systemic lupus erythematosus

inflammation of connective tissue marked by skin rashes, joint pain and swelling, inflammation of the kidneys and inflammation of the tissue surrounding the heart.
MedicalCondition designated_intractable_rare_disease Q1485
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Summary

systemic lupus erythematosus is a designated intractable/rare disease[1]. It ranks in the top 4% of designated intractable rare disease entities by monthly Wikipedia readership (21,909 views/month).[2]

Key Facts

  • Instance of: rare disease[3], class of disease[4], symptom or sign[5]
  • Named after: Canis lupus[6]
  • Subclass of: rheumatism[7], lupus erythematosus[8], connective tissue disease[9], disease[10]
  • Commons category: Systemic lupus erythematosus[11]
  • ICPC 2 ID: L99[12]
  • Medical examination: Lupus band test[13]
  • External data available at URL: http://www.nanbyou.or.jp/entry/53[14]
  • Described by source: Brockhaus and Efron Encyclopedic Dictionary[15], The Nuttall Encyclopædia[16], Great Soviet Encyclopedia (1926–1947)[17]
  • ICD-9-CM: 710.0[18]
  • NCI Thesaurus ID: C3201[19]
  • Health specialty: immunology[20], rheumatology[21], dermatology[22]
  • Drug or therapy used for treatment: cyclosporine[23], azathioprine[24], hydroxychloroquine[25], (RS)-cyclophosphamide[26], triamcinolone[27], frentizole[28]
  • Genetic association: STAT4[29], TNPO3[30], MTG1[31], ITGAM[32], FCGR2A[33], CD80[34], CREBL2[35], GPR19[36], SLC29A3[37], SEZ6L2[38], DDA1[39], BANK1[40], TNFAIP3[41], TNIP1[42]

