Signal transducer and activator of transcription 5A

mammalian protein found in Mus musculus

Protein protein Q21498877

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Signal transducer and activator of transcription 5A

Summary

Signal transducer and activator of transcription 5A is a protein^[1].

Key Facts

Signal transducer and activator of transcription 5A's instance of is recorded as protein^[2].
Signal transducer and activator of transcription 5A's subclass of is recorded as protein^[3].
Signal transducer and activator of transcription 5A's UniProt protein ID is recorded as P42230^[4].
Signal transducer and activator of transcription 5A's part of is recorded as p53-like transcription factor, DNA-binding^[5].
Signal transducer and activator of transcription 5A's part of is recorded as STAT5^[6].
Signal transducer and activator of transcription 5A's part of is recorded as STAT transcription factor, DNA-binding, N-terminal^[7].
Signal transducer and activator of transcription 5A's part of is recorded as STAT transcription factor, coiled coil^[8].
Signal transducer and activator of transcription 5A's part of is recorded as SH2 domain superfamily^[9].
Signal transducer and activator of transcription 5A's part of is recorded as STAT transcription factor, N-terminal domain superfamily^[10].
Signal transducer and activator of transcription 5A's part of is recorded as STAT transcription factor, protein interaction, protein family^[11].
Signal transducer and activator of transcription 5A's part of is recorded as SH2 domain, protein family^[12].
Signal transducer and activator of transcription 5A's part of is recorded as STAT transcription factor, DNA-binding domain, protein family^[13].
Signal transducer and activator of transcription 5A's part of is recorded as STAT transcription factor, all-alpha domain, protein family^[14].
Signal transducer and activator of transcription 5A's has part is recorded as STAT transcription factor, DNA-binding^[15].
Signal transducer and activator of transcription 5A's has part is recorded as SH2 domain^[16].
Signal transducer and activator of transcription 5A's has part is recorded as STAT transcription factor, all-alpha domain^[17].
Signal transducer and activator of transcription 5A's has part is recorded as STAT transcription factor, protein interaction^[18].
Signal transducer and activator of transcription 5A's RefSeq protein ID is recorded as NP_001157534^[19].
Signal transducer and activator of transcription 5A's RefSeq protein ID is recorded as NP_035618^[20].
Signal transducer and activator of transcription 5A's RefSeq protein ID is recorded as XP_006532784^[21].
Signal transducer and activator of transcription 5A's RefSeq protein ID is recorded as XP_017169891^[22].
Signal transducer and activator of transcription 5A's RefSeq protein ID is recorded as NP_001349609^[23].
Signal transducer and activator of transcription 5A's PDB structure ID is recorded as 1Y1U^[24].
Signal transducer and activator of transcription 5A's molecular function is recorded as DNA binding^[25].
Signal transducer and activator of transcription 5A's molecular function is recorded as protein binding^[26].

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Quick Facts

Instance of protein

Subclass of protein

Part of p53-like transcription factor, DNA-binding, STAT5, STAT transcription factor, DNA-binding, N-terminal, STAT transcription factor, coiled coil, SH2 domain superfamily, STAT transcription factor, N-terminal domain superfamily, STAT transcription factor, protein interaction, protein family, SH2 domain, protein family, STAT transcription factor, DNA-binding domain, protein family, STAT transcription factor, all-alpha domain, protein family

Properties

Biological process luteinization, positive regulation of inflammatory response, regulation of transcription, DNA-templated, allantoin metabolic process, epithelial cell differentiation involved in prostate gland development, positive regulation of natural killer cell differentiation, T cell differentiation in thymus, mammary gland epithelium development, regulation of multicellular organism growth, cytokine-mediated signaling pathway, citrate metabolic process, regulation of transcription by RNA polymerase II, positive regulation of B cell differentiation, female pregnancy, cellular response to organic cyclic compound, lipid storage, negative regulation of mast cell apoptotic process, response to peptide hormone, positive regulation of mitotic cell cycle, negative regulation of apoptotic process, 2-oxoglutarate metabolic process, creatinine metabolic process, oxaloacetate metabolic process, transcription, DNA-templated, fatty acid metabolic process, negative regulation of erythrocyte differentiation, cellular response to cytokine stimulus, mammary gland development, T cell homeostasis, regulation of steroid metabolic process, succinate metabolic process, regulation of cell adhesion, prostate gland epithelium morphogenesis, positive regulation of lymphocyte differentiation, taurine metabolic process, positive regulation of mast cell differentiation, valine metabolic process, development of secondary male sexual characteristics, positive regulation of mast cell proliferation, cellular response to granulocyte macrophage colony-stimulating factor stimulus, positive regulation of cell population proliferation, positive regulation of multicellular organism growth, creatine metabolic process, peptidyl-tyrosine phosphorylation, Peyer's patch development, lactation, regulation of epithelial cell differentiation, isoleucine metabolic process, positive regulation of gamma-delta T cell differentiation, positive regulation of natural killer cell mediated cytotoxicity, signal transduction, positive regulation of activated T cell proliferation, positive regulation of transcription by RNA polymerase II, development of secondary female sexual characteristics, natural killer cell differentiation, positive regulation of blood vessel endothelial cell migration, positive regulation of endothelial cell proliferation, growth hormone receptor signaling pathway via JAK-STAT, transcription by RNA polymerase II, receptor signaling pathway via JAK-STAT, mammary gland involution, taurine metabolic process, reelin-mediated signaling pathway, regulation of multicellular organism growth, defense response, receptor signaling pathway via JAK-STAT, cytokine-mediated signaling pathway, regulation of cell population proliferation, response to peptide hormone, positive regulation of transcription by RNA polymerase II, growth hormone receptor signaling pathway via JAK-STAT

