Cyclin dependent kinase 8

mammalian protein found in Homo sapiens
Protein protein Q5198254
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Cyclin dependent kinase 8

Summary

Cyclin dependent kinase 8 is a protein[1].

Key Facts

  • Cyclin dependent kinase 8's instance of is recorded as protein[2].
  • Cyclin dependent kinase 8's physically interacts with is recorded as linifanib[3].
  • Cyclin dependent kinase 8's physically interacts with is recorded as ponatinib[4].
  • Cyclin dependent kinase 8's physically interacts with is recorded as sorafenib[5].
  • Cyclin dependent kinase 8 is part of Protein kinase-like domain superfamily[6].
  • Cyclin dependent kinase 8 is part of Protein kinase domain, protein family[7].
  • Cyclin dependent kinase 8 is part of Protein kinase, ATP binding site, protein family[8].
  • Cyclin dependent kinase 8 is part of Serine/threonine-protein kinase, active site, protein family[9].
  • Cyclin dependent kinase 8 comprises serine/threonine-protein kinase, active site[10].
  • Cyclin dependent kinase 8 comprises protein kinase, ATP binding site[11].
  • Cyclin dependent kinase 8 comprises protein kinase domain[12].
  • Cyclin dependent kinase 8's molecular function is recorded as transferase activity[13].
  • Cyclin dependent kinase 8's molecular function is recorded as protein kinase activity[14].
  • Cyclin dependent kinase 8's molecular function is recorded as nucleotide binding[15].
  • Cyclin dependent kinase 8's molecular function is recorded as kinase activity[16].
  • Cyclin dependent kinase 8's molecular function is recorded as protein binding[17].
  • Cyclin dependent kinase 8's molecular function is recorded as RNA polymerase II CTD heptapeptide repeat kinase activity[18].
  • Cyclin dependent kinase 8's molecular function is recorded as ATP binding[19].
  • Cyclin dependent kinase 8's molecular function is recorded as protein serine/threonine kinase activity[20].
  • Cyclin dependent kinase 8's molecular function is recorded as cyclin-dependent protein serine/threonine kinase activity[21].
  • Cyclin dependent kinase 8's molecular function is recorded as protein serine/threonine kinase activity[22].
  • Cyclin dependent kinase 8's cell component is recorded as mediator complex[23].
  • Cyclin dependent kinase 8's cell component is recorded as nucleoplasm[24].
  • Cyclin dependent kinase 8's cell component is recorded as nucleus[25].
  • Cyclin dependent kinase 8's cell component is recorded as nucleolus[26].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] . Q905695. Retrieved . wikidata.org.
  2. [3] . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  3. [4] . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  4. [5] . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  5. [6] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  6. [7] . wikidata.org.
  7. [8] . wikidata.org.
  8. [9] . wikidata.org.
  9. [10] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  10. [11] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  11. [12] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  12. [13] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] . Identification of human cyclin-dependent kinase 8, a putative protein kinase partner for cyclin C. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] . Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [23] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [24] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [25] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [26] . Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities.. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Cyclin dependent kinase 8. Retrieved May 3, 2026, from https://4ort.xyz/entity/cyclin-dependent-kinase-8
MLA “Cyclin dependent kinase 8.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/cyclin-dependent-kinase-8.
BibTeX @misc{4ortxyz_cyclin-dependent-kinase-8_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Cyclin dependent kinase 8}}, year = {2026}, url = {https://4ort.xyz/entity/cyclin-dependent-kinase-8}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Cyclin dependent kinase 8 — https://4ort.xyz/entity/cyclin-dependent-kinase-8 (retrieved 2026-05-03)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 4d ago · Boghog · 2026-07-23 view diff on Wikidata ↗
    Uniprot protein id P49336
    Umls cui C2720173
    Exact match http://purl.uniprot.org/uniprot/P49336
    Imported from
    + 17 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ [[Property:P591]]: 2.7.11.22, [[:toollabs:quickstatements/#/batch/261457|batch #261457]]"
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