Signal transducer and activator of transcription 5B

mammalian protein found in Mus musculus

Protein protein Q21495226

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Signal transducer and activator of transcription 5B

Summary

Signal transducer and activator of transcription 5B is a protein^[1].

Key Facts

Signal transducer and activator of transcription 5B's instance of is recorded as protein^[2].
Signal transducer and activator of transcription 5B's subclass of is recorded as protein^[3].
Signal transducer and activator of transcription 5B's UniProt protein ID is recorded as P42232^[4].
Signal transducer and activator of transcription 5B's part of is recorded as p53-like transcription factor, DNA-binding^[5].
Signal transducer and activator of transcription 5B's part of is recorded as STAT5^[6].
Signal transducer and activator of transcription 5B's part of is recorded as STAT transcription factor, DNA-binding, N-terminal^[7].
Signal transducer and activator of transcription 5B's part of is recorded as STAT transcription factor, coiled coil^[8].
Signal transducer and activator of transcription 5B's part of is recorded as SH2 domain superfamily^[9].
Signal transducer and activator of transcription 5B's part of is recorded as STAT transcription factor, N-terminal domain superfamily^[10].
Signal transducer and activator of transcription 5B's part of is recorded as STAT transcription factor, protein interaction, protein family^[11].
Signal transducer and activator of transcription 5B's part of is recorded as SH2 domain, protein family^[12].
Signal transducer and activator of transcription 5B's part of is recorded as STAT transcription factor, DNA-binding domain, protein family^[13].
Signal transducer and activator of transcription 5B's part of is recorded as STAT5b, SH2 domain, protein family^[14].
Signal transducer and activator of transcription 5B's part of is recorded as STAT transcription factor, all-alpha domain, protein family^[15].
Signal transducer and activator of transcription 5B's has part is recorded as STAT transcription factor, DNA-binding^[16].
Signal transducer and activator of transcription 5B's has part is recorded as SH2 domain^[17].
Signal transducer and activator of transcription 5B's has part is recorded as STAT transcription factor, all-alpha domain^[18].
Signal transducer and activator of transcription 5B's has part is recorded as STAT transcription factor, protein interaction^[19].
Signal transducer and activator of transcription 5B's has part is recorded as STAT5b, SH2 domain^[20].
Signal transducer and activator of transcription 5B's RefSeq protein ID is recorded as NP_001107035^[21].
Signal transducer and activator of transcription 5B's RefSeq protein ID is recorded as NP_035619^[22].
Signal transducer and activator of transcription 5B's RefSeq protein ID is recorded as NP_001349611^[23].
Signal transducer and activator of transcription 5B's molecular function is recorded as protein dimerization activity^[24].
Signal transducer and activator of transcription 5B's molecular function is recorded as DNA-binding transcription activator activity, RNA polymerase II-specific^[25].
Signal transducer and activator of transcription 5B's molecular function is recorded as protein binding^[26].

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Quick Facts

Instance of protein

Subclass of protein

Part of p53-like transcription factor, DNA-binding, STAT5, STAT transcription factor, DNA-binding, N-terminal, STAT transcription factor, coiled coil, SH2 domain superfamily, STAT transcription factor, N-terminal domain superfamily, STAT transcription factor, protein interaction, protein family, SH2 domain, protein family, STAT transcription factor, DNA-binding domain, protein family, STAT5b, SH2 domain, protein family, STAT transcription factor, all-alpha domain, protein family

Properties

Biological process response to estradiol, positive regulation of inflammatory response, response to interleukin-15, allantoin metabolic process, positive regulation of natural killer cell differentiation, T cell differentiation in thymus, response to interleukin-4, regulation of multicellular organism growth, cytokine-mediated signaling pathway, progesterone metabolic process, citrate metabolic process, regulation of transcription by RNA polymerase II, positive regulation of B cell differentiation, female pregnancy, response to interleukin-2, cellular response to growth factor stimulus, lipid storage, positive regulation of mitotic cell cycle, sex differentiation, negative regulation of apoptotic process, 2-oxoglutarate metabolic process, creatinine metabolic process, oxaloacetate metabolic process, transcription, DNA-templated, fatty acid metabolic process, negative regulation of erythrocyte differentiation, T cell homeostasis, regulation of steroid metabolic process, positive regulation of natural killer cell proliferation, succinate metabolic process, cellular response to hormone stimulus, regulation of cell adhesion, positive regulation of lymphocyte differentiation, taurine metabolic process, valine metabolic process, development of secondary male sexual characteristics, mast cell migration, positive regulation of cell population proliferation, positive regulation of multicellular organism growth, creatine metabolic process, Peyer's patch development, lactation, regulation of epithelial cell differentiation, isoleucine metabolic process, positive regulation of gamma-delta T cell differentiation, positive regulation of natural killer cell mediated cytotoxicity, signal transduction, positive regulation of activated T cell proliferation, positive regulation of transcription by RNA polymerase II, development of secondary female sexual characteristics, natural killer cell differentiation, positive regulation of erythrocyte differentiation, growth hormone receptor signaling pathway via JAK-STAT, luteinization, liver development, regulation of transcription, DNA-templated, transcription by RNA polymerase II, acute-phase response, receptor signaling pathway via JAK-STAT, response to lipopolysaccharide, response to peptide hormone, positive regulation of smooth muscle cell proliferation, cellular response to epidermal growth factor stimulus, taurine metabolic process, regulation of multicellular organism growth, defense response, receptor signaling pathway via JAK-STAT, cytokine-mediated signaling pathway, regulation of cell population proliferation, response to peptide hormone, positive regulation of transcription by RNA polymerase II, growth hormone receptor signaling pathway via JAK-STAT