Cell component nucleoplasm, cytosol, nucleus, cytoplasm, nucleus, cytosol

Encoded by Stat5a

Found in taxon house mouse

Has part(s) STAT transcription factor, DNA-binding, SH2 domain, STAT transcription factor, all-alpha domain, STAT transcription factor, protein interaction

Imported from wholeness_audit_2026-05-02

Molecular function DNA binding, protein binding, DNA-binding transcription activator activity, RNA polymerase II-specific, RNA polymerase II cis-regulatory region sequence-specific DNA binding, double-stranded DNA binding, DNA-binding transcription factor activity, signal transducer activity, sequence-specific DNA binding, phosphate ion binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific

External References (4)

Ensembl protein id ENSMUSP00000004145, ENSMUSP00000102979, ENSMUSP00000102980, ENSMUSP00000117204, ENSMUSP00000120039

Pdb structure id 1Y1U

Refseq protein id NP_001157534, NP_035618, XP_006532784, XP_017169891, NP_001349609

Uniprot protein id P42230

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Signal transducer and activator of transcription 5A — instance of (P31): protein. Q905695. Retrieved 2022-05-25. wikidata.org.
[3] ↑ Signal transducer and activator of transcription 5A — subclass of (P279): protein. Q905695. Retrieved 2017-01-19. wikidata.org.
[4] ↑ Signal transducer and activator of transcription 5A — UniProt protein ID (P352): P42230. Q905695. Retrieved 2022-05-25. wikidata.org.
[5] ↑ Signal transducer and activator of transcription 5A — part of (P361): p53-like transcription factor, DNA-binding. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Signal transducer and activator of transcription 5A — part of (P361): STAT5. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Signal transducer and activator of transcription 5A — part of (P361): STAT transcription factor, DNA-binding, N-terminal. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Signal transducer and activator of transcription 5A — part of (P361): STAT transcription factor, coiled coil. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[9] ↑ Signal transducer and activator of transcription 5A — part of (P361): SH2 domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[10] ↑ Signal transducer and activator of transcription 5A — part of (P361): STAT transcription factor, N-terminal domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[11] ↑ Signal transducer and activator of transcription 5A — part of (P361): STAT transcription factor, protein interaction, protein family. wikidata.org.
[12] ↑ Signal transducer and activator of transcription 5A — part of (P361): SH2 domain, protein family. wikidata.org.
[13] ↑ Signal transducer and activator of transcription 5A — part of (P361): STAT transcription factor, DNA-binding domain, protein family. wikidata.org.
[14] ↑ Signal transducer and activator of transcription 5A — part of (P361): STAT transcription factor, all-alpha domain, protein family. wikidata.org.
[15] ↑ Signal transducer and activator of transcription 5A — has part(s) (P527): STAT transcription factor, DNA-binding. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ Signal transducer and activator of transcription 5A — has part(s) (P527): SH2 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Signal transducer and activator of transcription 5A — has part(s) (P527): STAT transcription factor, all-alpha domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Signal transducer and activator of transcription 5A — has part(s) (P527): STAT transcription factor, protein interaction. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ Signal transducer and activator of transcription 5A — RefSeq protein ID (P637): NP_001157534. Q20641742. Retrieved 2022-03-20. wikidata.org.
[20] ↑ Signal transducer and activator of transcription 5A — RefSeq protein ID (P637): NP_035618. Q20641742. Retrieved 2022-03-20. wikidata.org.
[21] ↑ Signal transducer and activator of transcription 5A — RefSeq protein ID (P637): XP_006532784. Q20641742. Retrieved 2022-03-20. wikidata.org.
[22] ↑ Signal transducer and activator of transcription 5A — RefSeq protein ID (P637): XP_017169891. Q20641742. Retrieved 2022-03-20. wikidata.org.
[23] ↑ Signal transducer and activator of transcription 5A — RefSeq protein ID (P637): NP_001349609. Q20641742. Retrieved 2022-03-20. wikidata.org.
[24] ↑ Signal transducer and activator of transcription 5A — PDB structure ID (P638): 1Y1U. Q905695. Retrieved 2016-08-09. wikidata.org.
[25] ↑ Signal transducer and activator of transcription 5A — molecular function (P680): DNA binding. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ Signal transducer and activator of transcription 5A — molecular function (P680): protein binding. CPAP is a novel stat5-interacting cofactor that augments stat5-mediated transcriptional activity. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Signal transducer and activator of transcription 5A is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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APA

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MLA

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BibTeX

@misc{4ortxyz_signal-transducer-and-activator-of-transcription-5a_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Signal transducer and activator of transcription 5A}}, year = {2026}, url = {https://4ort.xyz/entity/signal-transducer-and-activator-of-transcription-5a}, note = {Accessed: 2026-05-03}}

LLM prompt

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