Nuclear receptor subfamily 1, group H, member 4

mammalian protein found in Mus musculus

Protein protein Q14905046

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Nuclear receptor subfamily 1, group H, member 4

Summary

Nuclear receptor subfamily 1, group H, member 4 is a protein^[1].

Key Facts

Nuclear receptor subfamily 1, group H, member 4's instance of is recorded as protein^[2].
Nuclear receptor subfamily 1, group H, member 4's subclass of is recorded as protein^[3].
Nuclear receptor subfamily 1, group H, member 4's UniProt protein ID is recorded as Madhukar^[4].
Nuclear receptor subfamily 1, group H, member 4's part of is recorded as Nuclear hormone receptor-like domain superfamily^[5].
Nuclear receptor subfamily 1, group H, member 4's part of is recorded as Zinc finger, NHR/GATA-type^[6].
Nuclear receptor subfamily 1, group H, member 4's part of is recorded as thyroid hormone receptor^[7].
Nuclear receptor subfamily 1, group H, member 4's part of is recorded as Nuclear hormone receptor, ligand-binding domain, protein family^[8].
Nuclear receptor subfamily 1, group H, member 4's part of is recorded as Zinc finger, nuclear hormone receptor-type, protein family^[9].
Nuclear receptor subfamily 1, group H, member 4's has part is recorded as Nuclear hormone receptor, ligand-binding domain^[10].
Nuclear receptor subfamily 1, group H, member 4's has part is recorded as nuclear hormone receptor-type zinc finger^[11].
Nuclear receptor subfamily 1, group H, member 4's RefSeq protein ID is recorded as NP_001156976^[12].
Nuclear receptor subfamily 1, group H, member 4's RefSeq protein ID is recorded as NP_001157172^[13].
Nuclear receptor subfamily 1, group H, member 4's RefSeq protein ID is recorded as NP_033134^[14].
Nuclear receptor subfamily 1, group H, member 4's RefSeq protein ID is recorded as XP_006513454^[15].
Nuclear receptor subfamily 1, group H, member 4's RefSeq protein ID is recorded as XP_030100823^[16].
Nuclear receptor subfamily 1, group H, member 4's RefSeq protein ID is recorded as NP_001372640^[17].
Nuclear receptor subfamily 1, group H, member 4's molecular function is recorded as RNA polymerase II cis-regulatory region sequence-specific DNA binding^[18].
Nuclear receptor subfamily 1, group H, member 4's molecular function is recorded as sequence-specific DNA binding^[19].
Nuclear receptor subfamily 1, group H, member 4's molecular function is recorded as DNA-binding transcription factor activity^[20].
Nuclear receptor subfamily 1, group H, member 4's molecular function is recorded as zinc ion binding^[21].
Nuclear receptor subfamily 1, group H, member 4's molecular function is recorded as DNA-binding transcription activator activity, RNA polymerase II-specific^[22].
Nuclear receptor subfamily 1, group H, member 4's molecular function is recorded as bile acid receptor activity^[23].
Nuclear receptor subfamily 1, group H, member 4's molecular function is recorded as metal ion binding^[24].
Nuclear receptor subfamily 1, group H, member 4's molecular function is recorded as retinoid X receptor binding^[25].
Nuclear receptor subfamily 1, group H, member 4's molecular function is recorded as transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding^[26].

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Quick Facts

Instance of protein

Subclass of protein

Part of Nuclear hormone receptor-like domain superfamily, Zinc finger, NHR/GATA-type, thyroid hormone receptor, Nuclear hormone receptor, ligand-binding domain, protein family, Zinc finger, nuclear hormone receptor-type, protein family