Cell component cytoplasm, nucleoplasm, nucleus, cytosol, nucleus, cytosol

Encoded by Stat5b

Found in taxon house mouse

Has part(s) STAT transcription factor, DNA-binding, SH2 domain, STAT transcription factor, all-alpha domain, STAT transcription factor, protein interaction, STAT5b, SH2 domain

Imported from wholeness_audit_2026-05-02

Molecular function protein dimerization activity, DNA-binding transcription activator activity, RNA polymerase II-specific, protein binding, glucocorticoid receptor binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA binding, chromatin binding, double-stranded DNA binding, DNA-binding transcription factor activity, signal transducer activity, sequence-specific DNA binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific

External References (3)

Ensembl protein id ENSMUSP00000004143, ENSMUSP00000102981

Refseq protein id NP_001107035, NP_035619, NP_001349611

Uniprot protein id P42232

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Signal transducer and activator of transcription 5B — instance of (P31): protein. Q905695. Retrieved 2022-05-25. wikidata.org.
[3] ↑ Signal transducer and activator of transcription 5B — subclass of (P279): protein. Q905695. Retrieved 2017-01-19. wikidata.org.
[4] ↑ Signal transducer and activator of transcription 5B — UniProt protein ID (P352): P42232. Q905695. Retrieved 2022-05-25. wikidata.org.
[5] ↑ Signal transducer and activator of transcription 5B — part of (P361): p53-like transcription factor, DNA-binding. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Signal transducer and activator of transcription 5B — part of (P361): STAT5. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Signal transducer and activator of transcription 5B — part of (P361): STAT transcription factor, DNA-binding, N-terminal. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Signal transducer and activator of transcription 5B — part of (P361): STAT transcription factor, coiled coil. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[9] ↑ Signal transducer and activator of transcription 5B — part of (P361): SH2 domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[10] ↑ Signal transducer and activator of transcription 5B — part of (P361): STAT transcription factor, N-terminal domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[11] ↑ Signal transducer and activator of transcription 5B — part of (P361): STAT transcription factor, protein interaction, protein family. wikidata.org.
[12] ↑ Signal transducer and activator of transcription 5B — part of (P361): SH2 domain, protein family. wikidata.org.
[13] ↑ Signal transducer and activator of transcription 5B — part of (P361): STAT transcription factor, DNA-binding domain, protein family. wikidata.org.
[14] ↑ Signal transducer and activator of transcription 5B — part of (P361): STAT5b, SH2 domain, protein family. wikidata.org.
[15] ↑ Signal transducer and activator of transcription 5B — part of (P361): STAT transcription factor, all-alpha domain, protein family. wikidata.org.
[16] ↑ Signal transducer and activator of transcription 5B — has part(s) (P527): STAT transcription factor, DNA-binding. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Signal transducer and activator of transcription 5B — has part(s) (P527): SH2 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Signal transducer and activator of transcription 5B — has part(s) (P527): STAT transcription factor, all-alpha domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ Signal transducer and activator of transcription 5B — has part(s) (P527): STAT transcription factor, protein interaction. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ Signal transducer and activator of transcription 5B — has part(s) (P527): STAT5b, SH2 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ Signal transducer and activator of transcription 5B — RefSeq protein ID (P637): NP_001107035. Q20641742. Retrieved 2022-03-20. wikidata.org.
[22] ↑ Signal transducer and activator of transcription 5B — RefSeq protein ID (P637): NP_035619. Q20641742. Retrieved 2022-03-20. wikidata.org.
[23] ↑ Signal transducer and activator of transcription 5B — RefSeq protein ID (P637): NP_001349611. Q20641742. Retrieved 2022-03-20. wikidata.org.
[24] ↑ Signal transducer and activator of transcription 5B — molecular function (P680): protein dimerization activity. A novel role of CPEB3 in regulating EGFR gene transcription via association with Stat5b in neurons. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ Signal transducer and activator of transcription 5B — molecular function (P680): DNA-binding transcription activator activity, RNA polymerase II-specific. IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells. Retrieved 2018-04-24. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ Signal transducer and activator of transcription 5B — molecular function (P680): protein binding. A novel role of CPEB3 in regulating EGFR gene transcription via association with Stat5b in neurons. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Signal transducer and activator of transcription 5B is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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APA

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MLA

“Signal transducer and activator of transcription 5B.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/signal-transducer-and-activator-of-transcription-5b-q21495226.

BibTeX

@misc{4ortxyz_signal-transducer-and-activator-of-transcription-5b-q21495226_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Signal transducer and activator of transcription 5B}}, year = {2026}, url = {https://4ort.xyz/entity/signal-transducer-and-activator-of-transcription-5b-q21495226}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Signal transducer and activator of transcription 5B — https://4ort.xyz/entity/signal-transducer-and-activator-of-transcription-5b-q21495226 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/signal-transducer-and-activator-of-transcription-5b-q21495226 · Last refreshed: May 3, 2026