IL2 inducible T cell kinase

mammalian protein found in Homo sapiens

Protein protein Q5974836

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IL2 inducible T cell kinase

Summary

IL2 inducible T cell kinase is a protein^[1].

Key Facts

IL2 inducible T cell kinase's instance of is recorded as protein^[2].
IL2 inducible T cell kinase's UniProt protein ID is recorded as Q08881^[3].
IL2 inducible T cell kinase's part of is recorded as SH3-like domain superfamily^[4].
IL2 inducible T cell kinase's part of is recorded as Protein kinase-like domain superfamily^[5].
IL2 inducible T cell kinase's part of is recorded as PH-like domain superfamily^[6].
IL2 inducible T cell kinase's part of is recorded as SH2 domain superfamily^[7].
IL2 inducible T cell kinase's part of is recorded as Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family^[8].
IL2 inducible T cell kinase's part of is recorded as pleckstrin homology domain, protein family^[9].
IL2 inducible T cell kinase's part of is recorded as SH2 domain, protein family^[10].
IL2 inducible T cell kinase's part of is recorded as SH3 domain, protein family^[11].
IL2 inducible T cell kinase's part of is recorded as Protein kinase domain, protein family^[12].
IL2 inducible T cell kinase's part of is recorded as Protein kinase, ATP binding site, protein family^[13].
IL2 inducible T cell kinase's part of is recorded as Tyrosine-protein kinase, catalytic domain, protein family^[14].
IL2 inducible T cell kinase's part of is recorded as Tyrosine-protein kinase, active site, protein family^[15].
IL2 inducible T cell kinase's part of is recorded as Tyrosine-protein kinase ITK, SH3 domain, protein family^[16].
IL2 inducible T cell kinase's part of is recorded as Zinc finger, Btk motif, protein family^[17].
IL2 inducible T cell kinase's has part is recorded as tyrosine-protein kinase, active site^[18].
IL2 inducible T cell kinase's has part is recorded as SH3 domain^[19].
IL2 inducible T cell kinase's has part is recorded as pleckstrin homology domain^[20].
IL2 inducible T cell kinase's has part is recorded as protein kinase, ATP binding site^[21].
IL2 inducible T cell kinase's has part is recorded as protein kinase domain^[22].
IL2 inducible T cell kinase's has part is recorded as tyrosine-protein kinase, catalytic domain^[23].
IL2 inducible T cell kinase's has part is recorded as SH2 domain^[24].
IL2 inducible T cell kinase's has part is recorded as serine-threonine/tyrosine-protein kinase, catalytic domain^[25].
IL2 inducible T cell kinase's has part is recorded as Zinc finger, Btk motif^[26].

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Quick Facts

Instance of protein

Part of SH3-like domain superfamily, Protein kinase-like domain superfamily, PH-like domain superfamily, SH2 domain superfamily, Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family, pleckstrin homology domain, protein family, SH2 domain, protein family, SH3 domain, protein family, Protein kinase domain, protein family, Protein kinase, ATP binding site, protein family, Tyrosine-protein kinase, catalytic domain, protein family, Tyrosine-protein kinase, active site, protein family, Tyrosine-protein kinase ITK, SH3 domain, protein family, Zinc finger, Btk motif, protein family

Properties

Biological process intracellular signal transduction, adaptive immune response, phosphorylation, NK T cell differentiation, transmembrane receptor protein tyrosine kinase signaling pathway, immune system process, cytokine production, activation of phospholipase C activity, Fc-epsilon receptor signaling pathway, protein phosphorylation, cellular defense response, regulation of cell population proliferation, peptidyl-tyrosine autophosphorylation, T cell receptor signaling pathway, T cell activation, signal transduction, interleukin-4 production, innate immune response, adaptive immune response, T cell receptor signaling pathway, B cell receptor signaling pathway

Cell component cytoplasm, cytosol, cell-cell junction, extrinsic component of cytoplasmic side of plasma membrane, nucleus

Encoded by ITK

Found in taxon Homo sapiens

Has part(s) tyrosine-protein kinase, active site, SH3 domain, pleckstrin homology domain, protein kinase, ATP binding site, protein kinase domain, tyrosine-protein kinase, catalytic domain, SH2 domain, serine-threonine/tyrosine-protein kinase, catalytic domain, Zinc finger, Btk motif, Tyrosine-protein kinase ITK, SH3 domain

