Cell division cycle 42

mammalian protein found in Homo sapiens

Protein protein Q1198053

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Cell division cycle 42

Summary

Cell division cycle 42 is a protein^[1].

Key Facts

Cell division cycle 42's instance of is recorded as protein^[2].
Cell division cycle 42 is part of P-loop containing nucleoside triphosphate hydrolase^[3].
Cell division cycle 42 is part of cdc42^[4].
Cell division cycle 42 is part of Small GTP-binding protein domain family^[5].
Cell division cycle 42's Commons category is recorded as CDC42^[6].
Cell division cycle 42 comprises small GTP-binding protein domain^[7].
Cell division cycle 42's molecular function is recorded as Rho GDP-dissociation inhibitor binding^[8].
Cell division cycle 42's molecular function is recorded as ubiquitin protein ligase activity^[9].
Cell division cycle 42's molecular function is recorded as apolipoprotein A-I receptor binding^[10].
Cell division cycle 42's molecular function is recorded as GTP-dependent protein binding^[11].
Cell division cycle 42's molecular function is recorded as GTPase activity^[12].
Cell division cycle 42's molecular function is recorded as mitogen-activated protein kinase kinase kinase binding^[13].
Cell division cycle 42's molecular function is recorded as protein binding^[14].
Cell division cycle 42's molecular function is recorded as thioesterase binding^[15].
Cell division cycle 42's molecular function is recorded as protein kinase binding^[16].
Cell division cycle 42's molecular function is recorded as nucleotide binding^[17].
Cell division cycle 42's molecular function is recorded as GTP binding^[18].
Cell division cycle 42's molecular function is recorded as identical protein binding^[19].
Cell division cycle 42's molecular function is recorded as GTPase activity^[20].
Cell division cycle 42's molecular function is recorded as protein serine/threonine kinase activity^[21].
Cell division cycle 42's molecular function is recorded as GTP binding^[22].
Cell division cycle 42's molecular function is recorded as protein kinase binding^[23].
Cell division cycle 42's molecular function is recorded as GBD domain binding^[24].
Cell division cycle 42's cell component is recorded as cytoplasm^[25].
Cell division cycle 42's cell component is recorded as cytosol^[26].

⭐ Popularity Graph

1/100 established

Quick Facts

Instance of protein

Part of P-loop containing nucleoside triphosphate hydrolase, cdc42, Small GTP-binding protein domain family

Properties

Biological process cardiac conduction system development, positive regulation of protein phosphorylation, negative regulation of epidermal growth factor receptor signaling pathway, positive regulation of muscle cell differentiation, nuclear migration, keratinization, positive regulation of JNK cascade, establishment of Golgi localization, actin filament bundle assembly, positive regulation of neuron apoptotic process, vascular endothelial growth factor receptor signaling pathway, hair follicle morphogenesis, heart contraction, regulation of protein stability, neuron fate determination, substantia nigra development, Fc-gamma receptor signaling pathway involved in phagocytosis, actin filament organization, negative regulation of protein-containing complex assembly, epithelial-mesenchymal cell signaling, actin filament branching, negative regulation of gene expression, positive regulation of peptidyl-serine phosphorylation, establishment or maintenance of cell polarity, positive regulation of cell growth, regulation of protein metabolic process, establishment or maintenance of apical/basal cell polarity, regulation of protein kinase activity, regulation of attachment of spindle microtubules to kinetochore, regulation of small GTPase mediated signal transduction, positive regulation of hair follicle cell proliferation, positive regulation of MAPK cascade, regulation of mitotic nuclear division, hair follicle placode formation, positive regulation of intracellular protein transport, cell differentiation, positive regulation of epithelial cell proliferation involved in lung morphogenesis, regulation of protein heterodimerization activity, Golgi organization, positive regulation of synapse structural plasticity, multicellular organism growth, epidermis morphogenesis, nucleus localization, epithelial cell-cell adhesion, sprouting angiogenesis, nervous system development, macrophage differentiation, dendritic cell migration, positive regulation of cytokinesis, positive regulation of DNA replication, Wnt signaling pathway, planar cell polarity pathway, keratinocyte development, regulation of protein catabolic process, canonical Wnt signaling pathway, adherens junction organization, organelle transport along microtubule, actin cytoskeleton organization, regulation of filopodium assembly, endocytosis, ephrin receptor signaling pathway, filopodium assembly, T cell costimulation, blood coagulation, positive regulation of phosphatidylinositol 3-kinase activity, positive regulation of substrate adhesion-dependent cell spreading, positive regulation of gene expression, positive regulation of pseudopodium assembly, submandibular salivary gland formation, viral RNA genome replication, small GTPase mediated signal transduction, protein ubiquitination, positive regulation of catalytic activity, protein phosphorylation, endocytosis, phagocytosis, engulfment, actin filament organization, Golgi organization, establishment or maintenance of cell polarity, integrin-mediated signaling pathway, Rho protein signal transduction, regulation of cell shape, regulation of lamellipodium assembly, positive regulation of lamellipodium assembly, substantia nigra development, cell projection assembly, actin cytoskeleton organization, Cdc42 protein signal transduction, regulation of actin cytoskeleton organization, cell junction assembly, interleukin-12-mediated signaling pathway, neuropilin signaling pathway, establishment of epithelial cell apical/basal polarity, positive regulation of filopodium assembly, regulation of stress fiber assembly, positive regulation of stress fiber assembly, establishment of Golgi localization, dendritic spine morphogenesis, organelle transport along microtubule, modification of synaptic structure, positive regulation of actin cytoskeleton reorganization

