Signal transducer and activator of transcription 5B

mammalian protein found in Homo sapiens

Protein protein Q21141761

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Signal transducer and activator of transcription 5B

Summary

Signal transducer and activator of transcription 5B is a protein^[1].

Key Facts

Signal transducer and activator of transcription 5B's instance of is recorded as protein^[2].
Signal transducer and activator of transcription 5B's subclass of is recorded as protein^[3].
Signal transducer and activator of transcription 5B's UniProt protein ID is recorded as P51692^[4].
Signal transducer and activator of transcription 5B's part of is recorded as p53-like transcription factor, DNA-binding^[5].
Signal transducer and activator of transcription 5B's part of is recorded as STAT5^[6].
Signal transducer and activator of transcription 5B's part of is recorded as STAT transcription factor, DNA-binding, N-terminal^[7].
Signal transducer and activator of transcription 5B's part of is recorded as STAT transcription factor, coiled coil^[8].
Signal transducer and activator of transcription 5B's part of is recorded as SH2 domain superfamily^[9].
Signal transducer and activator of transcription 5B's part of is recorded as STAT transcription factor, N-terminal domain superfamily^[10].
Signal transducer and activator of transcription 5B's part of is recorded as STAT transcription factor, protein interaction, protein family^[11].
Signal transducer and activator of transcription 5B's part of is recorded as SH2 domain, protein family^[12].
Signal transducer and activator of transcription 5B's part of is recorded as STAT transcription factor, DNA-binding domain, protein family^[13].
Signal transducer and activator of transcription 5B's part of is recorded as STAT5b, SH2 domain, protein family^[14].
Signal transducer and activator of transcription 5B's part of is recorded as STAT transcription factor, all-alpha domain, protein family^[15].
Signal transducer and activator of transcription 5B's has part is recorded as SH2 domain^[16].
Signal transducer and activator of transcription 5B's has part is recorded as STAT transcription factor, all-alpha domain^[17].
Signal transducer and activator of transcription 5B's has part is recorded as STAT transcription factor, DNA-binding^[18].
Signal transducer and activator of transcription 5B's has part is recorded as STAT transcription factor, protein interaction^[19].
Signal transducer and activator of transcription 5B's has part is recorded as STAT5b, SH2 domain^[20].
Signal transducer and activator of transcription 5B's RefSeq protein ID is recorded as NP_036580^[21].
Signal transducer and activator of transcription 5B's RefSeq protein ID is recorded as XP_005257683^[22].
Signal transducer and activator of transcription 5B's RefSeq protein ID is recorded as XP_016880466^[23].
Signal transducer and activator of transcription 5B's RefSeq protein ID is recorded as XP_024306665^[24].
Signal transducer and activator of transcription 5B's RefSeq protein ID is recorded as XP_024306666^[25].
Signal transducer and activator of transcription 5B's molecular function is recorded as signal transducer activity^[26].

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Quick Facts

Instance of protein

Subclass of protein

Part of p53-like transcription factor, DNA-binding, STAT5, STAT transcription factor, DNA-binding, N-terminal, STAT transcription factor, coiled coil, SH2 domain superfamily, STAT transcription factor, N-terminal domain superfamily, STAT transcription factor, protein interaction, protein family, SH2 domain, protein family, STAT transcription factor, DNA-binding domain, protein family, STAT5b, SH2 domain, protein family, STAT transcription factor, all-alpha domain, protein family

Properties

Biological process positive regulation of natural killer cell differentiation, positive regulation of natural killer cell mediated cytotoxicity, regulation of steroid metabolic process, creatinine metabolic process, T cell differentiation in thymus, female pregnancy, cellular response to hormone stimulus, positive regulation of activated T cell proliferation, progesterone metabolic process, receptor signaling pathway via JAK-STAT, negative regulation of apoptotic process, Peyer's patch development, transcription, DNA-templated, signal transduction, cellular response to growth factor stimulus, natural killer cell differentiation, response to interleukin-4, sex differentiation, valine metabolic process, positive regulation of B cell differentiation, T cell homeostasis, creatine metabolic process, cellular response to epidermal growth factor stimulus, response to estradiol, positive regulation of inflammatory response, regulation of transcription by RNA polymerase II, mast cell migration, positive regulation of mitotic cell cycle, lipid storage, development of secondary female sexual characteristics, fatty acid metabolic process, taurine metabolic process, succinate metabolic process, positive regulation of gamma-delta T cell differentiation, positive regulation of lymphocyte differentiation, regulation of multicellular organism growth, citrate metabolic process, positive regulation of cell population proliferation, oxaloacetate metabolic process, regulation of epithelial cell differentiation, positive regulation of natural killer cell proliferation, development of secondary male sexual characteristics, positive regulation of multicellular organism growth, regulation of transcription, DNA-templated, allantoin metabolic process, positive regulation of transcription by RNA polymerase II, transcription by RNA polymerase II, luteinization, isoleucine metabolic process, negative regulation of erythrocyte differentiation, lactation, response to interleukin-15, regulation of cell adhesion, 2-oxoglutarate metabolic process, response to interleukin-2, growth hormone receptor signaling pathway via JAK-STAT, positive regulation of erythrocyte differentiation, peptidyl-tyrosine phosphorylation, interleukin-7-mediated signaling pathway, interleukin-15-mediated signaling pathway, cytokine-mediated signaling pathway, interleukin-2-mediated signaling pathway, interleukin-9-mediated signaling pathway, defense response, receptor signaling pathway via JAK-STAT, cytokine-mediated signaling pathway, regulation of cell population proliferation, response to peptide hormone, positive regulation of transcription by RNA polymerase II, growth hormone receptor signaling pathway via JAK-STAT