Imported from wholeness_audit_2026-05-02

Molecular function transferase activity, nucleotide binding, protein kinase activity, non-membrane spanning protein tyrosine kinase activity, metal ion binding, kinase activity, protein binding, protein tyrosine kinase activity, signaling receptor binding, ATP binding, non-membrane spanning protein tyrosine kinase activity

External References (4)

Ensembl protein id ENSP00000398655, ENSP00000430327, ENSP00000431054

Pdb structure id 1SM2, 1SNU, 1SNX, 2E6I, 2LMJ, 2YUQ, 3MIY, 3MJ1, 3MJ2, 3QGW, 3QGY, 3T9T, 3V5J, 3V5L, 3V8T, 3V8W, 4HCT, 4HCU, 4HCV, 4KIO, 4L7S, 4M0Y, 4M0Z, 4M12, 4M13, 4M14, 4M15, 4MF0, 4MF1, 4PP9, 4PPA, 4PPB, 4PPC, 4PQN, 4QD6, 4RFM

Refseq protein id NP_005537, XP_016864932

Uniprot protein id Q08881

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ IL2 inducible T cell kinase — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ IL2 inducible T cell kinase — UniProt protein ID (P352): Q08881. Q905695. Retrieved 2019-11-13. wikidata.org.
[4] ↑ IL2 inducible T cell kinase — part of (P361): SH3-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ IL2 inducible T cell kinase — part of (P361): Protein kinase-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ IL2 inducible T cell kinase — part of (P361): PH-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ IL2 inducible T cell kinase — part of (P361): SH2 domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ IL2 inducible T cell kinase — part of (P361): Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family. wikidata.org.
[9] ↑ IL2 inducible T cell kinase — part of (P361): pleckstrin homology domain, protein family. wikidata.org.
[10] ↑ IL2 inducible T cell kinase — part of (P361): SH2 domain, protein family. wikidata.org.
[11] ↑ IL2 inducible T cell kinase — part of (P361): SH3 domain, protein family. wikidata.org.
[12] ↑ IL2 inducible T cell kinase — part of (P361): Protein kinase domain, protein family. wikidata.org.
[13] ↑ IL2 inducible T cell kinase — part of (P361): Protein kinase, ATP binding site, protein family. wikidata.org.
[14] ↑ IL2 inducible T cell kinase — part of (P361): Tyrosine-protein kinase, catalytic domain, protein family. wikidata.org.
[15] ↑ IL2 inducible T cell kinase — part of (P361): Tyrosine-protein kinase, active site, protein family. wikidata.org.
[16] ↑ IL2 inducible T cell kinase — part of (P361): Tyrosine-protein kinase ITK, SH3 domain, protein family. wikidata.org.
[17] ↑ IL2 inducible T cell kinase — part of (P361): Zinc finger, Btk motif, protein family. wikidata.org.
[18] ↑ IL2 inducible T cell kinase — has part(s) (P527): tyrosine-protein kinase, active site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ IL2 inducible T cell kinase — has part(s) (P527): SH3 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ IL2 inducible T cell kinase — has part(s) (P527): pleckstrin homology domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ IL2 inducible T cell kinase — has part(s) (P527): protein kinase, ATP binding site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ IL2 inducible T cell kinase — has part(s) (P527): protein kinase domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ IL2 inducible T cell kinase — has part(s) (P527): tyrosine-protein kinase, catalytic domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ IL2 inducible T cell kinase — has part(s) (P527): SH2 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ IL2 inducible T cell kinase — has part(s) (P527): serine-threonine/tyrosine-protein kinase, catalytic domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ IL2 inducible T cell kinase — has part(s) (P527): Zinc finger, Btk motif. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ IL2 inducible T cell kinase is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). IL2 inducible T cell kinase. Retrieved May 3, 2026, from https://4ort.xyz/entity/il2-inducible-t-cell-kinase

MLA

“IL2 inducible T cell kinase.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/il2-inducible-t-cell-kinase.

BibTeX

@misc{4ortxyz_il2-inducible-t-cell-kinase_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{IL2 inducible T cell kinase}}, year = {2026}, url = {https://4ort.xyz/entity/il2-inducible-t-cell-kinase}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): IL2 inducible T cell kinase — https://4ort.xyz/entity/il2-inducible-t-cell-kinase (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/il2-inducible-t-cell-kinase · Last refreshed: May 3, 2026