Cell component cytoplasm, cytosol, membrane, cell-cell junction, focal adhesion, microtubule organizing center, spindle midzone, neuron projection, storage vacuole, cytoskeleton, cell projection, myelin sheath, extracellular exosome, filopodium, plasma membrane, spindle, apical part of cell, secretory granule, soma, cytoplasmic ribonucleoprotein granule, mitotic spindle, leading edge membrane, cell periphery, endoplasmic reticulum membrane, Golgi membrane, midbody, Golgi membrane, cytoplasm, centrosome, cytosol, plasma membrane, focal adhesion, cell cortex, membrane, Golgi transport complex, protein-containing complex, cell projection, neuron projection, dendritic spine, extracellular exosome

Ec enzyme number 3.6.5.2

Encoded by CDC42

Exact match identifiers.org, purl.uniprot.org, www.ncbi.nlm.nih.gov

Found in taxon Homo sapiens

Has part(s) small GTP-binding protein domain

Molecular function Rho GDP-dissociation inhibitor binding, ubiquitin protein ligase activity, apolipoprotein A-I receptor binding, GTP-dependent protein binding, GTPase activity, mitogen-activated protein kinase kinase kinase binding, protein binding, thioesterase binding, protein kinase binding, nucleotide binding, GTP binding, identical protein binding, GTPase activity, protein serine/threonine kinase activity, GTP binding, protein kinase binding, GBD domain binding

External References (4)

Ensembl protein id ENSP00000383118, ENSP00000314458, ENSP00000341072, ENSP00000398327, ENSP00000496911, ENSP00000498275, ENSP00000499132, ENSP00000497733, ENSP00000499473, ENSP00000499457, ENSP00000499612

Pdb structure id 4YDH, 1A4R, 1AJE, 1AM4, 1AN0, 1CEE, 1CF4, 1DOA, 1E0A, 1EES, 1GRN, 1GZS, 1KI1, 1KZ7, 1KZG, 1NF3, 2ASE, 2DFK, 2KB0, 2NGR, 2ODB, 2QRZ, 2WM9, 2WMN, 2WMO, 3GCG, 3QBV, 3VHL, 4DID, 4ITR, 4JS0, 4YC7, 5FI1

