Gasdermin D
mammalian protein found in Homo sapiens
Facts
8 properties- Instance of
- protein
- Part of
- gasdermin[2]
- Biological process
- cellular response to extracellular stimulus, innate immune response, inflammatory response, programmed cell death, immune system process, pyroptosis, cytolysis, pore formation in membrane of other organism, neutrophil degranulation, pore complex assembly, defense response to Gram-negative bacterium, defense response to Gram-positive bacterium, protein homooligomerization, pyroptosis
- Cell component
- cytoplasm, inflammasome complex, nucleoplasm, NLRP3 inflammasome complex, extracellular region, extracellular space, cytosol, plasma membrane, membrane, specific granule lumen, tertiary granule lumen, ficolin-1-rich granule lumen, NLRP3 inflammasome complex[12][13][14][15][16][17][18][19][20][21]
- Encoded by
- GSDMD
- Found in taxon
- Homo sapiens
- Imported from
- wholeness_audit_2026-05-02
- Molecular function
- protein binding, phosphatidylserine binding, phosphatidylinositol-4,5-bisphosphate binding, phosphatidylinositol-4-phosphate binding, phosphatidic acid binding, cardiolipin binding, phosphatidylserine binding, phosphatidylinositol-4,5-bisphosphate binding, phosphatidylinositol-4-phosphate binding[3][4][5][6][7][8][9][10][11]
🏷️ Also known as
en gasdermin-D
en Gasdermin D
en gasdermin domain containing 1
en gasdermin domain-containing protein 1
en GSDMD
🔖 Identifiers · 5
- Ensembl protein ID
- ENSP00000262580, ENSP00000433209, ENSP00000482096, ENSP00000488012, ENSP00000487934, ENSP00000434452, ENSP00000486410, ENSP00000488049, ENSP00000487774, ENSP00000432351, ENSP00000434386, ENSP00000488563, ENSP00000437065, ENSP00000433958, ENSP00000436684, ENSP00000488419, ENSP00000488317, ENSP00000433263
- Exact match
- identifiers.org, purl.uniprot.org, www.ncbi.nlm.nih.gov
- RefSeq protein ID
- NP_001159709, NP_079012, XP_011515603
- Transporter Classification Database ID
- 1.C.123.1.1
- UniProt protein ID
- P57764
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Summary
Gasdermin D is a protein[1].