intercellular adhesion molecule 1
mammalian protein found in Homo sapiens
Facts
10 properties- Instance of
- protein
- Subclass of
- cell adhesion molecule[2]
- Part of
- Immunoglobulin-like fold, Immunoglobulin-like domain superfamily, immunoglobulin subtype, protein family, Intercellular adhesion molecule, N-terminal domain, protein family, Intercellular adhesion molecule, Intercellular adhesion molecule/vascular cell adhesion molecule, N-terminal domain, protein family[3][4][5][6][7][8]
- Biological process
- leukocyte cell-cell adhesion, response to ionizing radiation, establishment of endothelial barrier, negative regulation of endothelial cell apoptotic process, cellular response to organic substance, heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules, response to amino acid, response to hypoxia, positive regulation of actin filament polymerization, response to organic cyclic compound, T cell antigen processing and presentation, establishment of Sertoli cell barrier, response to sulfur dioxide, response to copper ion, interferon-gamma-mediated signaling pathway, positive regulation of nitric oxide biosynthetic process, response to amphetamine, cellular response to tumor necrosis factor, regulation of leukocyte mediated cytotoxicity, T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell, extracellular matrix organization, acute inflammatory response to antigenic stimulus, hearing, cellular response to alkaloid, response to gonadotropin, positive regulation of cellular extravasation, positive regulation of GTPase activity, response to lipopolysaccharide, regulation of cell adhesion, cell adhesion, cell adhesion mediated by integrin, positive regulation of NF-kappaB transcription factor activity, negative regulation of extrinsic apoptotic signaling pathway via death domain receptors, positive regulation of vasoconstriction, cellular response to interleukin-1, cellular response to nutrient levels, negative regulation of calcium ion transport, regulation of cell shape, membrane to membrane docking, positive regulation of peptidyl-tyrosine phosphorylation, ovarian follicle development, regulation of immune response, positive regulation of ERK1 and ERK2 cascade, regulation of ruffle assembly, viral entry into host cell, response to ethanol, viral process, cellular response to lipopolysaccharide, cellular response to hypoxia, leukocyte migration, cellular response to glucose stimulus, response to insulin, cellular response to interferon-gamma, cellular response to interleukin-6, cellular response to dexamethasone stimulus, establishment of endothelial intestinal barrier, positive regulation of leukocyte adhesion to vascular endothelial cell, cellular response to leukemia inhibitory factor, cell-cell adhesion, cell adhesion, cytokine-mediated signaling pathway, T cell extravasation, cellular response to amyloid-beta
- Cell component
- integral component of membrane, membrane, focal adhesion, plasma membrane, integral component of plasma membrane, cell surface, immunological synapse, membrane raft, extracellular exosome, external side of plasma membrane, extracellular space, extracellular matrix, integral component of plasma membrane, focal adhesion, cell surface, membrane, collagen-containing extracellular matrix, extracellular exosome
- Encoded by
- ICAM1
- Found in taxon
- Homo sapiens
- Has part(s)
- Intercellular adhesion molecule/vascular cell adhesion molecule, N-terminal, Intercellular adhesion molecule, N-terminal, Intercellular adhesion molecule domain, immunoglobulin subtype[9][10][11][12]
- Has parts
- Intercellular adhesion molecule/vascular cell adhesion molecule, N-terminal, Intercellular adhesion molecule, N-terminal, Intercellular adhesion molecule domain, immunoglobulin subtype
- Molecular function
- virus receptor activity, protein-containing complex binding, integrin binding, protein binding, transmembrane signaling receptor activity, integrin binding, signaling receptor activity
🏷️ Also known as
en intercellular adhesion molecule 1 (CD54), human rhinovirus receptor
en major group rhinovirus receptor
en cell surface glycoprotein P3.58
en epididymis secretory sperm binding protein
en ICAM-1
en ICAM1
en intercellular adhesion molecule 1
en Intercellular adhesion molecule 1
ar جزيء لاصق بين الخلايا-1
de Interzelluläres Zelladhäsionsmolekül 1
ru CD54
ru ICAM1
🔖 Identifiers · 11
- OpenAlex ID
- C185946421
- Image (Wikimedia Commons)
- ICAM1.png ↗
- Ensembl protein ID
- ENSP00000264832, ENSP00000413124, ENSP00000465680
- Freebase ID
- /m/058vl7
- MeSH descriptor ID
- D018799
- MeSH tree code
- D12.776.395.550.200.450, D12.776.543.550.200.450, D23.050.301.350.450, D09.400.430.890.200.450
- Microsoft Academic ID (discontinued)
- 185946421
- RefSeq protein ID
- NP_000192
- UMLS CUI
- C0063695
- UniProt protein ID
- P05362
🔗 Connections
Cell component 9
Biological process 4
Found in taxon 1
Instance of 1
Molecular function 1
Part of 1
Subclass of 1
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Summary
intercellular adhesion molecule 1 is a protein[1].