Properties

Biological process Notch signaling pathway, cellular response to organonitrogen compound, negative regulation of monocyte chemotactic protein-1 production, negative regulation of interferon-gamma production, positive regulation of adipose tissue development, positive regulation of ammonia assimilation cycle, glucose homeostasis, negative regulation of tumor necrosis factor-mediated signaling pathway, immune system process, regulation of transcription by RNA polymerase II, negative regulation of interleukin-1 production, negative regulation of interleukin-6 production, positive regulation of glutamate metabolic process, intracellular bile acid receptor signaling pathway, transcription, DNA-templated, regulation of urea metabolic process, intracellular receptor signaling pathway, negative regulation of bile acid biosynthetic process, fatty acid homeostasis, defense response to bacterium, cell-cell junction assembly, nitrogen catabolite activation of transcription from RNA polymerase II promoter, positive regulation of insulin secretion involved in cellular response to glucose stimulus, negative regulation of tumor necrosis factor production, toll-like receptor 9 signaling pathway, positive regulation of insulin receptor signaling pathway, inflammatory response, cellular response to lipopolysaccharide, negative regulation of NF-kappaB transcription factor activity, innate immune response, negative regulation of interleukin-2 production, negative regulation of inflammatory response, triglyceride homeostasis, positive regulation of transcription by RNA polymerase II, steroid hormone mediated signaling pathway, negative regulation of I-kappaB kinase/NF-kappaB signaling, regulation of insulin secretion involved in cellular response to glucose stimulus, toll-like receptor 4 signaling pathway, bile acid signaling pathway, cellular triglyceride homeostasis, regulation of low-density lipoprotein particle clearance, histone H3-R17 methylation, negative regulation of apoptotic process, transcription by RNA polymerase II, cellular response to fatty acid, regulation of transcription, DNA-templated, positive regulation of phosphatidic acid biosynthetic process, cholesterol homeostasis, negative regulation of transcription by RNA polymerase II, regulation of carbohydrate metabolic process, bile acid metabolic process, negative regulation of transcription by RNA polymerase II, lipid metabolism, multicellular organism development, cell differentiation, bile acid signaling pathway, cholesterol homeostasis, positive regulation of transcription by RNA polymerase II, negative regulation of inflammatory response, lipid homeostasis, cellular response to lipopolysaccharide, cellular glucose homeostasis

Cell component nucleus, nucleus, RNA polymerase II transcription regulator complex

Encoded by Nr1h4

Found in taxon house mouse

Has part(s) Nuclear hormone receptor, ligand-binding domain, nuclear hormone receptor-type zinc finger

Imported from wholeness_audit_2026-05-02

Molecular function RNA polymerase II cis-regulatory region sequence-specific DNA binding, sequence-specific DNA binding, DNA-binding transcription factor activity, zinc ion binding, DNA-binding transcription activator activity, RNA polymerase II-specific, bile acid receptor activity, metal ion binding, retinoid X receptor binding, transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding, chenodeoxycholic acid binding, steroid hormone receptor activity, transcription cis-regulatory region binding, RNA polymerase II transcription regulatory region sequence-specific DNA binding, nuclear receptor activity, protein binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA binding, double-stranded DNA binding, bile acid binding, peptide binding, protein heterodimerization activity, transcription cis-regulatory region binding, RNA polymerase II transcription regulatory region sequence-specific DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA-binding transcription activator activity, RNA polymerase II-specific, transcription factor binding, nuclear receptor coactivator activity, bile acid binding, signaling receptor activity, bile acid receptor activity, DNA-binding transcription factor activity, RNA polymerase II-specific

External References (3)

Ensembl protein id ENSMUSP00000100933, ENSMUSP00000053092, ENSMUSP00000100934

Refseq protein id NP_001156976, NP_001157172, NP_033134, XP_006513454, XP_030100823, NP_001372640

