empagliflozin

Diabetes Drug

Class type of: chemical compound Q5373824

Facts

13 properties

Instance of: type of chemical entity
Subclass of: chemical compound
Has use: medication
Active ingredient in: Jardiance
Canonical SMILES: C1COCC1OC2=CC=C(C=C2)CC3=C(C=CC(=C3)C4C(C(C(C(O4)CO)O)O)O)Cl
Chemical formula: C₂₃H₂₇ClO₇
Defined daily dose: +17.5
Isomeric SMILES: C1COC[C@H]1OC2=CC=C(C=C2)CC3=C(C=CC(=C3)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)Cl
Mass: +450.144531
Medical condition treated: type-1 diabetes
Physically interacts with: Solute carrier family 5 member 1, Solute carrier family 5 member 2
Pregnancy category: US pregnancy category C
Subject has role: anti-diabetic medication, gliflozins

🏷️ Also known as

en empagliflozin en Empagliflozin en 1-chloro-4-(glucopyranos-1-yl)-2-(4-(tetrahydrofuran-3-yloxy)benzyl)benzene en (1S)-1,5-anhydro-1-(4-chloro-3-{4-[(3S)-tetrahydrofuran-3-yloxy]benzyl}phenyl)-D-glucitol en (1S)-1,5-anhydro-1-C-{4-chloro-3-((4-{((3S)-oxolan-3-yl)oxy}phenyl)methyl)phenyl}-D-glucitol en BI 10773 en BI-10773 en BI10773 ar أمباغليفلوزين el Εμπαγλιφλοζίνη es Empagliflozina fa امپاگلیفلوزین fi empagliflotsiini fr empagliflozine he אמפאגליפלוזין ja エンパグリフロジン ko 엠파글리플로진 pl empagliflozyna ro Empagliflozină ru Jardiance

🔖 Identifiers · 32

OpenAlex ID: C2775887513
ATC code: A10BX12, A10BK03
CAB ID: 144342
CAS Registry Number: 864070-44-0
ChEBI ID: 82720
ChEMBL ID: CHEMBL2107830
ChemSpider ID: 10123957
DSSTox substance ID: DTXSID601026093
DrugBank ID: DB09038
DrugCentral ID: 4830
EC number: 620-176-8
ECHA Substance Infocard ID: 100.122.058

Show all 32 identifiers +20

Freebase ID: /m/0n49z1d
Guide to Pharmacology Ligand ID: 4754
InChI: InChI=1S/C23H27ClO7/c24-18-6-3-14(23-22(28)21(27)20(26)19(11-25)31-23)10-15(18)9-13-1-4-16(5-2-13)30-17-7-8-29-12-17/h1-6,10,17,19-23,25-28H,7-9,11-12H2/t17-,19+,20+,21-,22+,23-/m0/s1
InChIKey: OBWASQILIWPZMG-QZMOQZSNSA-N
KEGG ID: D10459
MeSH descriptor ID: C570240
MedlinePlus drug identifier: a614043
Microsoft Academic ID (discontinued): 2775887513
NDF-RT ID: N0000190927
PDB ligand ID: 7R3
Probes And Drugs ID: PD009397
PubChem CID: 11949646
Reaxys registry number: 12378768
RxNorm CUI: 1545653
Römpp online ID: RD-05-03302
SureChEMBL ID: 899986
UMLS CUI: C3490348, C3490349
UNII: HDC1R2M35U
UniChem compound ID: 27288619
WikiProjectMed ID: Empagliflozin

Report an error or request removal Lineage (PROV-JSON)

🔗 Connections

Subject has role 2

anti-diabetic medication, gliflozins

Belongs to 1

World Health Organization Model List of Essential Medicines

Has use 1

medication

Medical condition treated 1

type-1 diabetes

Physically interacts with 1

Solute carrier family 5 member 1

Subclass of 1

chemical compound

← Physically interacts with 1

Solute carrier family 5 member 1

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Summary

empagliflozin is a type of chemical entity^[1]. empagliflozin is a type of chemical compound^[2].

