Home › Entities › (RS)-ketamine › esketamine

esketamine

chemical compound
Class type of: (RS)-ketamine Q2365493

Facts

14 properties
Instance of
type of chemical entity
Subclass of
(RS)-ketamine
Has use
medication[11]
Active ingredient in
Spravato[18]
Canonical SMILES
CNC1(CCCCC1=O)C2=CC=CC=C2Cl[9]
Chemical formula
C₁₃H₁₆ClNO[10]
Different from
(RS)-ketamine[12]
Isomeric SMILES
CN[C@@]1(CCCCC1=O)C2=CC=CC=C2Cl[13]
Mass
+237.092042[14]
Medical condition treated
treatment-resistant depression[15]
Physically interacts with
Glutamate ionotropic receptor NMDA type subunit 2D, Glutamate ionotropic receptor NMDA type subunit 3A, Glutamate ionotropic receptor NMDA type subunit 2C, Glutamate ionotropic receptor NMDA type subunit 2A, Glutamate ionotropic receptor NMDA type subunit 1, Glutamate ionotropic receptor NMDA type subunit 2B[3][4][5][6][7][8]
Stereoisomer of
arketamine[17]
Substance control status
Schedule III (United States)[19]
World Health Organisation international non-proprietary name
esketamine[16]
🏷️ Also known as
en (S)-2-(o-chlorophenyl)-2-(methylamino)cyclohexanone en (S)-ketamine en (S)-(-)-ketamine en esketamine en (-)-ketamine ar إيسكيتامين de (S)-Ketamin de Esketamin es esketamina fa اسکتامین fi esketamiini fr eskétamine he אסקטמין ja エスケタミン ko 스프라바토 pl esketamina pl (S)-ketamina pt escetamina ro esketamină ru эскетамин
🔖 Identifiers · 29
ATC code
N01AX14
CAS Registry Number
33643-46-8
ChEBI ID
60799
ChEMBL ID
CHEMBL395091
ChemSpider ID
158414
DSSTOX compound identifier
DTXCID4027787
DSSTox substance ID
DTXSID6047810
DrugBank ID
DB11823
DrugCentral ID
4468
EC number
811-504-2
ECHA Substance Infocard ID
100.242.065
Freebase ID
/m/02x51zd
Show all 29 identifiers +17
Guide to Pharmacology Ligand ID
9152
InChI
InChI=1S/C13H16ClNO/c1-15-13(9-5-4-8-12(13)16)10-6-2-3-7-11(10)14/h2-3,6-7,15H,4-5,8-9H2,1H3/t13-/m0/s1
InChIKey
YQEZLKZALYSWHR-ZDUSSCGKSA-N
KEGG ID
D07283
MedlinePlus drug identifier
a619017
Microsoft Academic ID (discontinued)
2779656843
PDB ligand ID
JC9
Probes And Drugs ID
PD050157
PubChem CID
182137
Reaxys registry number
4295313
RxNorm CUI
2119365
SureChEMBL ID
5512024
UK Parliament thesaurus ID
525773
UNII
50LFG02TXD
UniChem compound ID
7853
WikiProjectMed ID
Esketamine
YSO ID
27445

Report an error or request removal Lineage (PROV-JSON)

🔗 Connections
Different from 1
(RS)-ketamine
Has use 1
medication
Medical condition treated 1
treatment-resistant depression
Stereoisomer of 1
arketamine
Subclass of 1
(RS)-ketamine
← Different from 1
(RS)-ketamine
← Stereoisomer of 1
arketamine
Press Enter · cited answer in seconds

Summary

esketamine is a type of chemical entity[1]. esketamine is a type of (RS)-ketamine[2].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . Open Targets Platform. Retrieved . platform.opentargets.org. Provenance: wikidata.org.
  2. [4] ↑ . Open Targets Platform. Retrieved . platform.opentargets.org. Provenance: wikidata.org.
  3. [5] ↑ . Open Targets Platform. Retrieved . platform.opentargets.org. Provenance: wikidata.org.
  4. [6] ↑ . Open Targets Platform. Retrieved . platform.opentargets.org. Provenance: wikidata.org.
  5. [7] ↑ . Open Targets Platform. Retrieved . platform.opentargets.org. Provenance: wikidata.org.
  6. [8] ↑ . Open Targets Platform. Retrieved . platform.opentargets.org. Provenance: wikidata.org.
  7. [9] ↑ . PubChem. Retrieved . wikidata.org.
  8. [10] ↑ . PubChem. Retrieved . wikidata.org.
  9. [2] ↑ . wikidata.org.
  10. [11] ↑ . wikidata.org.
  11. [12] ↑ . wikidata.org.
  12. [13] ↑ . PubChem. Retrieved . wikidata.org.
  13. [14] ↑ . PubChem. Retrieved . wikidata.org.
  14. [15] ↑ . wikidata.org.
  15. [16] ↑ . ChEBI. Retrieved . wikidata.org.
  16. [17] ↑ . wikidata.org.
  17. [18] ↑ . wikidata.org.
  18. [19] ↑ . Retrieved . wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). esketamine. Retrieved November 14, 2026, from https://4ort.xyz/entity/esketamine
MLA “esketamine.” 4ort.xyz Knowledge Graph, 4ort.xyz, 14 Nov. 2026, https://4ort.xyz/entity/esketamine.
BibTeX @misc{4ortxyz_esketamine_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{esketamine}}, year = {2026}, url = {https://4ort.xyz/entity/esketamine}, note = {Accessed: 2026-11-14}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): esketamine — https://4ort.xyz/entity/esketamine (retrieved 2026-11-14)

Canonical URL: https://4ort.xyz/entity/esketamine · Last refreshed:

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 10d ago · Elivan da Silva · 2026-11-04 view diff on Wikidata ↗
    "Added reference: ATC code: N01AX14, #temporary_batch_1793797308716"
  2. 6w ago · MsynBot bot · 2026-10-02 view diff on Wikidata ↗
    "Changed the item: remove badge intentional sitelink to redirect from dewiki sitelink; sitelink points to a non-redirect page #msynbotTask10"
  3. 10w ago · Carn · 2026-08-31 view diff on Wikidata ↗
    Substance control status → Schedule III (United States)
    "Created claim: Substance control status: Schedule III (United States), batch #269907"
  4. 20w ago · FlocciNivis · 2026-06-25 view diff on Wikidata ↗
    PDB ligand ID → JC9
    "Created claim: PDB ligand ID: JC9, batch #259826"
  5. 25w ago · Twofivesixbot bot · 2026-05-19 view diff on Wikidata ↗
    Instance of → type of chemical entity
    Medical condition treated → treatment-resistant depression
    Active ingredient in → Spravato
    Different from → (RS)-ketamine
    + 5 other properties edited (see Wikidata diff for full list)
    "Changed claim qualifiers: YSO ID: 27445, mv to monolingual text names on YSO statements"
Live feed via Wikidata EventStreams. New edits appear within minutes of being made on Wikidata.