Uniprot protein id Madhukar

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Nuclear receptor subfamily 1, group H, member 4 — instance of (P31): protein. Q905695. Retrieved 2022-05-25. wikidata.org.
[3] ↑ Nuclear receptor subfamily 1, group H, member 4 — subclass of (P279): protein. Q905695. Retrieved 2017-01-19. wikidata.org.
[4] ↑ Nuclear receptor subfamily 1, group H, member 4 — UniProt protein ID (P352): Madhukar. Q905695. Retrieved 2022-05-25. wikidata.org.
[5] ↑ Nuclear receptor subfamily 1, group H, member 4 — part of (P361): Nuclear hormone receptor-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Nuclear receptor subfamily 1, group H, member 4 — part of (P361): Zinc finger, NHR/GATA-type. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Nuclear receptor subfamily 1, group H, member 4 — part of (P361): thyroid hormone receptor. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Nuclear receptor subfamily 1, group H, member 4 — part of (P361): Nuclear hormone receptor, ligand-binding domain, protein family. wikidata.org.
[9] ↑ Nuclear receptor subfamily 1, group H, member 4 — part of (P361): Zinc finger, nuclear hormone receptor-type, protein family. wikidata.org.
[10] ↑ Nuclear receptor subfamily 1, group H, member 4 — has part(s) (P527): Nuclear hormone receptor, ligand-binding domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[11] ↑ Nuclear receptor subfamily 1, group H, member 4 — has part(s) (P527): nuclear hormone receptor-type zinc finger. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[12] ↑ Nuclear receptor subfamily 1, group H, member 4 — RefSeq protein ID (P637): NP_001156976. Q20641742. Retrieved 2022-03-20. wikidata.org.
[13] ↑ Nuclear receptor subfamily 1, group H, member 4 — RefSeq protein ID (P637): NP_001157172. Q20641742. Retrieved 2022-03-20. wikidata.org.
[14] ↑ Nuclear receptor subfamily 1, group H, member 4 — RefSeq protein ID (P637): NP_033134. Q20641742. Retrieved 2022-03-20. wikidata.org.
[15] ↑ Nuclear receptor subfamily 1, group H, member 4 — RefSeq protein ID (P637): XP_006513454. Q20641742. Retrieved 2022-03-20. wikidata.org.
[16] ↑ Nuclear receptor subfamily 1, group H, member 4 — RefSeq protein ID (P637): XP_030100823. Q20641742. Retrieved 2022-03-20. wikidata.org.
[17] ↑ Nuclear receptor subfamily 1, group H, member 4 — RefSeq protein ID (P637): NP_001372640. Q20641742. Retrieved 2022-03-20. wikidata.org.
[18] ↑ Nuclear receptor subfamily 1, group H, member 4 — molecular function (P680): RNA polymerase II cis-regulatory region sequence-specific DNA binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ Nuclear receptor subfamily 1, group H, member 4 — molecular function (P680): sequence-specific DNA binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ Nuclear receptor subfamily 1, group H, member 4 — molecular function (P680): DNA-binding transcription factor activity. Isolation of proteins that interact specifically with the retinoid X receptor: two novel orphan receptors. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ Nuclear receptor subfamily 1, group H, member 4 — molecular function (P680): zinc ion binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ Nuclear receptor subfamily 1, group H, member 4 — molecular function (P680): DNA-binding transcription activator activity, RNA polymerase II-specific. GOA. Retrieved 2018-10-11. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ Nuclear receptor subfamily 1, group H, member 4 — molecular function (P680): bile acid receptor activity. GOA. Retrieved 2018-04-24. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ Nuclear receptor subfamily 1, group H, member 4 — molecular function (P680): metal ion binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ Nuclear receptor subfamily 1, group H, member 4 — molecular function (P680): retinoid X receptor binding. Isolation of proteins that interact specifically with the retinoid X receptor: two novel orphan receptors. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ Nuclear receptor subfamily 1, group H, member 4 — molecular function (P680): transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding. GOA. Retrieved 2018-10-11. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Nuclear receptor subfamily 1, group H, member 4 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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APA

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MLA

“Nuclear receptor subfamily 1, group H, member 4.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/nuclear-receptor-subfamily-1-group-h-member-4-q14905046.

BibTeX

@misc{4ortxyz_nuclear-receptor-subfamily-1-group-h-member-4-q14905046_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Nuclear receptor subfamily 1, group H, member 4}}, year = {2026}, url = {https://4ort.xyz/entity/nuclear-receptor-subfamily-1-group-h-member-4-q14905046}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Nuclear receptor subfamily 1, group H, member 4 — https://4ort.xyz/entity/nuclear-receptor-subfamily-1-group-h-member-4-q14905046 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/nuclear-receptor-subfamily-1-group-h-member-4-q14905046 · Last refreshed: May 3, 2026