Refseq protein id NP_001034891, NP_001782, NP_426359

Uniprot protein id P60953

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Cell division cycle 42 — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ Cell division cycle 42 — part of (P361): P-loop containing nucleoside triphosphate hydrolase. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[4] ↑ Cell division cycle 42 — part of (P361): cdc42. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ Cell division cycle 42 — part of (P361): Small GTP-binding protein domain family. wikidata.org.
[6] ↑ Cell division cycle 42 — Commons category (P373): CDC42. wikidata.org.
[7] ↑ Cell division cycle 42 — has part(s) (P527): small GTP-binding protein domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Cell division cycle 42 — molecular function (P680): Rho GDP-dissociation inhibitor binding. GOA. Retrieved 2017-01-03. ebi.ac.uk. Provenance: wikidata.org.
[9] ↑ Cell division cycle 42 — molecular function (P680): ubiquitin protein ligase activity. Interaction of the Salmonella Typhimurium effector protein SopB with host cell Cdc42 is involved in intracellular replication. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[10] ↑ Cell division cycle 42 — molecular function (P680): apolipoprotein A-I receptor binding. Apolipoprotein A-I activates Cdc42 signaling through the ABCA1 transporter. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[11] ↑ Cell division cycle 42 — molecular function (P680): GTP-dependent protein binding. GOA. Retrieved 2017-01-03. ebi.ac.uk. Provenance: wikidata.org.
[12] ↑ Cell division cycle 42 — molecular function (P680): GTPase activity. A new family of Cdc42 effector proteins, CEPs, function in fibroblast and epithelial cell shape changes. Retrieved 2017-01-03. ebi.ac.uk. Provenance: wikidata.org.
[13] ↑ Cell division cycle 42 — molecular function (P680): mitogen-activated protein kinase kinase kinase binding. GOA. Retrieved 2017-01-03. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ Cell division cycle 42 — molecular function (P680): protein binding. Role of RacC for the regulation of WASP and phosphatidylinositol 3-kinase during chemotaxis of Dictyostelium. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ Cell division cycle 42 — molecular function (P680): thioesterase binding. The TRE17 oncogene encodes a component of a novel effector pathway for Rho GTPases Cdc42 and Rac1 and stimulates actin remodeling. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ Cell division cycle 42 — molecular function (P680): protein kinase binding. ARHGEF7 (Beta-PIX) acts as guanine nucleotide exchange factor for leucine-rich repeat kinase 2. Retrieved 2017-01-03. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Cell division cycle 42 — molecular function (P680): nucleotide binding. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Cell division cycle 42 — molecular function (P680): GTP binding. GOA. Retrieved 2017-01-03. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ Cell division cycle 42 — molecular function (P680): identical protein binding. Negative Regulation of Rho Family GTPases Cdc42 and Rac2 by Homodimer Formation. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ Cell division cycle 42 — molecular function (P680): GTPase activity. A new family of Cdc42 effector proteins, CEPs, function in fibroblast and epithelial cell shape changes. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ Cell division cycle 42 — molecular function (P680): protein serine/threonine kinase activity. GOA. Retrieved 2018-01-01. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ Cell division cycle 42 — molecular function (P680): GTP binding. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ Cell division cycle 42 — molecular function (P680): protein kinase binding. Characterization of hNek6 interactome reveals an important role for its short N-terminal domain and colocalization with proteins at the centrosome. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ Cell division cycle 42 — molecular function (P680): GBD domain binding. Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ Cell division cycle 42 — cell component (P681): cytoplasm. GOA. Retrieved 2017-01-03. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ Cell division cycle 42 — cell component (P681): cytosol. GOA. Retrieved 2017-01-03. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Cell division cycle 42 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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APA

4ort.xyz Knowledge Graph. (2026). Cell division cycle 42. Retrieved May 3, 2026, from https://4ort.xyz/entity/cell-division-cycle-42

MLA

“Cell division cycle 42.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/cell-division-cycle-42.

BibTeX

@misc{4ortxyz_cell-division-cycle-42_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Cell division cycle 42}}, year = {2026}, url = {https://4ort.xyz/entity/cell-division-cycle-42}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Cell division cycle 42 — https://4ort.xyz/entity/cell-division-cycle-42 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/cell-division-cycle-42 · Last refreshed: May 3, 2026

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

10d ago · Boghog · 2026-07-22 view diff on Wikidata ↗

Uniprot protein id → P60953

Exact match → https://identifiers.org/uniprot:P60953, http://purl.uniprot.org/uniprot/P60953, https://www.ncbi.nlm.nih.gov/protein/P60953

Imported from → —

Ensembl protein id → ENSP00000383118, ENSP00000314458, ENSP00000341072 +8

+ 14 other properties edited (see Wikidata diff for full list)

"/* wbcreateclaim-create:1| */ [[Property:P591]]: 3.6.5.2, #quickstatements; #temporary_batch_1784744182951"

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