Signal transducer and activator of transcription 5A

mammalian protein found in Homo sapiens

Protein protein Q21154923

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Signal transducer and activator of transcription 5A

Summary

Signal transducer and activator of transcription 5A is a protein^[1].

Key Facts

Signal transducer and activator of transcription 5A's instance of is recorded as protein^[2].
Signal transducer and activator of transcription 5A's subclass of is recorded as protein^[3].
Signal transducer and activator of transcription 5A's UniProt protein ID is recorded as P42229^[4].
Signal transducer and activator of transcription 5A's part of is recorded as p53-like transcription factor, DNA-binding^[5].
Signal transducer and activator of transcription 5A's part of is recorded as STAT5^[6].
Signal transducer and activator of transcription 5A's part of is recorded as STAT transcription factor, DNA-binding, N-terminal^[7].
Signal transducer and activator of transcription 5A's part of is recorded as STAT transcription factor, coiled coil^[8].
Signal transducer and activator of transcription 5A's part of is recorded as SH2 domain superfamily^[9].
Signal transducer and activator of transcription 5A's part of is recorded as STAT transcription factor, N-terminal domain superfamily^[10].
Signal transducer and activator of transcription 5A's part of is recorded as STAT transcription factor, protein interaction, protein family^[11].
Signal transducer and activator of transcription 5A's part of is recorded as SH2 domain, protein family^[12].
Signal transducer and activator of transcription 5A's part of is recorded as STAT transcription factor, DNA-binding domain, protein family^[13].
Signal transducer and activator of transcription 5A's part of is recorded as STAT transcription factor, all-alpha domain, protein family^[14].
Signal transducer and activator of transcription 5A's has part is recorded as SH2 domain^[15].
Signal transducer and activator of transcription 5A's has part is recorded as STAT transcription factor, all-alpha domain^[16].
Signal transducer and activator of transcription 5A's has part is recorded as STAT transcription factor, DNA-binding^[17].
Signal transducer and activator of transcription 5A's has part is recorded as STAT transcription factor, protein interaction^[18].
Signal transducer and activator of transcription 5A's RefSeq protein ID is recorded as NP_001275647^[19].
Signal transducer and activator of transcription 5A's RefSeq protein ID is recorded as NP_001275648^[20].
Signal transducer and activator of transcription 5A's RefSeq protein ID is recorded as NP_001275649^[21].
Signal transducer and activator of transcription 5A's RefSeq protein ID is recorded as NP_003143^[22].
Signal transducer and activator of transcription 5A's RefSeq protein ID is recorded as XP_005257681^[23].
Signal transducer and activator of transcription 5A's PDB structure ID is recorded as 1Y1U^[24].
Signal transducer and activator of transcription 5A's molecular function is recorded as DNA binding^[25].
Signal transducer and activator of transcription 5A's molecular function is recorded as protein binding^[26].

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Quick Facts

Instance of protein

Subclass of protein

Part of p53-like transcription factor, DNA-binding, STAT5, STAT transcription factor, DNA-binding, N-terminal, STAT transcription factor, coiled coil, SH2 domain superfamily, STAT transcription factor, N-terminal domain superfamily, STAT transcription factor, protein interaction, protein family, SH2 domain, protein family, STAT transcription factor, DNA-binding domain, protein family, STAT transcription factor, all-alpha domain, protein family

Properties

Biological process creatinine metabolic process, positive regulation of endothelial cell proliferation, receptor signaling pathway via JAK-STAT, transcription, DNA-templated, signal transduction, valine metabolic process, creatine metabolic process, regulation of transcription by RNA polymerase II, positive regulation of blood vessel endothelial cell migration, fatty acid metabolic process, taurine metabolic process, succinate metabolic process, regulation of multicellular organism growth, citrate metabolic process, oxaloacetate metabolic process, regulation of transcription, DNA-templated, allantoin metabolic process, isoleucine metabolic process, lactation, 2-oxoglutarate metabolic process, peptidyl-tyrosine phosphorylation, interleukin-7-mediated signaling pathway, growth hormone receptor signaling pathway via JAK-STAT, interleukin-15-mediated signaling pathway, cytokine-mediated signaling pathway, interleukin-2-mediated signaling pathway, interleukin-9-mediated signaling pathway, reelin-mediated signaling pathway, defense response, receptor signaling pathway via JAK-STAT, cytokine-mediated signaling pathway, regulation of cell population proliferation, response to peptide hormone, positive regulation of transcription by RNA polymerase II, growth hormone receptor signaling pathway via JAK-STAT

Cell component nucleus, nucleoplasm, cytoplasm, cytosol, nucleus, cytosol

Encoded by STAT5A

Found in taxon Homo sapiens

Has part(s) SH2 domain, STAT transcription factor, all-alpha domain, STAT transcription factor, DNA-binding, STAT transcription factor, protein interaction

