Insulin receptor related receptor

mammalian protein found in Homo sapiens

Protein protein Q21111104

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Insulin receptor related receptor

Summary

Insulin receptor related receptor is a protein^[1].

Key Facts

Insulin receptor related receptor's instance of is recorded as protein^[2].
Insulin receptor related receptor is part of Immunoglobulin-like fold^[3].
Insulin receptor related receptor is part of Protein kinase-like domain superfamily^[4].
Insulin receptor related receptor is part of Growth factor receptor cysteine-rich domain superfamily^[5].
Insulin receptor related receptor is part of Fibronectin type III superfamily^[6].
Insulin receptor related receptor is part of Insulin receptor-related protein^[7].
Insulin receptor related receptor is part of Receptor L-domain superfamily^[8].
Insulin receptor related receptor is part of Fibronectin type III, protein family^[9].
Insulin receptor related receptor is part of Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family^[10].
Insulin receptor related receptor is part of Receptor L-domain, protein family^[11].
Insulin receptor related receptor is part of Furin-like cysteine-rich domain, protein family^[12].
Insulin receptor related receptor is part of Protein kinase domain, protein family^[13].
Insulin receptor related receptor is part of Protein kinase, ATP binding site, protein family^[14].
Insulin receptor related receptor is part of Tyrosine-protein kinase, catalytic domain, protein family^[15].
Insulin receptor related receptor is part of Tyrosine-protein kinase, receptor class II, conserved site, protein family^[16].
Insulin receptor related receptor is part of Tyrosine-protein kinase, active site, protein family^[17].
Insulin receptor related receptor is part of Furin-like repeat, protein family^[18].
Insulin receptor related receptor comprises tyrosine-protein kinase, active site^[19].
Insulin receptor related receptor comprises protein kinase domain^[20].
Insulin receptor related receptor comprises serine-threonine/tyrosine-protein kinase, catalytic domain^[21].
Insulin receptor related receptor comprises Furin-like repeat^[22].
Insulin receptor related receptor comprises protein kinase, ATP binding site^[23].
Insulin receptor related receptor comprises Receptor L-domain^[24].
Insulin receptor related receptor comprises tyrosine-protein kinase, catalytic domain^[25].
Insulin receptor related receptor comprises Furin-like cysteine-rich domain^[26].

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Quick Facts

Instance of protein

Part of Immunoglobulin-like fold, Protein kinase-like domain superfamily, Growth factor receptor cysteine-rich domain superfamily, Fibronectin type III superfamily, Insulin receptor-related protein, Receptor L-domain superfamily, Fibronectin type III, protein family, Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family, Receptor L-domain, protein family, Furin-like cysteine-rich domain, protein family, Protein kinase domain, protein family, Protein kinase, ATP binding site, protein family, Tyrosine-protein kinase, catalytic domain, protein family, Tyrosine-protein kinase, receptor class II, conserved site, protein family, Tyrosine-protein kinase, active site, protein family, Furin-like repeat, protein family

Properties

Biological process actin cytoskeleton reorganization, protein autophosphorylation, protein phosphorylation, cellular response to alkaline pH, male sex determination, phosphorylation, transmembrane receptor protein tyrosine kinase signaling pathway, peptidyl-tyrosine phosphorylation, insulin receptor signaling pathway, negative regulation of signal transduction, cell differentiation, glucose homeostasis, negative regulation of apoptotic process, positive regulation of ERK1 and ERK2 cascade, transmembrane receptor protein tyrosine kinase signaling pathway, anatomical structure development

Cell component receptor complex, integral component of membrane, integral component of plasma membrane, membrane, cytoplasm, integral component of plasma membrane, insulin receptor complex, axon, receptor complex

Ec enzyme number 2.7.10.1

Encoded by INSRR

Found in taxon Homo sapiens

Has part(s) tyrosine-protein kinase, active site, protein kinase domain, serine-threonine/tyrosine-protein kinase, catalytic domain, Furin-like repeat, protein kinase, ATP binding site, Receptor L-domain, tyrosine-protein kinase, catalytic domain, Furin-like cysteine-rich domain, tyrosine-protein kinase, receptor class II, conserved site, fibronectin type III

