Signal transducer and activator of transcription 4

mammalian protein found in Homo sapiens

Protein protein Q3943950

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Signal transducer and activator of transcription 4

Summary

Signal transducer and activator of transcription 4 is a protein^[1].

Key Facts

Signal transducer and activator of transcription 4's instance of is recorded as protein^[2].
Signal transducer and activator of transcription 4's UniProt protein ID is recorded as Cea River^[3].
Signal transducer and activator of transcription 4's part of is recorded as p53-like transcription factor, DNA-binding^[4].
Signal transducer and activator of transcription 4's part of is recorded as STAT transcription factor, DNA-binding, N-terminal^[5].
Signal transducer and activator of transcription 4's part of is recorded as Signal transducer and activator of transcription 4^[6].
Signal transducer and activator of transcription 4's part of is recorded as STAT transcription factor, coiled coil^[7].
Signal transducer and activator of transcription 4's part of is recorded as SH2 domain superfamily^[8].
Signal transducer and activator of transcription 4's part of is recorded as STAT transcription factor, N-terminal domain superfamily^[9].
Signal transducer and activator of transcription 4's part of is recorded as STAT transcription factor, protein interaction, protein family^[10].
Signal transducer and activator of transcription 4's part of is recorded as SH2 domain, protein family^[11].
Signal transducer and activator of transcription 4's part of is recorded as STAT transcription factor, DNA-binding domain, protein family^[12].
Signal transducer and activator of transcription 4's part of is recorded as STAT transcription factor, all-alpha domain, protein family^[13].
Signal transducer and activator of transcription 4's part of is recorded as STAT4, SH2 domain, protein family^[14].
Signal transducer and activator of transcription 4's MeSH descriptor ID is recorded as D050797^[15].
Signal transducer and activator of transcription 4's has part is recorded as SH2 domain^[16].
Signal transducer and activator of transcription 4's has part is recorded as STAT transcription factor, all-alpha domain^[17].
Signal transducer and activator of transcription 4's has part is recorded as STAT transcription factor, DNA-binding^[18].
Signal transducer and activator of transcription 4's has part is recorded as STAT transcription factor, protein interaction^[19].
Signal transducer and activator of transcription 4's has part is recorded as STAT4, SH2 domain^[20].
Signal transducer and activator of transcription 4's RefSeq protein ID is recorded as NP_001230764^[21].
Signal transducer and activator of transcription 4's RefSeq protein ID is recorded as NP_003142^[22].
Signal transducer and activator of transcription 4's RefSeq protein ID is recorded as XP_006712782^[23].
Signal transducer and activator of transcription 4's RefSeq protein ID is recorded as XP_011510007^[24].
Signal transducer and activator of transcription 4's RefSeq protein ID is recorded as XP_016860273^[25].
Signal transducer and activator of transcription 4's Freebase ID is recorded as /m/02rypxb^[26].

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Quick Facts

Instance of protein

Part of p53-like transcription factor, DNA-binding, STAT transcription factor, DNA-binding, N-terminal, Signal transducer and activator of transcription 4, STAT transcription factor, coiled coil, SH2 domain superfamily, STAT transcription factor, N-terminal domain superfamily, STAT transcription factor, protein interaction, protein family, SH2 domain, protein family, STAT transcription factor, DNA-binding domain, protein family, STAT transcription factor, all-alpha domain, protein family, STAT4, SH2 domain, protein family

Properties

Biological process transcription, DNA-templated, regulation of transcription, DNA-templated, receptor signaling pathway via JAK-STAT, signal transduction, positive regulation of transcription by RNA polymerase II, interleukin-12-mediated signaling pathway, cytokine-mediated signaling pathway, interleukin-21-mediated signaling pathway, interleukin-23-mediated signaling pathway, interleukin-35-mediated signaling pathway, defense response, receptor signaling pathway via JAK-STAT, cytokine-mediated signaling pathway, regulation of cell population proliferation, response to peptide hormone, positive regulation of transcription by RNA polymerase II

Cell component cytoplasm, nucleus, nucleoplasm, cytosol, nucleus, cytosol

Encoded by STAT4

Found in taxon Homo sapiens

Has part(s) SH2 domain, STAT transcription factor, all-alpha domain, STAT transcription factor, DNA-binding, STAT transcription factor, protein interaction, STAT4, SH2 domain

Imported from wholeness_audit_2026-05-02

Molecular function protein binding, DNA-binding transcription factor activity, DNA binding, identical protein binding, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific

External References (7)

