Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D

mammalian protein found in Mus musculus

Protein protein Q21991435

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Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D

Summary

Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D is a protein^[1].

Key Facts

Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D's instance of is recorded as protein^[2].
Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D's UniProt protein ID is recorded as O09126^[3].
Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D's part of is recorded as Sema domain superfamily^[4].
Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D's part of is recorded as Immunoglobulin-like fold^[5].
Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D's part of is recorded as semaphorin^[6].
Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D's part of is recorded as Immunoglobulin-like domain superfamily^[7].
Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D's part of is recorded as WD40/YVTN repeat-like-containing domain superfamily^[8].
Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D's part of is recorded as membrane protein^[9].
Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D's part of is recorded as Sema domain, protein family^[10].
Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D's part of is recorded as PSI domain, protein family^[11].
Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D's part of is recorded as Immunoglobulin subtype 2, protein family^[12].
Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D's part of is recorded as immunoglobulin-like domain, protein family^[13].
Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D's part of is recorded as Plexin repeat, protein family^[14].
Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D's part of is recorded as Immunoglobulin domain, protein family^[15].
Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D's has part is recorded as immunoglobulin domain^[16].
Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D's has part is recorded as Sema domain^[17].
Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D's has part is recorded as immunoglobulin subtype 2^[18].
Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D's has part is recorded as Plexin repeat^[19].
Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D's has part is recorded as immunoglobulin-like domain^[20].
Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D's has part is recorded as PSI domain^[21].
Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D's RefSeq protein ID is recorded as NP_001268809^[22].
Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D's RefSeq protein ID is recorded as NP_038688^[23].
Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D's RefSeq protein ID is recorded as NP_001365242^[24].
Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D's RefSeq protein ID is recorded as NP_001365243^[25].
Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D's RefSeq protein ID is recorded as NP_001365246^[26].

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Quick Facts

Instance of protein

Part of Sema domain superfamily, Immunoglobulin-like fold, semaphorin, Immunoglobulin-like domain superfamily, WD40/YVTN repeat-like-containing domain superfamily, membrane protein, Sema domain, protein family, PSI domain, protein family, Immunoglobulin subtype 2, protein family, immunoglobulin-like domain, protein family, Plexin repeat, protein family, Immunoglobulin domain, protein family

Properties

Biological process semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis, nervous system development, multicellular organism development, cell differentiation, negative regulation of osteoblast differentiation, negative regulation of peptidyl-tyrosine phosphorylation, positive regulation of peptidyl-tyrosine phosphorylation, ossification involved in bone maturation, negative regulation of cell adhesion, positive regulation of protein phosphorylation, positive regulation of cell migration, negative regulation of transcription by RNA polymerase II, positive regulation of collateral sprouting, positive regulation of axonogenesis, leukocyte aggregation, regulation of dendrite morphogenesis, positive regulation of GTPase activity, regulation of cell shape, negative regulation of alkaline phosphatase activity, positive regulation of phosphatidylinositol 3-kinase signaling, semaphorin-plexin signaling pathway, regulation of cell projection organization, negative chemotaxis, neural crest cell migration, positive regulation of cell migration, negative regulation of axon extension involved in axon guidance, semaphorin-plexin signaling pathway

Cell component integral component of membrane, membrane, integral component of plasma membrane, extracellular space, plasma membrane, extracellular space, plasma membrane, integral component of plasma membrane

Encoded by Sema4d

Found in taxon house mouse

Has part(s) immunoglobulin domain, Sema domain, immunoglobulin subtype 2, Plexin repeat, immunoglobulin-like domain, PSI domain

Imported from wholeness_audit_2026-05-02

Molecular function semaphorin receptor binding, signaling receptor binding, transmembrane signaling receptor activity, protein binding, neuropilin binding, identical protein binding, signaling receptor activity, semaphorin receptor binding, chemorepellent activity

External References (3)