Key Facts

Physically interacts with: Solute carrier family 5 member 1^[3], Solute carrier family 5 member 2^[4]
Canonical SMILES: C1COCC1OC2=CC=C(C=C2)CC3=C(C=CC(=C3)C4C(C(C(C(O4)CO)O)O)O)Cl^[5]
Chemical formula: C₂₃H₂₇ClO₇^[6]
Has use: medication^[7]
Isomeric SMILES: C1COC[C@H]1OC2=CC=C(C=C2)CC3=C(C=CC(=C3)[C@H]4C@@HO)Cl^{C@@HO)Cl">[8]}
Mass: 450.144531 dalton^[9]
Medical condition treated: type-1 diabetes^[10]
Subject has role: anti-diabetic medication^[11], gliflozins^[12]
Pregnancy category: US pregnancy category C^[13]
Active ingredient in: Jardiance^[14]
Defined daily dose: 17.5 milligram^[15]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[3] ↑ empagliflozin — physically interacts with (P129): Solute carrier family 5 member 1. IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved 2016-08-17. wikidata.org.
[4] ↑ empagliflozin — physically interacts with (P129): Solute carrier family 5 member 2. IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved 2016-08-17. wikidata.org.
[5] ↑ empagliflozin — canonical SMILES (P233): C1COCC1OC2=CC=C(C=C2)CC3=C(C=CC(=C3)C4C(C(C(C(O4)CO)O)O)O)Cl. PubChem. Retrieved 2016-11-20. wikidata.org.
[6] ↑ empagliflozin — chemical formula (P274): C₂₃H₂₇ClO₇. PubChem. Retrieved 2016-11-20. wikidata.org.
[2] ↑ empagliflozin — subclass of (P279): chemical compound. wikidata.org.
[7] ↑ empagliflozin — has use (P366): medication. wikidata.org.
[8] ↑ empagliflozin — isomeric SMILES (P2017): C1COC[C@H]1OC2=CC=C(C=C2)CC3=C(C=CC(=C3)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)Cl. PubChem. Retrieved 2016-11-20. wikidata.org.
[9] ↑ empagliflozin — mass (P2067): 450.144531 dalton. PubChem. Retrieved 2016-10-03. wikidata.org.
[10] ↑ empagliflozin — medical condition treated (P2175): type-1 diabetes. Drug Indications Extracted from FAERS. Retrieved 2018-10-02. wikidata.org.
[11] ↑ empagliflozin — subject has role (P2868): anti-diabetic medication. Medical Subject Headings. Retrieved 2018-03-15. wikidata.org.
[12] ↑ empagliflozin — subject has role (P2868): gliflozins. wikidata.org.
[13] ↑ empagliflozin — pregnancy category (P3489): US pregnancy category C. wikidata.org.
[14] ↑ empagliflozin — active ingredient in (P3780): Jardiance. RxNorm. Retrieved 2018-02-14. wikidata.org.
[15] ↑ empagliflozin — defined daily dose (P4250): 17.5 milligram. whocc.no. whocc.no. Provenance: wikidata.org.

Class ancestry

[1] ↑ empagliflozin is an instance of type of chemical entity (Q113145171) [P31, primary]. Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). empagliflozin. Retrieved November 10, 2026, from https://4ort.xyz/entity/empagliflozin

MLA “empagliflozin.” 4ort.xyz Knowledge Graph, 4ort.xyz, 10 Nov. 2026, https://4ort.xyz/entity/empagliflozin.

BibTeX

@misc{4ortxyz_empagliflozin_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{empagliflozin}}, year = {2026}, url = {https://4ort.xyz/entity/empagliflozin}, note = {Accessed: 2026-11-10}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): empagliflozin — https://4ort.xyz/entity/empagliflozin (retrieved 2026-11-10)

Canonical URL: https://4ort.xyz/entity/empagliflozin · Last refreshed: November 10, 2026

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

7d ago · Elivan da Silva · 2026-11-04 view diff on Wikidata ↗

"Added reference: ATC code: A10BK03, #temporary_batch_1793797647845"
19w ago · FlocciNivis · 2026-06-25 view diff on Wikidata ↗

Pregnancy category → US pregnancy category C

Subclass of → chemical compound

Mass → 450.144531 dalton

Has use → medication

+ 7 other properties edited (see Wikidata diff for full list)

"Created claim: PDB ligand ID: 7R3, batch #259826"

Live feed via Wikidata EventStreams. New edits appear within minutes of being made on Wikidata.