieu Kappler · 2026-05-20 view diff on Wikidata ↗
    Hgnc gene symbol → PFN1
    Genetic association → amyotrophic lateral sclerosis type 18
    Refseq rna id → NM_005022, NM_001375991
    Exact match → http://identifiers.org/ncbigene/5216
    + 23 other properties edited (see Wikidata diff for full list)
    "/* wbeditentity-update-languages-short:0||gsw */ QuickStatements 3.0 [[:toollabs:qs-dev/batch/32527|batch #32527]]: human gene name and description in Alemannic"
Live feed via Wikidata EventStreams. New edits appear within minutes of being made on Wikidata.