Cell component nucleoplasm, cytoplasm, nucleus, cytosol, nucleus, cytosol

Encoded by STAT5B

Found in taxon Homo sapiens

Has part(s) SH2 domain, STAT transcription factor, all-alpha domain, STAT transcription factor, DNA-binding, STAT transcription factor, protein interaction, STAT5b, SH2 domain

Imported from wholeness_audit_2026-05-02

Molecular function signal transducer activity, glucocorticoid receptor binding, protein dimerization activity, chromatin binding, DNA-binding transcription factor activity, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, protein binding, protein tyrosine kinase activity, RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific

External References (3)

Ensembl protein id ENSP00000293328, ENSP00000398379

Refseq protein id NP_036580, XP_005257683, XP_016880466, XP_024306665, XP_024306666

Uniprot protein id P51692

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Signal transducer and activator of transcription 5B — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ Signal transducer and activator of transcription 5B — subclass of (P279): protein. Q905695. Retrieved 2016-12-01. wikidata.org.
[4] ↑ Signal transducer and activator of transcription 5B — UniProt protein ID (P352): P51692. Q905695. Retrieved 2019-11-13. wikidata.org.
[5] ↑ Signal transducer and activator of transcription 5B — part of (P361): p53-like transcription factor, DNA-binding. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Signal transducer and activator of transcription 5B — part of (P361): STAT5. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Signal transducer and activator of transcription 5B — part of (P361): STAT transcription factor, DNA-binding, N-terminal. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Signal transducer and activator of transcription 5B — part of (P361): STAT transcription factor, coiled coil. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[9] ↑ Signal transducer and activator of transcription 5B — part of (P361): SH2 domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[10] ↑ Signal transducer and activator of transcription 5B — part of (P361): STAT transcription factor, N-terminal domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[11] ↑ Signal transducer and activator of transcription 5B — part of (P361): STAT transcription factor, protein interaction, protein family. wikidata.org.
[12] ↑ Signal transducer and activator of transcription 5B — part of (P361): SH2 domain, protein family. wikidata.org.
[13] ↑ Signal transducer and activator of transcription 5B — part of (P361): STAT transcription factor, DNA-binding domain, protein family. wikidata.org.
[14] ↑ Signal transducer and activator of transcription 5B — part of (P361): STAT5b, SH2 domain, protein family. wikidata.org.
[15] ↑ Signal transducer and activator of transcription 5B — part of (P361): STAT transcription factor, all-alpha domain, protein family. wikidata.org.
[16] ↑ Signal transducer and activator of transcription 5B — has part(s) (P527): SH2 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Signal transducer and activator of transcription 5B — has part(s) (P527): STAT transcription factor, all-alpha domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Signal transducer and activator of transcription 5B — has part(s) (P527): STAT transcription factor, DNA-binding. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ Signal transducer and activator of transcription 5B — has part(s) (P527): STAT transcription factor, protein interaction. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ Signal transducer and activator of transcription 5B — has part(s) (P527): STAT5b, SH2 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ Signal transducer and activator of transcription 5B — RefSeq protein ID (P637): NP_036580. Q20641742. Retrieved 2020-05-30. wikidata.org.
[22] ↑ Signal transducer and activator of transcription 5B — RefSeq protein ID (P637): XP_005257683. Q20641742. Retrieved 2020-05-30. wikidata.org.
[23] ↑ Signal transducer and activator of transcription 5B — RefSeq protein ID (P637): XP_016880466. Q20641742. Retrieved 2020-05-30. wikidata.org.
[24] ↑ Signal transducer and activator of transcription 5B — RefSeq protein ID (P637): XP_024306665. Q20641742. Retrieved 2020-05-30. wikidata.org.
[25] ↑ Signal transducer and activator of transcription 5B — RefSeq protein ID (P637): XP_024306666. Q20641742. Retrieved 2020-05-30. wikidata.org.
[26] ↑ Signal transducer and activator of transcription 5B — molecular function (P680): signal transducer activity. GOA. Retrieved 2018-03-27. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Signal transducer and activator of transcription 5B is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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APA

4ort.xyz Knowledge Graph. (2026). Signal transducer and activator of transcription 5B. Retrieved May 3, 2026, from https://4ort.xyz/entity/signal-transducer-and-activator-of-transcription-5b-q21141761

MLA

“Signal transducer and activator of transcription 5B.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/signal-transducer-and-activator-of-transcription-5b-q21141761.

BibTeX

@misc{4ortxyz_signal-transducer-and-activator-of-transcription-5b-q21141761_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Signal transducer and activator of transcription 5B}}, year = {2026}, url = {https://4ort.xyz/entity/signal-transducer-and-activator-of-transcription-5b-q21141761}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Signal transducer and activator of transcription 5B — https://4ort.xyz/entity/signal-transducer-and-activator-of-transcription-5b-q21141761 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/signal-transducer-and-activator-of-transcription-5b-q21141761 · Last refreshed: May 3, 2026