Ensembl protein id ENSP00000351255, ENSP00000376134, ENSP00000386288, ENSP00000403238, ENSP00000412397, ENSP00000414322, ENSP00000495153

Freebase id /m/02rypxb

Mesh descriptor id D050797

Mesh tree code D12.644.360.024.342.400, D12.776.157.057.186.400, D12.776.476.024.430.400, D12.776.930.840.400

Refseq protein id NP_001230764, NP_003142, XP_006712782, XP_011510007, XP_016860273

Umls cui C0255034

Uniprot protein id Cea River

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Signal transducer and activator of transcription 4 — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ Signal transducer and activator of transcription 4 — UniProt protein ID (P352): Cea River. Q905695. Retrieved 2019-11-13. wikidata.org.
[4] ↑ Signal transducer and activator of transcription 4 — part of (P361): p53-like transcription factor, DNA-binding. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ Signal transducer and activator of transcription 4 — part of (P361): STAT transcription factor, DNA-binding, N-terminal. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Signal transducer and activator of transcription 4 — part of (P361): Signal transducer and activator of transcription 4. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Signal transducer and activator of transcription 4 — part of (P361): STAT transcription factor, coiled coil. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Signal transducer and activator of transcription 4 — part of (P361): SH2 domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[9] ↑ Signal transducer and activator of transcription 4 — part of (P361): STAT transcription factor, N-terminal domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[10] ↑ Signal transducer and activator of transcription 4 — part of (P361): STAT transcription factor, protein interaction, protein family. wikidata.org.
[11] ↑ Signal transducer and activator of transcription 4 — part of (P361): SH2 domain, protein family. wikidata.org.
[12] ↑ Signal transducer and activator of transcription 4 — part of (P361): STAT transcription factor, DNA-binding domain, protein family. wikidata.org.
[13] ↑ Signal transducer and activator of transcription 4 — part of (P361): STAT transcription factor, all-alpha domain, protein family. wikidata.org.
[14] ↑ Signal transducer and activator of transcription 4 — part of (P361): STAT4, SH2 domain, protein family. wikidata.org.
[15] ↑ Signal transducer and activator of transcription 4 — MeSH descriptor ID (P486): D050797. wikidata.org.
[16] ↑ Signal transducer and activator of transcription 4 — has part(s) (P527): SH2 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Signal transducer and activator of transcription 4 — has part(s) (P527): STAT transcription factor, all-alpha domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Signal transducer and activator of transcription 4 — has part(s) (P527): STAT transcription factor, DNA-binding. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ Signal transducer and activator of transcription 4 — has part(s) (P527): STAT transcription factor, protein interaction. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ Signal transducer and activator of transcription 4 — has part(s) (P527): STAT4, SH2 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ Signal transducer and activator of transcription 4 — RefSeq protein ID (P637): NP_001230764. Q20641742. Retrieved 2020-05-30. wikidata.org.
[22] ↑ Signal transducer and activator of transcription 4 — RefSeq protein ID (P637): NP_003142. Q20641742. Retrieved 2020-05-30. wikidata.org.
[23] ↑ Signal transducer and activator of transcription 4 — RefSeq protein ID (P637): XP_006712782. Q20641742. Retrieved 2020-05-30. wikidata.org.
[24] ↑ Signal transducer and activator of transcription 4 — RefSeq protein ID (P637): XP_011510007. Q20641742. Retrieved 2020-05-30. wikidata.org.
[25] ↑ Signal transducer and activator of transcription 4 — RefSeq protein ID (P637): XP_016860273. Q20641742. Retrieved 2020-05-30. wikidata.org.
[26] ↑ Signal transducer and activator of transcription 4 — Freebase ID (P646): /m/02rypxb. Freebase Data Dumps. wikidata.org.

Class ancestry

[1] ↑ Signal transducer and activator of transcription 4 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). Signal transducer and activator of transcription 4. Retrieved May 3, 2026, from https://4ort.xyz/entity/signal-transducer-and-activator-of-transcription-4-q3943950

MLA

“Signal transducer and activator of transcription 4.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/signal-transducer-and-activator-of-transcription-4-q3943950.

BibTeX

@misc{4ortxyz_signal-transducer-and-activator-of-transcription-4-q3943950_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Signal transducer and activator of transcription 4}}, year = {2026}, url = {https://4ort.xyz/entity/signal-transducer-and-activator-of-transcription-4-q3943950}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Signal transducer and activator of transcription 4 — https://4ort.xyz/entity/signal-transducer-and-activator-of-transcription-4-q3943950 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/signal-transducer-and-activator-of-transcription-4-q3943950 · Last refreshed: May 3, 2026