dexmedetomidine
chemical compound
Facts
16 properties- Instance of
- type of chemical entity
- Subclass of
- medetomidine
- Has use
- medication
- Active ingredient in
- Precedex
- Canonical SMILES
- CC1=C(C(=CC=C1)C(C)C2=CN=CN2)C
- Chemical formula
- C₁₃H₁₆N₂
- Defined daily dose
- +1
- Isomeric SMILES
- CC1=C(C(=CC=C1)[C@H](C)C2=CN=CN2)C
- Mass
- +200.131349
- Medical condition treated
- pain, agitation in dementia
- Physically interacts with
- Adrenoceptor alpha 2A, Adrenoceptor alpha 2B, Adrenoceptor alpha 2C
- Pregnancy category
- US pregnancy category C
- Significant drug interaction
- pethidine, pethidine, periciazine, tramadol, tramadol, (RS)-methadone, (RS)-methadone, morphine, morphine, oxycodone, oxycodone, hydromorphone, hydromorphone, dihydrocodeine, dihydrocodeine, codeine, codeine, tapentadol, tapentadol, buprenorphine, fentanyl, alfentanil, alfentanil, alfentanil, sufentanil, sufentanil, loxapine, loxapine, loxapine, loxapine, loxapine, sodium oxybate
- Stereoisomer of
- levomedetomidine
- Subject has role
- non-opioid analgesic, Adrenergic alpha-2 Receptor Agonists, hypnotics and sedatives
- World Health Organisation international non-proprietary name
- dexmedetomidine
🏷️ Also known as
en (S)-medetomidine
en (+)-4-((S)-alpha,2,3-trimethylbenzyl)imidazole
en (+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazole
en Dexmedetomidin
en Dexmedetomidina
en dexmedetomidine
en Dexmedetomidine
en Dexmédétomidine
en Dexmedetomidinum
en (+)-medetomidine
en MPV 1440
en Precedex®
ar ديكسميديتوميدين
fa دکسمدتومیدین
fi deksmedetomidiini
fr 113775-47-6
id Deksmedetomidin
ja デクスメデトミジン
pl Deksmedetomidyna
ro Dexmedetomidină
🔖 Identifiers · 34
- OpenAlex ID
- C2781302539
- ATC code
- N05CM18
- CAS Registry Number
- 113775-47-6
- ChEBI ID
- 4466
- ChEMBL ID
- CHEMBL778
- ChemSpider ID
- 4470605
- DSSTOX compound identifier
- DTXCID00820907
- DSSTox substance ID
- DTXSID10873388
- DrugBank ID
- DB00633
- DrugCentral ID
- 835
- EC number
- 601-281-8
- ECHA Substance Infocard ID
- 100.119.391
Show all 34 identifiers +22
- Freebase ID
- /m/0g8_7x
- Guide to Pharmacology Ligand ID
- 521
- Human Metabolome Database ID
- HMDB0014771
- InChI
- InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)/t11-/m0/s1
- InChIKey
- CUHVIMMYOGQXCV-NSHDSACASA-N
- MeSH concept ID
- M0140432
- MeSH descriptor ID
- D020927
- MeSH tree code
- D03.383.129.308.245
- Microsoft Academic ID (discontinued)
- 2781302539
- NDF-RT ID
- N0000148660
- PDB ligand ID
- CZX
- Probes And Drugs ID
- PD009878
- PubChem CID
- 5311068
- Reaxys registry number
- 5906875
- RxNorm CUI
- 48937
- UNII
- 67VB76HONO
- UniChem compound ID
- 451012
- WikiProjectMed ID
- Dexmedetomidine
- YSO ID
- 16161
🔗 Connections
Significant drug interaction 32
← Significant drug interaction 32
Has use 1
Medical condition treated 1
Subclass of 1
← Drug or therapy used for treatment 1
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Summary
dexmedetomidine is a type of chemical entity[1].
Key Facts
- Physically interacts with: Adrenoceptor alpha 2A[2], Adrenoceptor alpha 2B[3], Adrenoceptor alpha 2C[4]
- Canonical SMILES: CC1=C(C(=CC=C1)C(C)C2=CN=CN2)C[5]
- Chemical formula: C₁₃H₁₆N₂[6]
- Subclass of: medetomidine[7]
- Has use: medication[8]
- Significant drug interaction: pethidine[9], periciazine[10], tramadol[11], (RS)-methadone[12], morphine[13], oxycodone[14], hydromorphone[15], dihydrocodeine[16], codeine[17], tapentadol[18], buprenorphine[19], fentanyl[20], alfentanil[21], sufentanil[22]
- Isomeric SMILES: CC1=C(C(=CC=C1)C@HC2=CN=CN2)CC@HC2=CN=CN2)C">[23]
- Mass: 200.131349 dalton[24]
- Medical condition treated: pain[25], agitation in dementia[26]
- World Health Organisation international non-proprietary name: dexmedetomidine[27]
- Subject has role: non-opioid analgesic[28], Adrenergic alpha-2 Receptor Agonists[29], hypnotics and sedatives[30]
- Stereoisomer of: levomedetomidine[31]
- Pregnancy category: US pregnancy category C[32]