NPC intracellular cholesterol transporter 1

mammalian protein found in Homo sapiens
Protein protein Q6748237
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NPC intracellular cholesterol transporter 1

Summary

NPC intracellular cholesterol transporter 1 is a protein[1].

Key Facts

  • NPC intracellular cholesterol transporter 1's instance of is recorded as protein[2].
  • NPC intracellular cholesterol transporter 1 is part of NPC intracellular cholesterol transporter 1[3].
  • NPC intracellular cholesterol transporter 1 is part of NPC1:NPC2[4].
  • NPC intracellular cholesterol transporter 1 is part of Niemann-Pick C1, N-terminal domain, protein family[5].
  • NPC intracellular cholesterol transporter 1 is part of Sterol-sensing domain, protein family[6].
  • NPC intracellular cholesterol transporter 1's Commons category is recorded as NPC1[7].
  • NPC intracellular cholesterol transporter 1 comprises Sterol-sensing domain[8].
  • NPC intracellular cholesterol transporter 1 comprises Niemann-Pick C1, N-terminal[9].
  • NPC intracellular cholesterol transporter 1's molecular function is recorded as virus receptor activity[10].
  • NPC intracellular cholesterol transporter 1's molecular function is recorded as lipid transporter activity[11].
  • NPC intracellular cholesterol transporter 1's molecular function is recorded as sterol transporter activity[12].
  • NPC intracellular cholesterol transporter 1's molecular function is recorded as cholesterol binding[13].
  • NPC intracellular cholesterol transporter 1's molecular function is recorded as protein binding[14].
  • NPC intracellular cholesterol transporter 1's molecular function is recorded as transmembrane signaling receptor activity[15].
  • NPC intracellular cholesterol transporter 1's molecular function is recorded as signaling receptor activity[16].
  • NPC intracellular cholesterol transporter 1's cell component is recorded as integral component of membrane[17].
  • NPC intracellular cholesterol transporter 1's cell component is recorded as vesicle[18].
  • NPC intracellular cholesterol transporter 1's cell component is recorded as endosome[19].
  • NPC intracellular cholesterol transporter 1's cell component is recorded as Golgi apparatus[20].
  • NPC intracellular cholesterol transporter 1's cell component is recorded as nuclear envelope[21].
  • NPC intracellular cholesterol transporter 1's cell component is recorded as membrane[22].
  • NPC intracellular cholesterol transporter 1's cell component is recorded as late endosome membrane[23].
  • NPC intracellular cholesterol transporter 1's cell component is recorded as plasma membrane[24].
  • NPC intracellular cholesterol transporter 1's cell component is recorded as integral component of plasma membrane[25].
  • NPC intracellular cholesterol transporter 1's cell component is recorded as extracellular region[26].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] . Q905695. Retrieved . wikidata.org.
  2. [3] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [4] . Retrieved . wikidata.org.
  4. [5] . wikidata.org.
  5. [6] . wikidata.org.
  6. [7] . wikidata.org.
  7. [8] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  8. [9] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  9. [10] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [11] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [12] . Niemann-Pick C1 protein: obligatory roles for N-terminal domains and lysosomal targeting in cholesterol mobilization. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [13] . NPC2 facilitates bidirectional transfer of cholesterol between NPC1 and lipid bilayers, a step in cholesterol egress from lysosomes. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] . Cholesterol depletion facilitates ubiquitylation of NPC1 and its association with SKD1/Vps4. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] . Mutations in NPC1 highlight a conserved NPC1-specific cysteine-rich domain. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] . Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] . Mutations in NPC1 highlight a conserved NPC1-specific cysteine-rich domain. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [23] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [24] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [25] . Q22254154. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [26] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). NPC intracellular cholesterol transporter 1. Retrieved May 3, 2026, from https://4ort.xyz/entity/npc-intracellular-cholesterol-transporter-1
MLA “NPC intracellular cholesterol transporter 1.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/npc-intracellular-cholesterol-transporter-1.
BibTeX @misc{4ortxyz_npc-intracellular-cholesterol-transporter-1_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{NPC intracellular cholesterol transporter 1}}, year = {2026}, url = {https://4ort.xyz/entity/npc-intracellular-cholesterol-transporter-1}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): NPC intracellular cholesterol transporter 1 — https://4ort.xyz/entity/npc-intracellular-cholesterol-transporter-1 (retrieved 2026-05-03)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 5w ago · Dirac · 2026-07-20 view diff on Wikidata ↗
    Commons category NPC1
    Molecular function virus receptor activity, lipid transporter activity, sterol transporter activity +4
    Uniprot protein id O15118
    Cell component integral component of membrane, vesicle, endosome +17
    + 15 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ [[Property:P18]]: Protein NPC1 PDB 3GKH.png, [[:toollabs:quickstatements/#/batch/261337|batch #261337]]"
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