hydroxycarbamide
chemical compound
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Summary
hydroxycarbamide is a type of chemical entity[1]. hydroxycarbamide ranks in the top 5% of type of chemical entity entities by monthly Wikipedia readership (861 views/month).[2]
Key Facts
- Physically interacts with: Ribonucleotide reductase catalytic subunit M1[3], Ribonucleotide reductase regulatory subunit M2[4], Ribonucleotide reductase regulatory TP53 inducible subunit M2B[5]
- Canonical SMILES: C(=O)(N)NO[6]
- Chemical formula: CH₄N₂O₂[7]
- Subclass of: carbamide[8]
- Part of: response to hydroxyurea[9], cellular response to hydroxyurea[10]
- Has use: medication[11]
- Commons category: Hydroxyurea[12]
- Found in taxon: Streptomyces nigra[13]
- Mass: 76.027 dalton[14]
- Medical condition treated: head and neck cancer[15], Bellini duct carcinoma[16], ovarian cancer[17], uterine cancer[18], non-small-cell lung carcinoma[19], acropustulosis[20], brain cancer[21], essential thrombocytosis[22], prostate cancer[23], melanoma[24], hypereosinophilic syndrome[25], polycythemia vera[26], chronic myeloid leukemia[27], thrombogavitis[28]
- World Health Organisation international non-proprietary name: hydroxycarbamide[29]
- Subject has role: enzyme inhibitor[30], DNA polymerase inhibitors[31], antineoplastic[32], antisickling agents[33], essential medicine[34], developmental toxicant[35]
- Pregnancy category: Australian pregnancy category D[36], US pregnancy category D[37]
- Legal status (medicine): boxed warning[38]
- Active ingredient in: Siklos[39], Hydrea[40]
Why It Matters
hydroxycarbamide has Wikipedia articles in 24 language editions, a strong signal of global cultural recognition.[41] hydroxycarbamide is known by 39 alternative names across languages and contexts.[42]