melittin

pore-forming toxin in honey bees

ChemicalSubstance peptide Q424512

Facts

8 properties

Instance of: peptide, protein fragment^[2]
Part of: apitoxin, Melittin family^[5]^[6]
Active ingredient in: apitoxin
Canonical SMILES: CCC(C)C(C(=O)NCC(=O)NC(C)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NC(C(C)O)C(=O)NC(C(C)O)C(=O)NCC(=O)NC(CC(C)C)C(=O)N1CCCC1C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)NC(C(C)CC)C(=O)NC(CO)C(=O)NC(CC2=CNC3=CC=CC=C32)C(=O)NC(C(C)CC)C(=O)NC(CCCCN)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)N)NC(=O)CN^[3]
Chemical formula: C₁₃₁H₂₂₉N₃₉O₃₁^[4]
Found in taxon: Apis mellifera
Isomeric SMILES: CC[C@H](C)[C@H](NC(=O)CN)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(N)=O)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)[C@@H](C)O)C(C)C)C(C)C
Mass: 2845.757527

🏷️ Also known as

en melitten en Melittin en melittin en bee venom melittin en Forapin en Forapine en GIGAVLKVLTTGLPALISWIKRKRQQ-NH2 en Honeybee melittin ar مليتين cs melitin de Mellitin es Melitina fa ملیتین fr Mélittine he מליטין it Melittina ja メリチン nl Mellitine pl Melityna ru Мелитин

🔖 Identifiers · 26

OpenAlex ID: C2778001312
CAS Registry Number: 20449-79-0
ChEBI ID: 6736
ChEMBL ID: CHEMBL412927
ChemSpider ID: 17290230
CosIng number: 92044
DSSTox substance ID: DTXSID001046261
EC number: 629-303-1
ECHA Substance Infocard ID: 100.157.496
Freebase ID: /m/0491r9
InChI: InChI=1S/C131H229N39O31/c1-23-71(16)102(163-97(176)60-135)122(194)146-62-98(177)148-74(19)109(181)164-100(69(12)13)124(196)160-88(55-65(4)5)116(188)155-84(41-30-33-51-134)115(187)165-101(70(14)15)125(197)161-90(57-67(8)9)118(190)168-106(77(22)173)128(200)169-105(76(21)172)123(195)147-63-99(178)150-92(58-68(10)11)129(201)170-54-36-44-94(170)121(193)149-75(20)108(180)158-89(56-66(6)7)117(189)166-104(73(18)25-3)127(199)162-93(64-171)120(192)159-91(59-78-61-145-80-38-27-26-37-79(78)80)119(191)167-103(72(17)24-2)126(198)157-83(40-29-32-50-133)111(183)154-85(42-34-52-143-130(139)140)112(184)152-82(39-28-31-49-132)110(182)153-86(43-35-53-144-131(141)142)113(185)156-87(46-48-96(137)175)114(186)151-81(107(138)179)45-47-95(136)174/h26-27,37-38,61,65-77,81-94,100-106,145,171-173H,23-25,28-36,39-60,62-64,132-135H2,1-22H3,(H2,136,174)(H2,137,175)(H2,138,179)(H,146,194)(H,147,195)(H,148,177)(H,149,193)(H,150,178)(H,151,186)(H,152,184)(H,153,182)(H,154,183)(H,155,188)(H,156,185)(H,157,198)(H,158,180)(H,159,192)(H,160,196)(H,161,197)(H,162,199)(H,163,176)(H,164,181)(H,165,187)(H,166,189)(H,167,191)(H,168,190)(H,169,200)(H4,139,140,143)(H4,141,142,144)/t71-,72-,73-,74-,75-,76+,77+,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,100-,101-,102-,103-,104-,105-,106-/m0/s1
InChIKey: VDXZNPDIRNWWCW-JFTDCZMZSA-N

Show all 26 identifiers +14

KEGG ID: C11198
MeSH descriptor ID: D008555
MeSH tree code: D12.644.050.550, D12.644.066.500.550, D12.776.543.695.054.550, D20.888.065.115.580, D23.946.833.065.115.580
Microsoft Academic ID (discontinued): 2778001312
Probes And Drugs ID: PD017475
PubChem CID: 16133648, 60207992
Reaxys registry number: 14626573
SureChEMBL ID: 29351537
Transporter Classification Database ID: 1.C.18.1.1
UMLS CUI: C0025234
UNII: 24VT8NVE75
UniChem compound ID: 139910
UniProt protein ID: P01501
WikiSkripta article ID: 18774

🔗 Connections

Active ingredient in 1

apitoxin

Found in taxon 1

Apis mellifera

Instance of 1

peptide

Part of 1

apitoxin

← Has active ingredient 1

apitoxin

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Summary

melittin is a peptide^[1].

melittin

Facts

Summary

References

Direct Wikidata claims

Class ancestry

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