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eplerenone

steroidal antimineralocorticoid of the spirolactone group that is used as an adjunct in the management of chronic heart failure
ChemicalSubstance type_of_chemical_entity Q423804
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Summary

eplerenone is a type of chemical entity[1]. eplerenone ranks in the top 5% of type of chemical entity entities by monthly Wikipedia readership (1,702 views/month).[2]

Key Facts

  • Canonical SMILES: CC12CCC(=O)C=C1CC(C3C24C(O4)CC5(C3CCC56CCC(=O)O6)C)C(=O)OC[3]
  • Chemical formula: C₂₄H₃₀O₆[4]
  • Subclass of: LSM-1524[5]
  • Has use: medication[6]
  • Commons category: Eplerenone[7]
  • Significant drug interaction: nabumetone[8], naproxen[9], celecoxib[10], Diclofenac[11], piroxicam[12], meloxicam[13], (RS)-fenoprofen[14], (±)-flurbiprofen[15], ibuprofen[16], (RS)-ketoprofen[17], (RS)-etodolac[18], sulindac[19], parecoxib[20], aceclofenac[21]

Why It Matters

eplerenone has Wikipedia articles in 15 language editions, a strong signal of global cultural recognition.[22] eplerenone is known by 13 alternative names across languages and contexts.[23]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . PubChem. Retrieved . wikidata.org.
  2. [4] ↑ . PubChem. Retrieved . wikidata.org.
  3. [5] ↑ . wikidata.org.
  4. [6] ↑ . wikidata.org.
  5. [7] ↑ . wikidata.org.
  6. [8] ↑ . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  7. [9] ↑ . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  8. [10] ↑ . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  9. [11] ↑ . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  10. [12] ↑ . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  11. [13] ↑ . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  12. [14] ↑ . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  13. [15] ↑ . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  14. [16] ↑ . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  15. [17] ↑ . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  16. [18] ↑ . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  17. [19] ↑ . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  18. [20] ↑ . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  19. [21] ↑ . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikimedia Foundation. dumps.wikimedia.org.
  2. [22] ↑ . Wikidata sitelinks. wikidata.org.
  3. [23] ↑ . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). eplerenone. Retrieved October 13, 2026, from https://4ort.xyz/entity/eplerenone
MLA “eplerenone.” 4ort.xyz Knowledge Graph, 4ort.xyz, 13 Oct. 2026, https://4ort.xyz/entity/eplerenone.
BibTeX @misc{4ortxyz_eplerenone_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{eplerenone}}, year = {2026}, url = {https://4ort.xyz/entity/eplerenone}, note = {Accessed: 2026-10-13}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): eplerenone — https://4ort.xyz/entity/eplerenone (retrieved 2026-10-13)

Canonical URL: https://4ort.xyz/entity/eplerenone · Last refreshed:

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 2d ago · VGMaintenanceBot bot · 2026-10-13 view diff on Wikidata ↗
    Significant drug interaction → nabumetone, naproxen, celecoxib +83
    Subject has role → antimineralocorticoid
    Subclass of → —
    Medical condition treated → arterial hypertension
    + 13 other properties edited (see Wikidata diff for full list)
    "/* wbsetqualifier-add:1| */ Mediawiki page id: 58991, Add qualifier to WikiProjectMed ID `Eplerenone`"
Live feed via Wikidata EventStreams. New edits appear within minutes of being made on Wikidata.