Imported from wholeness_audit_2026-05-02

Molecular function DNA binding, protein binding, DNA-binding transcription factor activity, protein tyrosine kinase activity, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific

External References (4)

Ensembl protein id ENSP00000341208, ENSP00000443107, ENSP00000468749, ENSP00000407327, ENSP00000464730, ENSP00000465437, ENSP00000466320

Pdb structure id 1Y1U

Refseq protein id NP_001275647, NP_001275648, NP_001275649, NP_003143, XP_005257681

Uniprot protein id P42229

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Signal transducer and activator of transcription 5A — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ Signal transducer and activator of transcription 5A — subclass of (P279): protein. Q905695. Retrieved 2016-12-01. wikidata.org.
[4] ↑ Signal transducer and activator of transcription 5A — UniProt protein ID (P352): P42229. Q905695. Retrieved 2019-11-13. wikidata.org.
[5] ↑ Signal transducer and activator of transcription 5A — part of (P361): p53-like transcription factor, DNA-binding. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Signal transducer and activator of transcription 5A — part of (P361): STAT5. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Signal transducer and activator of transcription 5A — part of (P361): STAT transcription factor, DNA-binding, N-terminal. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Signal transducer and activator of transcription 5A — part of (P361): STAT transcription factor, coiled coil. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[9] ↑ Signal transducer and activator of transcription 5A — part of (P361): SH2 domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[10] ↑ Signal transducer and activator of transcription 5A — part of (P361): STAT transcription factor, N-terminal domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[11] ↑ Signal transducer and activator of transcription 5A — part of (P361): STAT transcription factor, protein interaction, protein family. wikidata.org.
[12] ↑ Signal transducer and activator of transcription 5A — part of (P361): SH2 domain, protein family. wikidata.org.
[13] ↑ Signal transducer and activator of transcription 5A — part of (P361): STAT transcription factor, DNA-binding domain, protein family. wikidata.org.
[14] ↑ Signal transducer and activator of transcription 5A — part of (P361): STAT transcription factor, all-alpha domain, protein family. wikidata.org.
[15] ↑ Signal transducer and activator of transcription 5A — has part(s) (P527): SH2 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ Signal transducer and activator of transcription 5A — has part(s) (P527): STAT transcription factor, all-alpha domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Signal transducer and activator of transcription 5A — has part(s) (P527): STAT transcription factor, DNA-binding. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Signal transducer and activator of transcription 5A — has part(s) (P527): STAT transcription factor, protein interaction. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ Signal transducer and activator of transcription 5A — RefSeq protein ID (P637): NP_001275647. Q20641742. Retrieved 2020-05-30. wikidata.org.
[20] ↑ Signal transducer and activator of transcription 5A — RefSeq protein ID (P637): NP_001275648. Q20641742. Retrieved 2020-05-30. wikidata.org.
[21] ↑ Signal transducer and activator of transcription 5A — RefSeq protein ID (P637): NP_001275649. Q20641742. Retrieved 2020-05-30. wikidata.org.
[22] ↑ Signal transducer and activator of transcription 5A — RefSeq protein ID (P637): NP_003143. Q20641742. Retrieved 2020-05-30. wikidata.org.
[23] ↑ Signal transducer and activator of transcription 5A — RefSeq protein ID (P637): XP_005257681. Q20641742. Retrieved 2020-05-30. wikidata.org.
[24] ↑ Signal transducer and activator of transcription 5A — PDB structure ID (P638): 1Y1U. Swiss-Prot. Retrieved 2015-11-09. uniprot.org. Provenance: wikidata.org.
[25] ↑ Signal transducer and activator of transcription 5A — molecular function (P680): DNA binding. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ Signal transducer and activator of transcription 5A — molecular function (P680): protein binding. STAT5 represses BCL6 expression by binding to a regulatory region frequently mutated in lymphomas. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Signal transducer and activator of transcription 5A is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). Signal transducer and activator of transcription 5A. Retrieved May 3, 2026, from https://4ort.xyz/entity/signal-transducer-and-activator-of-transcription-5a-q21154923

MLA

“Signal transducer and activator of transcription 5A.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/signal-transducer-and-activator-of-transcription-5a-q21154923.

BibTeX

@misc{4ortxyz_signal-transducer-and-activator-of-transcription-5a-q21154923_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Signal transducer and activator of transcription 5A}}, year = {2026}, url = {https://4ort.xyz/entity/signal-transducer-and-activator-of-transcription-5a-q21154923}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Signal transducer and activator of transcription 5A — https://4ort.xyz/entity/signal-transducer-and-activator-of-transcription-5a-q21154923 (retrieved 2026-05-03)

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