checkpoint kinase 2

mammalian protein found in Homo sapiens
Protein protein Q5011104
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checkpoint kinase 2

Summary

checkpoint kinase 2 is a protein[1].

Key Facts

  • checkpoint kinase 2's instance of is recorded as protein[2].
  • checkpoint kinase 2 is part of Protein kinase-like domain superfamily[3].
  • checkpoint kinase 2 is part of SMAD/FHA domain superfamily[4].
  • checkpoint kinase 2 is part of Forkhead-associated (FHA) domain, protein family[5].
  • checkpoint kinase 2 is part of Protein kinase domain, protein family[6].
  • checkpoint kinase 2 is part of Serine/threonine-protein kinase, active site, protein family[7].
  • checkpoint kinase 2 comprises forkhead-associated (FHA) domain[8].
  • checkpoint kinase 2 comprises protein kinase domain[9].
  • checkpoint kinase 2 comprises serine/threonine-protein kinase, active site[10].
  • checkpoint kinase 2's molecular function is recorded as transferase activity[11].
  • checkpoint kinase 2's molecular function is recorded as nucleotide binding[12].
  • checkpoint kinase 2's molecular function is recorded as protein kinase activity[13].
  • checkpoint kinase 2's molecular function is recorded as protein homodimerization activity[14].
  • checkpoint kinase 2's molecular function is recorded as metal ion binding[15].
  • checkpoint kinase 2's molecular function is recorded as protein serine/threonine kinase activity[16].
  • checkpoint kinase 2's molecular function is recorded as protein binding[17].
  • checkpoint kinase 2's molecular function is recorded as identical protein binding[18].
  • checkpoint kinase 2's molecular function is recorded as protein kinase binding[19].
  • checkpoint kinase 2's molecular function is recorded as ATP binding[20].
  • checkpoint kinase 2's molecular function is recorded as ubiquitin protein ligase binding[21].
  • checkpoint kinase 2's molecular function is recorded as kinase activity[22].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] . Q905695. Retrieved . wikidata.org.
  2. [3] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [4] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [5] . wikidata.org.
  5. [6] . wikidata.org.
  6. [7] . wikidata.org.
  7. [8] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  8. [9] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  9. [10] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  10. [11] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [12] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [13] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] . Trans-activation of the DNA-damage signalling protein kinase Chk2 by T-loop exchange. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] . Linkage of ATM to cell cycle regulation by the Chk2 protein kinase. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] . Collaborator of ARF (CARF) regulates proliferative fate of human cells by dose-dependent regulation of DNA damage signaling. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] . Trans-activation of the DNA-damage signalling protein kinase Chk2 by T-loop exchange. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] . Priming phosphorylation of Chk2 by polo-like kinase 3 (Plk3) mediates its full activation by ATM and a downstream checkpoint in response to DNA damage. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] . The E3 ligase RNF8 regulates KU80 removal and NHEJ repair. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). checkpoint kinase 2. Retrieved May 3, 2026, from https://4ort.xyz/entity/checkpoint-kinase-2
MLA “checkpoint kinase 2.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/checkpoint-kinase-2.
BibTeX @misc{4ortxyz_checkpoint-kinase-2_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{checkpoint kinase 2}}, year = {2026}, url = {https://4ort.xyz/entity/checkpoint-kinase-2}, note = {Accessed: 2026-05-03}}
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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 1d ago · Boghog · 2026-07-23 view diff on Wikidata ↗
    Uniprot protein id O96017
    Umls cui C0296594
    Exact match http://purl.uniprot.org/uniprot/O96017
    Imported from
    + 17 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ [[Property:P591]]: 2.7.11.1, [[:toollabs:quickstatements/#/batch/261457|batch #261457]]"
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