EPH receptor A2

mammalian protein found in Homo sapiens

Protein protein Q21114359

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EPH receptor A2

Summary

EPH receptor A2 is a protein^[1].

Key Facts

EPH receptor A2's instance of is recorded as protein^[2].
EPH receptor A2 is part of Immunoglobulin-like fold^[3].
EPH receptor A2 is part of Protein kinase-like domain superfamily^[4].
EPH receptor A2 is part of Fibronectin type III superfamily^[5].
EPH receptor A2 is part of ephrin receptor type-A /type-B^[6].
EPH receptor A2 is part of Galactose-binding-like domain superfamily^[7].
EPH receptor A2 is part of Growth factor receptor cysteine-rich domain superfamily^[8].
EPH receptor A2 is part of Sterile alpha motif/pointed domain superfamily^[9].
EPH receptor A2 is part of Fibronectin type III, protein family^[10].
EPH receptor A2 is part of Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family^[11].
EPH receptor A2 is part of ephrin receptor^[12].
EPH receptor A2 is part of Sterile alpha motif domain, protein family^[13].
EPH receptor A2 is part of Tyrosine-protein kinase ephrin type A/B receptor-like, protein family^[14].
EPH receptor A2 is part of Protein kinase domain, protein family^[15].
EPH receptor A2 is part of Ephrin type-A receptor 2, ligand binding domain, protein family^[16].
EPH receptor A2 is part of Tyrosine-protein kinase, receptor class V, conserved site, protein family^[17].
EPH receptor A2 is part of Protein kinase, ATP binding site, protein family^[18].
EPH receptor A2 is part of Tyrosine-protein kinase, catalytic domain, protein family^[19].
EPH receptor A2 is part of Ephrin receptor ligand binding domain, protein family^[20].
EPH receptor A2 is part of Tyrosine-protein kinase, active site, protein family^[21].
EPH receptor A2 comprises tyrosine-protein kinase, active site^[22].
EPH receptor A2 comprises protein kinase domain^[23].
EPH receptor A2 comprises serine-threonine/tyrosine-protein kinase, catalytic domain^[24].
EPH receptor A2 comprises protein kinase, ATP binding site^[25].
EPH receptor A2 comprises ephrin receptor ligand binding domain^[26].

⭐ Popularity Graph

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Quick Facts

Instance of protein

Part of Immunoglobulin-like fold, Protein kinase-like domain superfamily, Fibronectin type III superfamily, ephrin receptor type-A /type-B, Galactose-binding-like domain superfamily, Growth factor receptor cysteine-rich domain superfamily, Sterile alpha motif/pointed domain superfamily, Fibronectin type III, protein family, Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family, ephrin receptor, Sterile alpha motif domain, protein family, Tyrosine-protein kinase ephrin type A/B receptor-like, protein family, Protein kinase domain, protein family, Ephrin type-A receptor 2, ligand binding domain, protein family, Tyrosine-protein kinase, receptor class V, conserved site, protein family, Protein kinase, ATP binding site, protein family, Tyrosine-protein kinase, catalytic domain, protein family, Ephrin receptor ligand binding domain, protein family, Tyrosine-protein kinase, active site, protein family

Properties

Biological process regulation of lamellipodium assembly, skeletal system development, negative regulation of protein kinase B signaling, cell differentiation, regulation of cell adhesion mediated by integrin, protein kinase B signaling, activation of GTPase activity, phosphorylation, transmembrane receptor protein tyrosine kinase signaling pathway, keratinocyte differentiation, vasculogenesis, multicellular organism development, protein phosphorylation, cell adhesion, blood vessel development, notochord morphogenesis, notochord cell development, angiogenesis, intrinsic apoptotic signaling pathway in response to DNA damage, neural tube development, neuron differentiation, notochord, regulation of ERK1 and ERK2 cascade, cell chemotaxis, post-anal tail morphogenesis, axial mesoderm formation, response to growth factor, viral process, cell migration, apoptotic process, peptidyl-tyrosine phosphorylation, osteoclast differentiation, osteoblast differentiation, regulation of angiogenesis, regulation of blood vessel endothelial cell migration, ephrin receptor signaling pathway, lens fiber cell morphogenesis, mammary gland epithelial cell proliferation, bone remodeling, branching involved in mammary gland duct morphogenesis, negative regulation of cytokine production, defense response to Gram-positive bacterium, negative regulation of lymphangiogenesis, blood vessel endothelial cell proliferation involved in sprouting angiogenesis, pericyte cell differentiation, negative regulation of angiogenesis, inflammatory response, negative regulation of chemokine production, blood vessel morphogenesis, cAMP metabolic process, cell motility, viral entry into host cell, positive regulation of protein localization to plasma membrane, transmembrane receptor protein tyrosine kinase signaling pathway, axon guidance, protein localization to plasma membrane, positive regulation of bicellular tight junction assembly

Cell component integral component of membrane, cell projection, membrane, ruffle membrane, cell junction, lamellipodium membrane, leading edge membrane, focal adhesion, integral component of plasma membrane, intracellular anatomical structure, plasma membrane, lamellipodium, cell surface, integral component of plasma membrane, focal adhesion, cell surface, neuron projection, receptor complex, tight junctions

