arginine vasopressin

hormone synthesized from the AVP gene as a peptide prohormone in neurons in the hypothalamus, and is converted to AVP
Protein protein Q21124841
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Summary

arginine vasopressin is a protein[1]. It ranks in the top 0.2% of protein entities by monthly Wikipedia readership (4,809 views/month, #2 of 987).[2]

Key Facts

  • Instance of: vasopressin[3], peptide hormone[4]
  • Part of: Neurohypophysial hormone[5], Neurohypophysial hormone domain superfamily[6], Neurohypophysial hormone, conserved site, protein family[7]
  • Commons category: Vasopressin[8]
  • Has part(s): Neurohypophysial hormone, conserved site[9], copeptin[10]
  • Molecular function: protein kinase activity[11], hormone activity[12], cysteine-type endopeptidase inhibitor activity involved in apoptotic process[13], neurohypophyseal hormone activity[14], signaling receptor binding[15], V1A vasopressin receptor binding[16], V1B vasopressin receptor binding[17], neuropeptide hormone activity[18]
  • Cell component: extracellular region[19], cytosol[20], clathrin-coated vesicle membrane[21], extracellular space[22], secretory granule[23], dendrite[24]
  • Biological process: negative regulation of cysteine-type endopeptidase activity involved in apoptotic process[25], vasoconstriction[26], negative regulation of release of cytochrome c from mitochondria[27], ERK1 and ERK2 cascade[28], water transport[29], cell-cell signaling[30], negative regulation of apoptotic process[31], protein kinase C signaling[32], generation of precursor metabolites and energy[33], positive regulation of peptidyl-serine phosphorylation[34], positive regulation of gene expression[35], renal water homeostasis[36], signal transduction[37], apoptotic process[38]

Why It Matters

arginine vasopressin has Wikipedia articles in 28 language editions, a strong signal of global cultural recognition.[39] It is known by 41 alternative names across languages and contexts.[40]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . wikidata.org.
  2. [4] ↑ . wikidata.org.
  3. [5] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [6] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [7] ↑ . wikidata.org.
  6. [8] ↑ . wikidata.org.
  7. [9] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  8. [10] ↑ . wikidata.org.
  9. [11] ↑ . Anti-apoptotic actions of vasopressin in H32 neurons involve MAP kinase transactivation and Bad phosphorylation. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [12] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [13] ↑ . Anti-apoptotic actions of vasopressin in H32 neurons involve MAP kinase transactivation and Bad phosphorylation. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [14] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [15] ↑ . A fully active nonglycosylated V2 vasopressin receptor. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] ↑ . Anti-apoptotic actions of vasopressin in H32 neurons involve MAP kinase transactivation and Bad phosphorylation. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] ↑ . A missense mutation in the vasopressin-neurophysin precursor gene cosegregates with human autosomal dominant neurohypophyseal diabetes insipidus. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] ↑ . Anti-apoptotic actions of vasopressin in H32 neurons involve MAP kinase transactivation and Bad phosphorylation. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] ↑ . Anti-apoptotic actions of vasopressin in H32 neurons involve MAP kinase transactivation and Bad phosphorylation. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  26. [28] ↑ . Anti-apoptotic actions of vasopressin in H32 neurons involve MAP kinase transactivation and Bad phosphorylation. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  27. [29] ↑ . A missense mutation in the vasopressin-neurophysin precursor gene cosegregates with human autosomal dominant neurohypophyseal diabetes insipidus. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  28. [30] ↑ . A missense mutation in the vasopressin-neurophysin precursor gene cosegregates with human autosomal dominant neurohypophyseal diabetes insipidus. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  29. [31] ↑ . Anti-apoptotic actions of vasopressin in H32 neurons involve MAP kinase transactivation and Bad phosphorylation. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  30. [32] ↑ . Anti-apoptotic actions of vasopressin in H32 neurons involve MAP kinase transactivation and Bad phosphorylation. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  31. [33] ↑ . A missense mutation in the vasopressin-neurophysin precursor gene cosegregates with human autosomal dominant neurohypophyseal diabetes insipidus. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  32. [34] ↑ . Anti-apoptotic actions of vasopressin in H32 neurons involve MAP kinase transactivation and Bad phosphorylation. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  33. [35] ↑ . AQP1 gene expression is upregulated by arginine vasopressin and cyclic AMP agonists in trophoblast cells. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  34. [36] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  35. [37] ↑ . A fully active nonglycosylated V2 vasopressin receptor. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  36. [38] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikimedia Foundation. dumps.wikimedia.org.
  2. [39] ↑ . Wikidata sitelinks. wikidata.org.
  3. [40] ↑ . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). arginine vasopressin. Retrieved October 17, 2026, from https://4ort.xyz/entity/arginine-vasopressin
MLA “arginine vasopressin.” 4ort.xyz Knowledge Graph, 4ort.xyz, 17 Oct. 2026, https://4ort.xyz/entity/arginine-vasopressin.
BibTeX @misc{4ortxyz_arginine-vasopressin_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{arginine vasopressin}}, year = {2026}, url = {https://4ort.xyz/entity/arginine-vasopressin}, note = {Accessed: 2026-10-17}}
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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 13w ago · Dirac · 2026-07-20 view diff on Wikidata ↗
    Image → Vasopressin structure.png
    "/* wbcreateclaim-create:1| */ Image: Vasopressin structure.png, [[:toollabs:quickstatements/#/batch/261337|batch #261337]]"
  2. 22w ago · BorkedBot bot · 2026-05-16 view diff on Wikidata ↗
    Lex id → ADH
    "/* wbsetqualifier-add:1| */ Subject named as: Vasopressin, update metadata from fandom API ([[:toolforge:editgroups/b/CB/c89789be56bd|details]])"
  3. 24w ago · Tunyk · 2026-04-30 view diff on Wikidata ↗
    Kegg id → K05242
    Mesh descriptor id → D001127
    Found in taxon → Homo sapiens
    Has part(s) → Neurohypophysial hormone, conserved site, copeptin
    + 17 other properties edited (see Wikidata diff for full list)
    "/* wbsetclaim-create:2||1 */ Mesh descriptor id: D001127"
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