Caspase 4
mammalian protein found in Homo sapiens
Facts
8 properties- Instance of
- protein
- Biological process
- regulation of apoptotic process, programmed cell death, immune system process, proteolysis, intrinsic apoptotic signaling pathway, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, regulation of inflammatory response, innate immune response, inflammatory response, cellular response to amyloid-beta, apoptotic process, execution phase of apoptosis, positive regulation of tumor necrosis factor-mediated signaling pathway, execution phase of apoptosis, apoptotic process, activation of cysteine-type endopeptidase activity involved in apoptotic process[25][26][27][28][29][30][31][32][33][34][35][36][37][38]
- Cell component
- NLRP3 inflammasome complex, cytoplasm, endoplasmic reticulum membrane, membrane, extracellular region, AIM2 inflammasome complex, IPAF inflammasome complex, endoplasmic reticulum, mitochondrion, inflammasome complex, cytosol, plasma membrane, protein-containing complex, cytoplasm[12][13][14][15][16][17][18][19][20][21][22][23][24]
- EC enzyme number
- 3.4.22.57[2]
- Found in taxon
- Homo sapiens[40]
- Molecular function
- cysteine-type peptidase activity, peptidase activity, hydrolase activity, cysteine-type endopeptidase activity involved in execution phase of apoptosis, cysteine-type endopeptidase activity involved in apoptotic process, cysteine-type endopeptidase activity, CARD domain binding, cysteine-type endopeptidase activity, cysteine-type endopeptidase activity involved in apoptotic signaling pathway, protein binding[3][4][5][6][7][8][9][10][11]
- Physically interacts with
- emricasan[1]
🏷️ Also known as
en apoptotic cysteine protease Mih1/TX
en CASP-4
en CASP4
en caspase-4
en Caspase 4
en caspase 4, apoptosis-related cysteine peptidase
en caspase 4, apoptosis-related cysteine protease
en ICE and Ced-3 homolog 2
en ICE(rel)-II
en ICH-2
en Mih1
en protease ICH-2
en protease TX
fa کاسپاز ۴
ja カスパーゼ-4
ko 캐스페이스 4
zh 胱天蛋白酶4
🔖 Identifiers · 5
- Ensembl protein ID
- ENSP00000376857, ENSP00000388566, ENSP00000401673, ENSP00000432879
- Freebase ID
- /m/02qxl7s
- Microsoft Academic ID (discontinued)
- 2779407989
- RefSeq protein ID
- NP_001216, NP_150649, XP_011541321, XP_016873886
- UniProt protein ID
- P49662
🔗 Connections
Cell component 7
Biological process 5
Found in taxon 1
Instance of 1
Molecular function 1
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