Molecular function transmembrane receptor protein tyrosine kinase activity, phosphatidylinositol 3-kinase binding, insulin receptor substrate binding, nucleotide binding, protein kinase activity, protein tyrosine kinase activity, transferase activity, ATP binding, kinase activity, receptor tyrosine kinase, transmembrane signaling receptor activity, insulin-activated receptor activity, insulin receptor substrate binding, transmembrane receptor protein tyrosine kinase activity

External References (3)

Ensembl protein id ENSP00000357178

Refseq protein id NP_055030

Uniprot protein id P14616

🏷️ Also known as

en INSRR en insulin receptor-related protein en Insulin receptor related receptor en IR-related receptor

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Insulin receptor related receptor — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ Insulin receptor related receptor — part of (P361): Immunoglobulin-like fold. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[4] ↑ Insulin receptor related receptor — part of (P361): Protein kinase-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ Insulin receptor related receptor — part of (P361): Growth factor receptor cysteine-rich domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Insulin receptor related receptor — part of (P361): Fibronectin type III superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Insulin receptor related receptor — part of (P361): Insulin receptor-related protein. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Insulin receptor related receptor — part of (P361): Receptor L-domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[9] ↑ Insulin receptor related receptor — part of (P361): Fibronectin type III, protein family. wikidata.org.
[10] ↑ Insulin receptor related receptor — part of (P361): Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family. wikidata.org.
[11] ↑ Insulin receptor related receptor — part of (P361): Receptor L-domain, protein family. wikidata.org.
[12] ↑ Insulin receptor related receptor — part of (P361): Furin-like cysteine-rich domain, protein family. wikidata.org.
[13] ↑ Insulin receptor related receptor — part of (P361): Protein kinase domain, protein family. wikidata.org.
[14] ↑ Insulin receptor related receptor — part of (P361): Protein kinase, ATP binding site, protein family. wikidata.org.
[15] ↑ Insulin receptor related receptor — part of (P361): Tyrosine-protein kinase, catalytic domain, protein family. wikidata.org.
[16] ↑ Insulin receptor related receptor — part of (P361): Tyrosine-protein kinase, receptor class II, conserved site, protein family. wikidata.org.
[17] ↑ Insulin receptor related receptor — part of (P361): Tyrosine-protein kinase, active site, protein family. wikidata.org.
[18] ↑ Insulin receptor related receptor — part of (P361): Furin-like repeat, protein family. wikidata.org.
[19] ↑ Insulin receptor related receptor — has part(s) (P527): tyrosine-protein kinase, active site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ Insulin receptor related receptor — has part(s) (P527): protein kinase domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ Insulin receptor related receptor — has part(s) (P527): serine-threonine/tyrosine-protein kinase, catalytic domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ Insulin receptor related receptor — has part(s) (P527): Furin-like repeat. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ Insulin receptor related receptor — has part(s) (P527): protein kinase, ATP binding site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ Insulin receptor related receptor — has part(s) (P527): Receptor L-domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ Insulin receptor related receptor — has part(s) (P527): tyrosine-protein kinase, catalytic domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ Insulin receptor related receptor — has part(s) (P527): Furin-like cysteine-rich domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Insulin receptor related receptor is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). Insulin receptor related receptor. Retrieved May 3, 2026, from https://4ort.xyz/entity/insulin-receptor-related-receptor-q21111104

MLA

“Insulin receptor related receptor.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/insulin-receptor-related-receptor-q21111104.

BibTeX

@misc{4ortxyz_insulin-receptor-related-receptor-q21111104_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Insulin receptor related receptor}}, year = {2026}, url = {https://4ort.xyz/entity/insulin-receptor-related-receptor-q21111104}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Insulin receptor related receptor — https://4ort.xyz/entity/insulin-receptor-related-receptor-q21111104 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/insulin-receptor-related-receptor-q21111104 · Last refreshed: May 3, 2026

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

5w ago · Boghog · 2026-07-24 view diff on Wikidata ↗

Imported from → —

Encoded by → INSRR

Wikidata description → mammalian protein found in Homo sapiens

Molecular function → transmembrane receptor protein tyrosine kinase activity, phosphatidylinositol 3-kinase binding, insulin receptor substrate binding +11

+ 10 other properties edited (see Wikidata diff for full list)

"/* wbcreateclaim-create:1| */ [[Property:P591]]: 2.7.10.1, [[:toollabs:quickstatements/#/batch/261491|batch #261491]]"

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