fumarate hydratase

mammalian protein found in Homo sapiens
Protein protein Q21107515
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fumarate hydratase

Summary

fumarate hydratase is a protein[1]. It draws 76 Wikipedia views per month (protein category, ranking #130 of 987).[2]

Key Facts

  • fumarate hydratase's instance of is recorded as protein[3].
  • fumarate hydratase is part of Fumarase/histidase, N-terminal[4].
  • fumarate hydratase is part of L-Aspartase-like[5].
  • fumarate hydratase is part of Fumarate hydratase, class II[6].
  • fumarate hydratase is part of FH tetramer [mitochondrial matrix][7].
  • fumarate hydratase is part of Fumarase C, C-terminal domain, protein family[8].
  • fumarate hydratase is part of Fumarate lyase, N-terminal domain, protein family[9].
  • fumarate hydratase is part of Fumarate lyase, conserved site, protein family[10].
  • fumarate hydratase's Commons category is recorded as Fumarase[11].
  • fumarate hydratase comprises Fumarase C, C-terminal[12].
  • fumarate hydratase comprises Fumarate lyase, conserved site[13].
  • fumarate hydratase comprises Fumarate lyase, N-terminal[14].
  • fumarate hydratase's molecular function is recorded as protein binding[15].
  • fumarate hydratase's molecular function is recorded as catalytic activity[16].
  • fumarate hydratase's molecular function is recorded as lyase activity[17].
  • fumarate hydratase's molecular function is recorded as fumarate hydratase activity[18].
  • fumarate hydratase's molecular function is recorded as fumarate hydratase activity[19].
  • fumarate hydratase's cell component is recorded as cytoplasm[20].
  • fumarate hydratase's cell component is recorded as tricarboxylic acid cycle enzyme complex[21].
  • fumarate hydratase's cell component is recorded as mitochondrial matrix[22].
  • fumarate hydratase's cell component is recorded as extracellular exosome[23].
  • fumarate hydratase's cell component is recorded as mitochondrion[24].
  • fumarate hydratase's cell component is recorded as mitochondrion[25].
  • fumarate hydratase's cell component is recorded as extracellular exosome[26].
  • fumarate hydratase's biological process is recorded as homeostasis of number of cells within a tissue[27].

Why It Matters

fumarate hydratase draws 76 Wikipedia views per month (protein category, ranking #130 of 987).[2] It has Wikipedia articles in 17 language editions, a strong signal of global cultural recognition.[28] It is known by 8 alternative names across languages and contexts.[29]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] . Q905695. Retrieved . wikidata.org.
  2. [4] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [5] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [6] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [7] . wikidata.org.
  6. [8] . wikidata.org.
  7. [9] . wikidata.org.
  8. [10] . wikidata.org.
  9. [11] . wikidata.org.
  10. [12] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  11. [13] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  12. [14] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  13. [15] . Local generation of fumarate promotes DNA repair through inhibition of histone H3 demethylation. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] . Nucleotide sequence of a cDNA coding for mitochondrial fumarase from human liver. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] . Nucleotide sequence of a cDNA coding for mitochondrial fumarase from human liver. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] . Mutation of the fumarase gene in two siblings with progressive encephalopathy and fumarase deficiency. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] . MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] . Mutation of the fumarase gene in two siblings with progressive encephalopathy and fumarase deficiency. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] . Mutation of the fumarase gene in two siblings with progressive encephalopathy and fumarase deficiency. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] . MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] . Wikimedia Foundation. dumps.wikimedia.org.
  2. [28] . Wikidata sitelinks. wikidata.org.
  3. [29] . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). fumarate hydratase. Retrieved May 3, 2026, from https://4ort.xyz/entity/fumarate-hydratase
MLA “fumarate hydratase.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/fumarate-hydratase.
BibTeX @misc{4ortxyz_fumarate-hydratase_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{fumarate hydratase}}, year = {2026}, url = {https://4ort.xyz/entity/fumarate-hydratase}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): fumarate hydratase — https://4ort.xyz/entity/fumarate-hydratase (retrieved 2026-05-03)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 11h ago · Dirac · 2026-07-20 view diff on Wikidata ↗
    Molecular function protein binding, catalytic activity, lyase activity +2
    Part of
    Cell component cytoplasm, tricarboxylic acid cycle enzyme complex, mitochondrial matrix +4
    Instance of protein
    + 11 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ [[Property:P18]]: Fumarase 3e04.png, [[:toollabs:quickstatements/#/batch/261337|batch #261337]]"
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