Ec enzyme number 2.7.10.1

Encoded by EPHA2

Exact match identifiers.org, purl.uniprot.org, www.ncbi.nlm.nih.gov

Found in taxon Homo sapiens

Has part(s) tyrosine-protein kinase, active site, protein kinase domain, serine-threonine/tyrosine-protein kinase, catalytic domain, protein kinase, ATP binding site, ephrin receptor ligand binding domain, tyrosine-protein kinase, receptor class V, conserved site, sterile alpha motif domain, tyrosine-protein kinase ephrin type A/B receptor-like, tyrosine-protein kinase, catalytic domain, Ephrin receptor, transmembrane domain, fibronectin type III, Ephrin type-A receptor 2, ligand binding domain

Molecular function nucleotide binding, protein kinase activity, transferase activity, kinase activity, protein binding, protein tyrosine kinase activity, ATP binding, ephrin receptor activity, transmembrane receptor protein tyrosine kinase activity, cadherin binding, virus receptor activity, transmembrane receptor protein tyrosine kinase activity, transmembrane-ephrin receptor activity, cadherin binding

External References (7)

Ensembl protein id ENSP00000351209

Mesh descriptor id D036104

Mesh tree code D08.811.913.696.620.682.725.400.850.100, D12.776.543.750.630.500.100, D12.776.476.568.400.850.100

Pdb structure id 1MQB, 2E8N, 2K9Y, 2KSO, 2X10, 2X11, 3C8X, 3CZU, 3FL7, 3HEI, 3HPN, 3KKA, 3MBW, 3MX0, 3SKJ, 4P2K, 4PDO, 4TRL, 5EK7

Refseq protein id NP_001316019, NP_004422, XP_016856026

Umls cui C0763620

Uniprot protein id P29317

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ EPH receptor A2 — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ EPH receptor A2 — part of (P361): Immunoglobulin-like fold. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[4] ↑ EPH receptor A2 — part of (P361): Protein kinase-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ EPH receptor A2 — part of (P361): Fibronectin type III superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ EPH receptor A2 — part of (P361): ephrin receptor type-A /type-B. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ EPH receptor A2 — part of (P361): Galactose-binding-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ EPH receptor A2 — part of (P361): Growth factor receptor cysteine-rich domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[9] ↑ EPH receptor A2 — part of (P361): Sterile alpha motif/pointed domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[10] ↑ EPH receptor A2 — part of (P361): Fibronectin type III, protein family. wikidata.org.
[11] ↑ EPH receptor A2 — part of (P361): Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family. wikidata.org.
[12] ↑ EPH receptor A2 — part of (P361): ephrin receptor. wikidata.org.
[13] ↑ EPH receptor A2 — part of (P361): Sterile alpha motif domain, protein family. wikidata.org.
[14] ↑ EPH receptor A2 — part of (P361): Tyrosine-protein kinase ephrin type A/B receptor-like, protein family. wikidata.org.
[15] ↑ EPH receptor A2 — part of (P361): Protein kinase domain, protein family. wikidata.org.
[16] ↑ EPH receptor A2 — part of (P361): Ephrin type-A receptor 2, ligand binding domain, protein family. wikidata.org.
[17] ↑ EPH receptor A2 — part of (P361): Tyrosine-protein kinase, receptor class V, conserved site, protein family. wikidata.org.
[18] ↑ EPH receptor A2 — part of (P361): Protein kinase, ATP binding site, protein family. wikidata.org.
[19] ↑ EPH receptor A2 — part of (P361): Tyrosine-protein kinase, catalytic domain, protein family. wikidata.org.
[20] ↑ EPH receptor A2 — part of (P361): Ephrin receptor ligand binding domain, protein family. wikidata.org.
[21] ↑ EPH receptor A2 — part of (P361): Tyrosine-protein kinase, active site, protein family. wikidata.org.
[22] ↑ EPH receptor A2 — has part(s) (P527): tyrosine-protein kinase, active site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ EPH receptor A2 — has part(s) (P527): protein kinase domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ EPH receptor A2 — has part(s) (P527): serine-threonine/tyrosine-protein kinase, catalytic domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ EPH receptor A2 — has part(s) (P527): protein kinase, ATP binding site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ EPH receptor A2 — has part(s) (P527): ephrin receptor ligand binding domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ EPH receptor A2 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). EPH receptor A2. Retrieved May 3, 2026, from https://4ort.xyz/entity/eph-receptor-a2

MLA “EPH receptor A2.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/eph-receptor-a2.

BibTeX

@misc{4ortxyz_eph-receptor-a2_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{EPH receptor A2}}, year = {2026}, url = {https://4ort.xyz/entity/eph-receptor-a2}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): EPH receptor A2 — https://4ort.xyz/entity/eph-receptor-a2 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/eph-receptor-a2 · Last refreshed: May 3, 2026

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

5d ago · Boghog · 2026-07-24 view diff on Wikidata ↗

Found in taxon → Homo sapiens

Mesh tree code → D08.811.913.696.620.682.725.400.850.100, D12.776.543.750.630.500.100, D12.776.476.568.400.850.100

Wikidata description → mammalian protein found in Homo sapiens

Pdb structure id → 1MQB, 2E8N, 2K9Y +16

+ 15 other properties edited (see Wikidata diff for full list)

"/* wbcreateclaim-create:1| */ [[Property:P591]]: 2.7.10.1, [[:toollabs:quickstatements/#/batch/261491|batch #261491]]"

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