Ensembl protein id ENSMUSP00000021900, ENSMUSP00000105666, ENSMUSP00000105667, ENSMUSP00000105669

Refseq protein id NP_001268809, NP_038688, NP_001365242, NP_001365243, NP_001365246, NP_001365247, NP_001365248, NP_001365249, NP_001365251, NP_001365252, NP_001365253, NP_001365244, NP_001365245, NP_001365250, NP_001365254, XP_036013838, XP_036013839, XP_036013840, XP_036013841

Uniprot protein id O09126

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D — instance of (P31): protein. Q905695. Retrieved 2022-05-25. wikidata.org.
[3] ↑ Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D — UniProt protein ID (P352): O09126. Q905695. Retrieved 2022-05-25. wikidata.org.
[4] ↑ Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D — part of (P361): Sema domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D — part of (P361): Immunoglobulin-like fold. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D — part of (P361): semaphorin. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D — part of (P361): Immunoglobulin-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D — part of (P361): WD40/YVTN repeat-like-containing domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[9] ↑ Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D — part of (P361): membrane protein. wikidata.org.
[10] ↑ Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D — part of (P361): Sema domain, protein family. wikidata.org.
[11] ↑ Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D — part of (P361): PSI domain, protein family. wikidata.org.
[12] ↑ Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D — part of (P361): Immunoglobulin subtype 2, protein family. wikidata.org.
[13] ↑ Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D — part of (P361): immunoglobulin-like domain, protein family. wikidata.org.
[14] ↑ Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D — part of (P361): Plexin repeat, protein family. wikidata.org.
[15] ↑ Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D — part of (P361): Immunoglobulin domain, protein family. wikidata.org.
[16] ↑ Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D — has part(s) (P527): immunoglobulin domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D — has part(s) (P527): Sema domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D — has part(s) (P527): immunoglobulin subtype 2. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D — has part(s) (P527): Plexin repeat. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D — has part(s) (P527): immunoglobulin-like domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D — has part(s) (P527): PSI domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D — RefSeq protein ID (P637): NP_001268809. Q20641742. Retrieved 2022-03-20. wikidata.org.
[23] ↑ Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D — RefSeq protein ID (P637): NP_038688. Q20641742. Retrieved 2022-03-20. wikidata.org.
[24] ↑ Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D — RefSeq protein ID (P637): NP_001365242. Q20641742. Retrieved 2022-03-20. wikidata.org.
[25] ↑ Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D — RefSeq protein ID (P637): NP_001365243. Q20641742. Retrieved 2022-03-20. wikidata.org.
[26] ↑ Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D — RefSeq protein ID (P637): NP_001365246. Q20641742. Retrieved 2022-03-20. wikidata.org.

Class ancestry

[1] ↑ Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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APA

4ort.xyz Knowledge Graph. (2026). Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D. Retrieved May 3, 2026, from https://4ort.xyz/entity/sema-domain-immunoglobulin-domain-ig-transmembrane-domain-tm-and-short-cytoplasmic-domain-semaphorin-4d

MLA

“Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/sema-domain-immunoglobulin-domain-ig-transmembrane-domain-tm-and-short-cytoplasmic-domain-semaphorin-4d.

BibTeX

@misc{4ortxyz_sema-domain-immunoglobulin-domain-ig-transmembrane-domain-tm-and-short-cytoplasmic-domain-semaphorin-4d_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D}}, year = {2026}, url = {https://4ort.xyz/entity/sema-domain-immunoglobulin-domain-ig-transmembrane-domain-tm-and-short-cytoplasmic-domain-semaphorin-4d}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D — https://4ort.xyz/entity/sema-domain-immunoglobulin-domain-ig-transmembrane-domain-tm-and-short-cytoplasmic-domain-semaphorin-4d (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/sema-domain-immunoglobulin-domain-ig-transmembrane-domain-tm-and-short-cytoplasmic-domain-semaphorin-4d · Last refreshed: May 3, 2026