thioredoxin reductase 2

mammalian protein found in Homo sapiens
Protein protein Q21125517
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thioredoxin reductase 2

Summary

thioredoxin reductase 2 is a protein[1].

Key Facts

  • thioredoxin reductase 2's instance of is recorded as protein[2].
  • thioredoxin reductase 2 is part of FAD/NAD-linked reductase, dimerisation domain superfamily[3].
  • thioredoxin reductase 2 is part of Thioredoxin/glutathione reductase selenoprotein[4].
  • thioredoxin reductase 2 is part of FAD/NAD(P)-binding domain superfamily[5].
  • thioredoxin reductase 2 is part of FAD/NAD(P)-binding domain, protein family[6].
  • thioredoxin reductase 2 is part of Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain, protein family[7].
  • thioredoxin reductase 2 is part of Pyridine nucleotide-disulphide oxidoreductase, class I, active site, protein family[8].
  • thioredoxin reductase 2 comprises Pyridine nucleotide-disulphide oxidoreductase, class I, active site[9].
  • thioredoxin reductase 2 comprises FAD/NAD(P)-binding domain[10].
  • thioredoxin reductase 2 comprises Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain[11].
  • thioredoxin reductase 2's molecular function is recorded as oxidoreductase activity[12].
  • thioredoxin reductase 2's molecular function is recorded as protein binding[13].
  • thioredoxin reductase 2's molecular function is recorded as oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor[14].
  • thioredoxin reductase 2's molecular function is recorded as flavin adenine dinucleotide binding[15].
  • thioredoxin reductase 2's molecular function is recorded as thioredoxin-disulfide reductase activity[16].
  • thioredoxin reductase 2's molecular function is recorded as electron transfer activity[17].
  • thioredoxin reductase 2's molecular function is recorded as thioredoxin-disulfide reductase activity[18].
  • thioredoxin reductase 2's cell component is recorded as mitochondrial matrix[19].
  • thioredoxin reductase 2's cell component is recorded as mitochondrion[20].
  • thioredoxin reductase 2's cell component is recorded as cytosol[21].
  • thioredoxin reductase 2's cell component is recorded as cytoplasm[22].
  • thioredoxin reductase 2's cell component is recorded as mitochondrion[23].
  • thioredoxin reductase 2's biological process is recorded as response to oxygen radical[24].
  • thioredoxin reductase 2's biological process is recorded as cellular oxidant detoxification[25].
  • thioredoxin reductase 2's biological process is recorded as cell redox homeostasis[26].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] . Q905695. Retrieved . wikidata.org.
  2. [3] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [4] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [5] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [6] . wikidata.org.
  6. [7] . wikidata.org.
  7. [8] . wikidata.org.
  8. [9] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  9. [10] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  10. [11] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  11. [12] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [13] . Human ADA3 regulates RARalpha transcriptional activity through direct contact between LxxLL motifs and the receptor coactivator pocket. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] . Cloning, sequencing and functional expression of a novel human thioredoxin reductase. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] . Cloning, sequencing and functional expression of a novel human thioredoxin reductase. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [23] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [24] . Redox regulation of cell signaling by selenocysteine in mammalian thioredoxin reductases. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [25] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [26] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). thioredoxin reductase 2. Retrieved May 3, 2026, from https://4ort.xyz/entity/thioredoxin-reductase-2
MLA “thioredoxin reductase 2.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/thioredoxin-reductase-2.
BibTeX @misc{4ortxyz_thioredoxin-reductase-2_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{thioredoxin reductase 2}}, year = {2026}, url = {https://4ort.xyz/entity/thioredoxin-reductase-2}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): thioredoxin reductase 2 — https://4ort.xyz/entity/thioredoxin-reductase-2 (retrieved 2026-05-03)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 4d ago · Boghog · 2026-07-24 view diff on Wikidata ↗
    Found in taxon Homo sapiens
    Mesh tree code D08.811.682.667.750.750
    Wikidata description mammalian protein found in Homo sapiens
    Pdb structure id 1W1E
    + 14 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ [[Property:P591]]: 1.8.1.9, [[:toollabs:quickstatements/#/batch/261491|batch #261491]]"
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