substance P

neuropeptide in human, associated with pain
ChemicalSubstance type_of_chemical_entity Q411041
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substance P

Summary

substance P is a type of chemical entity[1]. It ranks in the top 5% of type_of_chemical_entity entities by monthly Wikipedia readership (23 views/month).[2]

Key Facts

  • substance P's instance of is recorded as type of chemical entity[3].
  • substance P's physically interacts with is recorded as Tachykinin receptor 1[4].
  • substance P's physically interacts with is recorded as Tachykinin receptor 2[5].
  • substance P's physically interacts with is recorded as Tachykinin receptor 3[6].
  • substance P's physically interacts with is recorded as Tachykinin receptor 3[7].
  • substance P's canonical SMILES is recorded as CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CNC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(CCC(=O)N)NC(=O)C(CCC(=O)N)NC(=O)C3CCCN3C(=O)C(CCCCN)NC(=O)C4CCCN4C(=O)C(CCCN=C(N)N)N[8].
  • substance P's chemical formula is recorded as C₆₃H₉₈N₁₈O₁₃S[9].
  • substance P is a type of peptide[10].
  • substance P is part of G alpha (q) signalling events[11].
  • substance P is part of Tachykinin receptors bind tachykinins[12].
  • substance P is part of substance P catabolic process[13].
  • substance P is part of Tachykinin precursor 1[14].
  • substance P comprises nitrogen[15].
  • substance P comprises carbon[16].
  • substance P's molecular function is recorded as substance P receptor binding[17].
  • substance P's molecular function is recorded as substance P receptor binding[18].
  • substance P's encoded by is recorded as TAC1[19].
  • substance P's found in taxon is recorded as Homo sapiens[20].
  • substance P's isomeric SMILES is recorded as CC(C)CC@@HNC(=O)CNC(=O)C@HNC(=O)C@HNC(=O)C@HNC(=O)C@HNC(=O)[C@@H]3CCCN3C(=O)C@HNC(=O)[C@@H]4CCCN4C(=O)C@HNC@@HNC(=O)CNC(=O)C@HNC(=O)C@HNC(=O)C@HNC(=O)C@HNC(=O)[C@@H]3CCCN3C(=O)[">[21].
  • substance P's mass is recorded as {'unit': 'Q483261', 'amount': '+1346.728146'}[22].
  • substance P's subject has role is recorded as neurotransmitter[23].
  • substance P's subject has role is recorded as protein fragment[24].
  • substance P's subject has role is recorded as neuropeptide[25].
  • substance P's subject has role is recorded as tachykinins[26].
  • substance P's exact match is recorded as https://www.uniprot.org/uniprot/P20366#PRO_0000033530[27].

Why It Matters

substance P ranks in the top 5% of type_of_chemical_entity entities by monthly Wikipedia readership (23 views/month).[2] It has Wikipedia articles in 17 language editions, a strong signal of global cultural recognition.[28] It is known by 15 alternative names across languages and contexts.[29]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] . wikidata.org.
  2. [4] . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  3. [5] . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  4. [6] . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  5. [7] . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  6. [8] . PubChem. Retrieved . wikidata.org.
  7. [9] . PubChem. Retrieved . wikidata.org.
  8. [10] . wikidata.org.
  9. [11] . wikidata.org.
  10. [12] . wikidata.org.
  11. [13] . Gene Ontology release 2019-11-16. wikidata.org.
  12. [14] . wikidata.org.
  13. [15] . wikidata.org.
  14. [16] . wikidata.org.
  15. [17] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] . wikidata.org.
  18. [20] . wikidata.org.
  19. [21] . PubChem. Retrieved . wikidata.org.
  20. [22] . PubChem. Retrieved . wikidata.org.
  21. [23] . Medical Subject Headings. Retrieved . wikidata.org.
  22. [24] . Q905695. wikidata.org.
  23. [25] . IUPHAR/BPS Guide to PHARMACOLOGY. wikidata.org.
  24. [26] . wikidata.org.
  25. [27] . wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] . Wikimedia Foundation. dumps.wikimedia.org.
  2. [28] . Wikidata sitelinks. wikidata.org.
  3. [29] . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). substance P. Retrieved May 3, 2026, from https://4ort.xyz/entity/substance-p
MLA “substance P.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/substance-p.
BibTeX @misc{4ortxyz_substance-p_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{substance P}}, year = {2026}, url = {https://4ort.xyz/entity/substance-p}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): substance P — https://4ort.xyz/entity/substance-p (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/substance-p · Last refreshed:

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 7d ago · Twofivesixbot bot · 2026-05-25 view diff on Wikidata ↗
    Part of
    Unii 675VGV5J1D
    Instance of
    Subclass of peptide
    + 13 other properties edited (see Wikidata diff for full list)
    "/* wbsetclaim-update-qualifiers:1||1|2 */ [[Property:P8189]]: 987007543736105171, mv to monolingual text names on J9U statements"
Live feed via Wikidata EventStreams. New edits appear within minutes of being made on Wikidata.