nitrofurantoin

pharmaceutical drug

Class type of: nitrofuran Q422669

Facts

17 properties

Instance of: type of chemical entity
Subclass of: nitrofuran
Has use: medication
Active ingredient in: Furadantin, Macrodantin
Canonical SMILES: C1C(=O)NC(=O)N1N=CC2=CC=C(O2)[N+](=O)[O-]
Chemical formula: C₈H₆N₄O₅
Defined daily dose: 0.2
Has active ingredient: Nitrofurantoin, Nitrofurantoin Monohydrate
Has part(s): oxygen, carbon
Has parts: oxygen, carbon
Isomeric SMILES: C1C(=O)NC(=O)N1/N=C/C2=CC=C(O2)[N+](=O)[O-]
Mass: 238.033819
Medical condition treated: urinary tract infection, gram-negative bacterial infection, cystitis
NCI Thesaurus ID: C29293
Pregnancy category: Australian pregnancy category A, US pregnancy category B
Subject has role: enzyme inhibitor, urinary anti-infective agents, male reproductive toxicant (1991–present), bactericide, WHO essential medicines
WHO Aware Classification: access

🏷️ Also known as

en 5-Nitrofurantoin en N-(5-Nitrofurfurylidene)-1-aminohydantoin en nitrofurantoin en SID11112186 ar نيتروفورانتوين el Νιτροφουραντοΐνη es nitrofurantoina es nitrofurantoína fa نیتروفورانتوئین fi nitrofurantoiini he ניטרופוראנטואין he ניטרופורנטואין it C8H6N4O5 ja ニトロフラントイン ko macrodantina nl Furabid nl Furadantine nl nitrofurantoïne ro Nitrofurantoină ru Нитрофурантоин

🔖 Identifiers · 37

OpenAlex ID: C2777629877
ATC code: J01XE01
CA PROP 65 ID: nitrofurantoin
CAS Registry Number: 67-20-9
ChEBI ID: 71415
ChEMBL ID: CHEMBL572
ChemSpider ID: 4510228
DSSTOX compound identifier: DTXCID90972
DSSTox substance ID: DTXSID7020972
DrugBank ID: DB00698
DrugCentral ID: 1949
EC number: 200-646-5

Show all 37 identifiers +25

ECHA Substance Infocard ID: 100.000.587
Electronic Essential Medicines List medicine ID: 301
Freebase ID: /m/03554j
Guide to Pharmacology Ligand ID: 10917
InChI: InChI=1S/C8H6N4O5/c13-6-4-11(8(14)10-6)9-3-5-1-2-7(17-5)12(15)16/h1-3H,4H2,(H,10,13,14)/b9-3+
InChIKey: NXFQHRVNIOXGAQ-YCRREMRBSA-N
KEGG ID: D00439
MassBank accession ID: MSBNK-Athens_Univ-AU236157
MeSH descriptor ID: D009582
MeSH tree code: D02.640.600.566, D03.383.312.649.566
MedlinePlus drug identifier: a682291
Microsoft Academic ID (discontinued): 2777629877
NDF-RT ID: N0000147151
NSC number: 757k (2.1k–757k, n=3)
National Drug Code: 72603-176, 82804-241, 48087-0029, 48087-0081, 40032-450, 50090-6664, 62332-389, 71205-852, 71335-1069, 13811-719, 16571-888, 46708-391, 50090-6750, 72789-387, 71052-240, 73212-111, 63629-2464, 70518-4244, 70954-496, 48087-0147, 46708-389, 62332-391, 69238-2512, 60760-853, 62332-390, 65162-689, 67296-1442, 48087-0097, 48087-0146, 60862-006, 43386-450, 64980-593, 68071-3569, 68788-8258, 70377-118, 70518-3717, 71335-1135, 71335-2914, 72789-386, 48087-0009, 31722-491, 50090-7217, 59651-206, 65862-929, 72162-2615, 42571-393, 46708-390, 71335-2320, 72162-1262, 48087-0148
Probes And Drugs ID: PD001838
PubChem CID: 6604200
RxNorm CUI: 7454
SureChEMBL ID: 29470, 26698906
UNII: 927AH8112L
UniChem compound ID: 58701
Wellcome Collection concept ID: qmyzdyy4
WikiProjectMed ID: Nitrofurantoin
WikiSkripta article ID: 61931
WordNet 3.1 Synset ID: 03831983-n

Report an error or request removal Lineage (PROV-JSON)

🔗 Connections

Subject has role 3

bactericide, WHO essential medicines, enzyme inhibitor

Has part(s) 2

oxygen, carbon

Medical condition treated 2

urinary tract infection, cystitis

← Drug or therapy used for treatment 2

urinary tract infection, cystitis

Belongs to 1

World Health Organization Model List of Essential Medicines

Has use 1

medication

Subclass of 1

nitrofuran

Press Enter · cited answer in seconds

Summary

nitrofurantoin is a type of chemical entity^[1].

Key Facts

Canonical SMILES: C1C(=O)NC(=O)N1N=CC2=CC=C(O2)N+[O-]^N+[O-]">[2]
Chemical formula: C₈H₆N₄O₅^[3]
Subclass of: nitrofuran^[4]
Has use: medication^[5]
Has part(s): oxygen^[6], carbon^[7]

nitrofurantoin

Facts

Summary

Key Facts

References

Direct Wikidata claims

Class ancestry

📑 Cite this page