Methylmalonyl-CoA mutase

mammalian protein found in Homo sapiens
Protein protein Q411008
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Methylmalonyl-CoA mutase

Summary

Methylmalonyl-CoA mutase is a protein[1]. It draws 62 Wikipedia views per month (protein category, ranking #130 of 987).[2]

Key Facts

  • Methylmalonyl-CoA mutase's instance of is recorded as protein[3].
  • Methylmalonyl-CoA mutase is part of Cobalamin-binding domain superfamily[4].
  • Methylmalonyl-CoA mutase is part of Cobalamin (vitamin B12)-dependent enzyme, catalytic[5].
  • Methylmalonyl-CoA mutase is part of Methylmalonyl-CoA mutase, C-terminal domain, protein family[6].
  • Methylmalonyl-CoA mutase is part of Methylmalonyl-CoA mutase, alpha/beta chain, catalytic domain, protein family[7].
  • Methylmalonyl-CoA mutase is part of Cobalamin (vitamin B12)-binding domain, protein family[8].
  • Methylmalonyl-CoA mutase is part of Methylmalonyl-CoA mutase, alpha chain, catalytic domain, protein family[9].
  • Methylmalonyl-CoA mutase comprises Cobalamin (vitamin B12)-binding domain[10].
  • Methylmalonyl-CoA mutase comprises Methylmalonyl-CoA mutase, C-terminal[11].
  • Methylmalonyl-CoA mutase comprises Methylmalonyl-CoA mutase, alpha chain, catalytic[12].
  • Methylmalonyl-CoA mutase comprises Methylmalonyl-CoA mutase, alpha/beta chain, catalytic[13].
  • Methylmalonyl-CoA mutase's molecular function is recorded as modified amino acid binding[14].
  • Methylmalonyl-CoA mutase's molecular function is recorded as isomerase activity[15].
  • Methylmalonyl-CoA mutase's molecular function is recorded as catalytic activity[16].
  • Methylmalonyl-CoA mutase's molecular function is recorded as metal ion binding[17].
  • Methylmalonyl-CoA mutase's molecular function is recorded as intramolecular transferase activity[18].
  • Methylmalonyl-CoA mutase's molecular function is recorded as methylmalonyl-CoA mutase activity[19].
  • Methylmalonyl-CoA mutase's molecular function is recorded as GTPase activity[20].
  • Methylmalonyl-CoA mutase's molecular function is recorded as protein binding[21].
  • Methylmalonyl-CoA mutase's molecular function is recorded as cobalamin binding[22].
  • Methylmalonyl-CoA mutase's molecular function is recorded as identical protein binding[23].
  • Methylmalonyl-CoA mutase's molecular function is recorded as protein homodimerization activity[24].
  • Methylmalonyl-CoA mutase's molecular function is recorded as methylmalonyl-CoA mutase activity[25].
  • Methylmalonyl-CoA mutase's cell component is recorded as mitochondrial matrix[26].
  • Methylmalonyl-CoA mutase's cell component is recorded as mitochondrion[27].

Why It Matters

Methylmalonyl-CoA mutase draws 62 Wikipedia views per month (protein category, ranking #130 of 987).[2] It has Wikipedia articles in 8 language editions, a strong signal of global cultural recognition.[28] It is known by 20 alternative names across languages and contexts.[29]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] . Q905695. Retrieved . wikidata.org.
  2. [4] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [5] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [6] . wikidata.org.
  5. [7] . wikidata.org.
  6. [8] . wikidata.org.
  7. [9] . wikidata.org.
  8. [10] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  9. [11] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  10. [12] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  11. [13] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  12. [14] . Novel associations of CPS1, MUT, NOX4, and DPEP1 with plasma homocysteine in a healthy population: a genome-wide evaluation of 13 974 participants in the Women's Genome Health Study. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [15] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] . Eight novel MUT loss-of-function missense mutations in Chinese patients with isolated methylmalonic academia. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] . Structures of the Human GTPase MMAA and Vitamin B 12 -dependent Methylmalonyl-CoA Mutase and Insight into Their Complex Formation. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] . Protein destabilization and loss of protein-protein interaction are fundamental mechanisms in cblA-type methylmalonic aciduria. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] . Structures of the Human GTPase MMAA and Vitamin B 12 -dependent Methylmalonyl-CoA Mutase and Insight into Their Complex Formation. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] . Structures of the Human GTPase MMAA and Vitamin B 12 -dependent Methylmalonyl-CoA Mutase and Insight into Their Complex Formation. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] . Molecular Genetic Characterization of 151 Mut-Type Methylmalonic Aciduria Patients and Identification of 41 Novel Mutations in MUT. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] . Cloning of full-length methylmalonyl-CoA mutase from a cDNA library using the polymerase chain reaction. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] . Wikimedia Foundation. dumps.wikimedia.org.
  2. [28] . Wikidata sitelinks. wikidata.org.
  3. [29] . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Methylmalonyl-CoA mutase. Retrieved May 3, 2026, from https://4ort.xyz/entity/methylmalonyl-coa-mutase
MLA “Methylmalonyl-CoA mutase.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/methylmalonyl-coa-mutase.
BibTeX @misc{4ortxyz_methylmalonyl-coa-mutase_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Methylmalonyl-CoA mutase}}, year = {2026}, url = {https://4ort.xyz/entity/methylmalonyl-coa-mutase}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Methylmalonyl-CoA mutase — https://4ort.xyz/entity/methylmalonyl-coa-mutase (retrieved 2026-05-03)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 5w ago · Boghog · 2026-07-23 view diff on Wikidata ↗
    Ec enzyme number 5.4.99.2
    "/* wbcreateclaim-create:1| */ [[Property:P591]]: 5.4.99.2, [[:toollabs:quickstatements/#/batch/261446|batch #261446]]"
  2. 5w ago · Dirac · 2026-07-20 view diff on Wikidata ↗
    Molecular function modified amino acid binding, isomerase activity, catalytic activity +9
    Part of
    Cell component mitochondrial matrix, mitochondrion
    Instance of protein
    + 9 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ [[Property:P18]]: Protein MUT PDB 2XIJ.png, [[:toollabs:quickstatements/#/batch/261337|batch #261337]]"
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