Phospholipase C beta 1
mammalian protein found in Homo sapiens
Summary
Phospholipase C beta 1 is a protein[1]
Key Facts
Phospholipase C beta 1's instance of is recorded as protein[2]
Phospholipase C beta 1 is part of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1[3]
Phospholipase C beta 1 is part of EF-hand domain pair[4]
Phospholipase C beta 1 is part of C2 domain superfamily[5]
Phospholipase C beta 1 is part of PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily[6]
Phospholipase C beta 1 is part of PLC-beta, PH domain, protein family[7]
Phospholipase C beta 1 is part of C2 domain, protein family[8]
Phospholipase C beta 1 is part of Phosphatidylinositol-specific phospholipase C, X domain, protein family[9]
Phospholipase C beta 1 is part of Phospholipase C-beta, C-terminal domain, protein family[10]
Phospholipase C beta 1 is part of Phospholipase C, phosphatidylinositol-specific, Y domain, protein family[11]
Phospholipase C beta 1 is part of Phosphoinositide-specific phospholipase C, EF-hand-like domain, protein family[12]
Phospholipase C beta 1 is part of Phospholipase C-beta, conserved site, protein family[13]
Phospholipase C beta 1 comprises Phospholipase C-beta, C-terminal domain[14]
Phospholipase C beta 1 comprises Phosphoinositide-specific phospholipase C, EF-hand-like domain[15]
Phospholipase C beta 1 comprises Phosphatidylinositol-specific phospholipase C, X domain[16]
Phospholipase C beta 1 comprises Phospholipase C, phosphatidylinositol-specific, Y domain[17]
Phospholipase C beta 1 comprises C2 domain[18]
Phospholipase C beta 1 comprises Phospholipase C-beta, conserved site[19]
Phospholipase C beta 1 comprises PLC-beta, PH domain[20]
Phospholipase C beta 1's molecular function is recorded as calcium ion binding[21]
Phospholipase C beta 1's molecular function is recorded as protein homodimerization activity[22]
Phospholipase C beta 1's molecular function is recorded as GTPase activator activity[23]
Phospholipase C beta 1's molecular function is recorded as signal transducer activity[24]
Phospholipase C beta 1's molecular function is recorded as protein binding[25]
Phospholipase C beta 1's molecular function is recorded as phosphoric diester hydrolase activity[26]
⭐ Popularity Graph
0/100
established
Quick Facts
Part of
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1, EF-hand domain pair, C2 domain superfamily, PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily, PLC-beta, PH domain, protein family, C2 domain, protein family, Phosphatidylinositol-specific phospholipase C, X domain, protein family, Phospholipase C-beta, C-terminal domain, protein family, Phospholipase C, phosphatidylinositol-specific, Y domain, protein family, Phosphoinositide-specific phospholipase C, EF-hand-like domain, protein family, Phospholipase C-beta, conserved site, protein family
Properties
Biological process
G protein-coupled acetylcholine receptor signaling pathway, glutamate receptor signaling pathway, insulin-like growth factor receptor signaling pathway, interleukin-15-mediated signaling pathway, intracellular signal transduction, positive regulation of developmental growth, phosphatidylinositol metabolic process, negative regulation of monocyte extravasation, positive regulation of interleukin-12 production, regulation of G protein-coupled receptor signaling pathway, lipid metabolism , inositol phosphate metabolic process, positive regulation of JNK cascade, memory , regulation of cell cycle , positive regulation of transcription, DNA-templated, lipid catabolic process, positive regulation of G1/S transition of mitotic cell cycle, interleukin-1-mediated signaling pathway, positive regulation of acrosome reaction, brain development, G2/M transition of mitotic cell cycle, interleukin-12-mediated signaling pathway, positive regulation of myoblast differentiation, positive regulation of CD24 production, cerebral cortex development, activation of meiosis involved in egg activation, regulation of fertilization, positive regulation of embryonic development, negative regulation of transcription, DNA-templated, fat cell differentiation, signal transduction , Wnt signaling pathway, calcium modulating pathway, positive regulation of GTPase activity, G protein-coupled receptor signaling pathway, memory , postsynaptic modulation of chemical synaptic transmission, regulation of retrograde trans-synaptic signaling by endocanabinoid, inositol trisphosphate biosynthetic process, phosphatidylinositol-mediated signaling, release of sequestered calcium ion into cytosol
Cell component
cytoplasm , cytosol , nuclear speck , nuclear membrane , membrane , myelin sheath , extracellular exosome , nucleus , nucleus , cytoplasm , nuclear speck , extracellular exosome , postsynapse, glutamatergic synapse, GABA-ergic synapse, protein-containing complex
Ec enzyme number
3.1.4.11
Has part(s)
Phospholipase C-beta, C-terminal domain, Phosphoinositide-specific phospholipase C, EF-hand-like domain, Phosphatidylinositol-specific phospholipase C, X domain, Phospholipase C, phosphatidylinositol-specific, Y domain, C2 domain, Phospholipase C-beta, conserved site, PLC-beta, PH domain
Molecular function
calcium ion binding, protein homodimerization activity, GTPase activator activity, signal transducer activity, protein binding , phosphoric diester hydrolase activity, enzyme binding, phosphatidylinositol-4,5-bisphosphate binding, hydrolase activity, lamin binding, phosphatidylinositol phospholipase C activity, phospholipase C activity, calmodulin binding, phosphatidylinositol phospholipase C activity, protein binding , calmodulin binding, phosphatidylinositol phospholipase C activity
External References (3)
Ensembl protein id
ENSP00000338185, ENSP00000367904, ENSP00000367908, ENSP00000384001, ENSP00000389911, ENSP00000391162, ENSP00000431704, ENSP00000477664, ENSP00000479997, ENSP00000486301, ENSP00000486428, ENSP00000486531, ENSP00000486655, ENSP00000487075, ENSP00000487544, ENSP00000489643, ENSP00000490455, ENSP00000490641, ENSP00000490771, ENSP00000490792, ENSP00000490862
Refseq protein id
NP_056007, NP_877398
Uniprot protein id
Q9NQ66
🏷️ Also known as
en 1-phosphatidyl-D-myo-inositol-4,5-bisphosphateen 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1en inositoltrisphosphohydrolaseen monophosphatidylinositol phosphodiesteraseen phosphoinositidase Cen phosphoinositide phospholipase Cen Phosphoinositide phospholipase C-beta-1en Phospholipase C beta 1en Phospholipase C-beta-1en phospholipase C, beta 1 (phosphoinositide-specific)en phospholipase C-Ien PLC-154en PLCB1en PLC-beta-1en PLC-Ien triphosphoinositide phosphodiesterase
