major depressive disorder

mood disorder characterized by persistent low mood, motivation, and self-esteem, accompanied by loss of interest or pleasure and impairment of functioning
MedicalCondition class_of_disease Q42844
major depressive disorder
Vincent van Gogh · Public Domain · Wikimedia
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major depressive disorder

Summary

major depressive disorder is a class of disease[1]. It ranks in the top 1% of class_of_disease entities by monthly Wikipedia readership (69,464 views/month).[2]

Key Facts

  • major depressive disorder's instance of is recorded as class of disease[3].
  • major depressive disorder is a type of depressive disorder[4].
  • major depressive disorder is a type of depression[5].
  • major depressive disorder is a type of mental health[6].
  • major depressive disorder's Commons category is recorded as Major depressive disorder[7].
  • major depressive disorder's said to be the same as is recorded as depressive personality disorder[8].
  • major depressive disorder's symptoms and signs is recorded as dysphoria[9].
  • major depressive disorder's symptoms and signs is recorded as fatigue[10].
  • major depressive disorder's symptoms and signs is recorded as executive disfunction[11].
  • major depressive disorder's symptoms and signs is recorded as depression[12].
  • major depressive disorder's symptoms and signs is recorded as eating disorder[13].
  • major depressive disorder's symptoms and signs is recorded as sleep disorder[14].
  • major depressive disorder's symptoms and signs is recorded as depressive syndrome[15].
  • major depressive disorder's has cause is recorded as genetics[16].
  • major depressive disorder's has cause is recorded as environmental factor[17].
  • major depressive disorder's has cause is recorded as meaning of life[18].
  • major depressive disorder's possible treatment is recorded as antidepressant[19].
  • major depressive disorder's possible treatment is recorded as electroconvulsive therapy[20].
  • major depressive disorder's possible treatment is recorded as psychotherapy[21].
  • major depressive disorder's possible treatment is recorded as transcranial magnetic stimulation[22].
  • major depressive disorder's possible treatment is recorded as light therapy[23].
  • major depressive disorder's facet of is recorded as women's health[24].
  • major depressive disorder's facet of is recorded as men's health[25].
  • major depressive disorder's described by source is recorded as Otto's encyclopedia[26].
  • major depressive disorder's described by source is recorded as Merck Manual of Diagnosis and Therapy[27].

Body

Works and Contributions

Things named for major depressive disorder include Depression Quest[28], a video game[29].

Why It Matters

major depressive disorder ranks in the top 1% of class_of_disease entities by monthly Wikipedia readership (69,464 views/month).[2] It has Wikipedia articles in 30 language editions, a strong signal of global cultural recognition.[30] It is known by 166 alternative names across languages and contexts.[31]

Entities named for it include Depression Quest[28], a video game[29].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . wikidata.org.
  2. [4] ↑ . wikidata.org.
  3. [5] ↑ . Disease Ontology. Retrieved . wikidata.org.
  4. [6] ↑ . wikidata.org.
  5. [7] ↑ . wikidata.org.
  6. [8] ↑ . wikidata.org.
  7. [9] ↑ . wikidata.org.
  8. [10] ↑ . wikidata.org.
  9. [11] ↑ . wikidata.org.
  10. [12] ↑ . Altered cortical glutamatergic and GABAergic signal transmission with glial involvement in depression. wikidata.org.
  11. [13] ↑ . wikidata.org.
  12. [14] ↑ . wikidata.org.
  13. [15] ↑ . wikidata.org.
  14. [16] ↑ . wikidata.org.
  15. [17] ↑ . wikidata.org.
  16. [18] ↑ . wikidata.org.
  17. [19] ↑ . wikidata.org.
  18. [20] ↑ . wikidata.org.
  19. [21] ↑ . wikidata.org.
  20. [22] ↑ . wikidata.org.
  21. [23] ↑ . wikidata.org.
  22. [24] ↑ . wikidata.org.
  23. [25] ↑ . wikidata.org.
  24. [26] ↑ . wikidata.org.
  25. [27] ↑ . msdmanuals.com.. msdmanuals.com.. Provenance: wikidata.org.

Inverse relationships (entities pointing at this one)

  1. [28] ↑ . wikidata.org. → on this site

Inline context (facts about related entities)

  1. [29] ↑ . Wikidata. wikidata.org. → on this site

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikimedia Foundation. dumps.wikimedia.org.
  2. [30] ↑ . Wikidata sitelinks. wikidata.org.
  3. [31] ↑ . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). major depressive disorder. Retrieved October 3, 2026, from https://4ort.xyz/entity/major-depressive-disorder
MLA “major depressive disorder.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 Oct. 2026, https://4ort.xyz/entity/major-depressive-disorder.
BibTeX @misc{4ortxyz_major-depressive-disorder_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{major depressive disorder}}, year = {2026}, url = {https://4ort.xyz/entity/major-depressive-disorder}, note = {Accessed: 2026-10-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): major depressive disorder — https://4ort.xyz/entity/major-depressive-disorder (retrieved 2026-10-03)

Canonical URL: https://4ort.xyz/entity/major-depressive-disorder · Last refreshed:

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 6d ago · MatSuBot bot · 2026-09-29 view diff on Wikidata ↗
    Sitelink count → 100
    Wikipedia languages → ['af', 'ar', 'as', 'ast', 'az', 'azb', 'be', 'be_x_old', 'bg', 'bn', 'bs', 'ca',
    Claims rich → —
    "/* wbeditentity-update-languages-short:0||te, ja */ import labels from sitelinks; cleanup"
  2. 15d ago · Sarthorial · 2026-09-20 view diff on Wikidata ↗
    Encyclopædia britannica online id → science/major-depressive-disorder
    Wordnet 3.1 synset id → 14412645-n
    Has cause → genetics, environmental factor, meaning of life
    "/* wbsetclaim-update:2||1 */ [[Property:P828]]: [[Q223675]]"
  3. 12w ago · Nyuhn · 2026-07-10 view diff on Wikidata ↗
    P14541 → q4Cvj
    "/* wbeditentity-update:0| */ QuickStatements 3.0 [[:toollabs:qs-dev/batch/40849|batch #40849]]: ZGBK ID"
  4. 13w ago · JhealdBatch bot · 2026-07-03 view diff on Wikidata ↗
    Subclass of → depressive disorder, depression, mental health
    "/* wbeditentity-update:0| */ QuickStatements 3.0 [[:toollabs:qs-dev/batch/39732|batch #39732]]: rm redundant subclass"
  5. 16w ago · Jindřich Rubeš · 2026-06-14 view diff on Wikidata ↗
    Svkkl authority id → h0002711-deprese
    "/* wbcreateclaim-create:1| */ [[Property:P9322]]: h0002711-deprese, [[:toollabs:quickstatements/#/batch/259662|batch #259662]]"
  6. 19w ago · Yxnoux · 2026-05-19 view diff on Wikidata ↗
    Possible treatment → antidepressant, electroconvulsive therapy, psychotherapy +2
    Maintained by wikiproject → WikiProject Psychology, WikiProject Neuroscience, WikiProject Medicine +9
    Aliases → —
    Subclass of → —
    + 17 other properties edited (see Wikidata diff for full list)
    "/* wbsetclaim-create:2||1 */ [[Property:P2176]]: [[Q3563148]]"
Live feed via Wikidata EventStreams. New edits appear within minutes of being made on Wikidata.