Why It Matters

systemic lupus erythematosus has Wikipedia articles in 29 language editions, a strong signal of global cultural recognition.[43] It is known by 68 alternative names across languages and contexts.[44]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . wikidata.org.
  2. [4] ↑ . wikidata.org.
  3. [5] ↑ . wikidata.org.
  4. [6] ↑ . wikidata.org.
  5. [7] ↑ . Disease Ontology. Retrieved . wikidata.org.
  6. [8] ↑ . Disease Ontology. Retrieved . wikidata.org.
  7. [9] ↑ . Disease Ontology. Retrieved . wikidata.org.
  8. [10] ↑ . wikidata.org.
  9. [11] ↑ . wikidata.org.
  10. [12] ↑ . wikidata.org.
  11. [13] ↑ . wikidata.org.
  12. [14] ↑ . ddrare.nibiohn.go.jp. Retrieved . ddrare.nibiohn.go.jp. Provenance: wikidata.org.
  13. [15] ↑ . wikidata.org.
  14. [16] ↑ . wikidata.org.
  15. [17] ↑ . wikidata.org.
  16. [18] ↑ . Disease Ontology. Retrieved . wikidata.org.
  17. [19] ↑ . Disease Ontology. Retrieved . wikidata.org.
  18. [20] ↑ . wikidata.org.
  19. [21] ↑ . wikidata.org.
  20. [22] ↑ . wikidata.org.
  21. [23] ↑ . NDF-RT. Retrieved . wikidata.org.
  22. [24] ↑ . NDF-RT. Retrieved . wikidata.org.
  23. [25] ↑ . NDF-RT. Retrieved . wikidata.org.
  24. [26] ↑ . NDF-RT. Retrieved . wikidata.org.
  25. [27] ↑ . NDF-RT. Retrieved . wikidata.org.
  26. [28] ↑ . Inxight: Drugs Database. Retrieved . drugs.ncats.io. Provenance: wikidata.org.
  27. [29] ↑ . Phenocarta. Retrieved . gemma.msl.ubc.ca. Provenance: wikidata.org.
  28. [30] ↑ . Phenocarta. Retrieved . gemma.msl.ubc.ca. Provenance: wikidata.org.
  29. [31] ↑ . Phenocarta. Retrieved . gemma.msl.ubc.ca. Provenance: wikidata.org.
  30. [32] ↑ . Phenocarta. Retrieved . gemma.msl.ubc.ca. Provenance: wikidata.org.
  31. [33] ↑ . Phenocarta. Retrieved . gemma.msl.ubc.ca. Provenance: wikidata.org.
  32. [34] ↑ . Phenocarta. Retrieved . gemma.msl.ubc.ca. Provenance: wikidata.org.
  33. [35] ↑ . Phenocarta. Retrieved . gemma.msl.ubc.ca. Provenance: wikidata.org.
  34. [36] ↑ . Phenocarta. Retrieved . gemma.msl.ubc.ca. Provenance: wikidata.org.
  35. [37] ↑ . Phenocarta. Retrieved . gemma.msl.ubc.ca. Provenance: wikidata.org.
  36. [38] ↑ . Phenocarta. Retrieved . gemma.msl.ubc.ca. Provenance: wikidata.org.
  37. [39] ↑ . Phenocarta. Retrieved . gemma.msl.ubc.ca. Provenance: wikidata.org.
  38. [40] ↑ . Phenocarta. Retrieved . gemma.msl.ubc.ca. Provenance: wikidata.org.
  39. [41] ↑ . Phenocarta. Retrieved . gemma.msl.ubc.ca. Provenance: wikidata.org.
  40. [42] ↑ . Phenocarta. Retrieved . gemma.msl.ubc.ca. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikimedia Foundation. dumps.wikimedia.org.
  2. [43] ↑ . Wikidata sitelinks. wikidata.org.
  3. [44] ↑ . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). systemic lupus erythematosus. Retrieved October 10, 2026, from https://4ort.xyz/entity/lupus
MLA “systemic lupus erythematosus.” 4ort.xyz Knowledge Graph, 4ort.xyz, 10 Oct. 2026, https://4ort.xyz/entity/lupus.
BibTeX @misc{4ortxyz_lupus_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{systemic lupus erythematosus}}, year = {2026}, url = {https://4ort.xyz/entity/lupus}, note = {Accessed: 2026-10-10}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): systemic lupus erythematosus — https://4ort.xyz/entity/lupus (retrieved 2026-10-10)

Canonical URL: https://4ort.xyz/entity/lupus · Last refreshed:

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 13w ago · Nyuhn · 2026-07-10 view diff on Wikidata ↗
    P14541 → 40VLYK
    "/* wbeditentity-update:0| */ QuickStatements 3.0 [[:toollabs:qs-dev/batch/40849|batch #40849]]: ZGBK ID"
  2. 14w ago · JhealdBatch bot · 2026-07-04 view diff on Wikidata ↗
    Subclass of → rheumatism, lupus erythematosus, connective tissue disease +1
    "/* wbeditentity-update:0| */ QuickStatements 3.0 [[:toollabs:qs-dev/batch/39915|batch #39915]]: rm redundant disease superclass"
  3. 14w ago · JhealdBatch bot · 2026-07-03 view diff on Wikidata ↗
    Subclass of → rheumatism, lupus erythematosus, connective tissue disease +1
    "/* wbeditentity-update:0| */ QuickStatements 3.0 [[:toollabs:qs-dev/batch/39732|batch #39732]]: rm redundant subclass"
  4. 20w ago · Twofivesixbot bot · 2026-05-22 view diff on Wikidata ↗
    Instance of → designated intractable/rare disease, rare disease, class of disease +1
    Risk factor → female
    Health specialty → immunology, rheumatology, dermatology
    Subclass of → rheumatism, lupus erythematosus, connective tissue disease +1
    + 11 other properties edited (see Wikidata diff for full list)
    "/* wbsetclaim-update-qualifiers:1||1|8 */ Yso id: 8745, mv to monolingual text names on YSO statements"
Live feed via Wikidata EventStreams. New edits appear within minutes of being made on Wikidata.