sirolimus

Immunosuppressive medicine used to prevent rejection of transplanted organs
ChemicalSubstance type_of_chemical_entity Q32089
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sirolimus

Summary

sirolimus is a type of chemical entity[1]. sirolimus ranks in the top 3% of type_of_chemical_entity entities by monthly Wikipedia readership (2,045 views/month).[2]

Key Facts

  • sirolimus's instance of is recorded as type of chemical entity[3].
  • sirolimus's physically interacts with is recorded as FKBP prolyl isomerase 1A[4].
  • sirolimus's canonical SMILES is recorded as CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)O)C)C)O)OC)C)C)C)OC[5].
  • sirolimus's chemical formula is recorded as C₅₁H₇₉NO₁₃[6].
  • sirolimus is a type of alkaloid[7].
  • sirolimus is a type of (32RS)-rapamycin[8].
  • sirolimus is part of cellular response to rapamycin[9].
  • sirolimus is part of response to rapamycin[10].
  • sirolimus is used for medication[11].
  • sirolimus is used for chemical probe[12].
  • sirolimus is used for biological research[13].
  • sirolimus's Commons category is recorded as Sirolimus[14].
  • sirolimus comprises carbon[15].
  • sirolimus comprises hydrogen[16].
  • sirolimus comprises oxygen[17].
  • sirolimus comprises nitrogen[18].
  • sirolimus's route of administration is recorded as intraperitoneal injection[19].
  • sirolimus's route of administration is recorded as oral administration[20].
  • sirolimus's route of administration is recorded as intravenous infusion and defusionههبهلخل[21].
  • sirolimus's found in taxon is recorded as Streptomyces hygroscopicus[22].
  • sirolimus's found in taxon is recorded as Streptomyces iranensis[23].
  • sirolimus's found in taxon is recorded as Streptomyces rapamycinicus[24].
  • sirolimus's found in taxon is recorded as Purpureocillium[25].
  • sirolimus's found in taxon is recorded as Ophiocordyceps[26].
  • sirolimus's significant drug interaction is recorded as diltiazem[27].

Why It Matters

sirolimus ranks in the top 3% of type_of_chemical_entity entities by monthly Wikipedia readership (2,045 views/month).[2] sirolimus has Wikipedia articles in 22 language editions, a strong signal of global cultural recognition.[28] sirolimus is known by 31 alternative names across languages and contexts.[29]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] . wikidata.org.
  2. [4] . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  3. [5] . PubChem. Retrieved . wikidata.org.
  4. [6] . PubChem. Retrieved . wikidata.org.
  5. [7] . wikidata.org.
  6. [8] . wikidata.org.
  7. [9] . Gene Ontology release 2019-11-16. wikidata.org.
  8. [10] . Gene Ontology release 2019-11-16. wikidata.org.
  9. [11] . DrugBank. Retrieved . newscientist.com. Provenance: wikidata.org.
  10. [12] . wikidata.org.
  11. [13] . wikidata.org.
  12. [14] . wikidata.org.
  13. [15] . wikidata.org.
  14. [16] . wikidata.org.
  15. [17] . wikidata.org.
  16. [18] . wikidata.org.
  17. [19] . wikidata.org.
  18. [20] . wikidata.org.
  19. [21] . wikidata.org.
  20. [22] . Incorporation of acetate, propionate, and methionine into rapamycin by Streptomyces hygroscopicus. wikidata.org.
  21. [23] . Secretion of FK506/FK520 and rapamycin by Streptomyces inhibits the growth of competing Saccharomyces cerevisiae and Cryptococcus neoformans. wikidata.org.
  22. [24] . Secretion of FK506/FK520 and rapamycin by Streptomyces inhibits the growth of competing Saccharomyces cerevisiae and Cryptococcus neoformans. wikidata.org.
  23. [25] . Leucinostatins from Ophiocordyceps spp. and Purpureocillium spp. Demonstrate Selective Antiproliferative Effects in Cells Representing the Luminal Androgen Receptor Subtype of Triple Negative Breast Cancer. wikidata.org.
  24. [26] . Leucinostatins from Ophiocordyceps spp. and Purpureocillium spp. Demonstrate Selective Antiproliferative Effects in Cells Representing the Luminal Androgen Receptor Subtype of Triple Negative Breast Cancer. wikidata.org.
  25. [27] . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] . Wikimedia Foundation. dumps.wikimedia.org.
  2. [28] . Wikidata sitelinks. wikidata.org.
  3. [29] . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). sirolimus. Retrieved May 3, 2026, from https://4ort.xyz/entity/sirolimus
MLA “sirolimus.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/sirolimus.
BibTeX @misc{4ortxyz_sirolimus_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{sirolimus}}, year = {2026}, url = {https://4ort.xyz/entity/sirolimus}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): sirolimus — https://4ort.xyz/entity/sirolimus (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/sirolimus · Last refreshed:

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 7d ago · Twofivesixbot bot · 2026-05-23 view diff on Wikidata ↗
    Described at url https://www.newscientist.com/article/2516893-rapamycin-can-a
    "/* wbsetclaim-update-qualifiers:1||1|7 */ [[Property:P8189]]: 987007542160305171, mv to monolingual text names on J9U statements"
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