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Alpha-2-macroglobulin

mammalian protein found in Homo sapiens
Protein protein Q22680187
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Alpha-2-macroglobulin

Summary

Alpha-2-macroglobulin is a protein[1]. Alpha-2-macroglobulin has Wikipedia articles in 11 language editions, a strong signal of global cultural recognition.[2]

Key Facts

  • Alpha-2-macroglobulin's instance of is recorded as protein[3].
  • Alpha-2-macroglobulin is a type of protein[4].
  • Alpha-2-macroglobulin is a type of alpha globulin[5].
  • Alpha-2-macroglobulin is part of Immunoglobulin-like fold[6].
  • Alpha-2-macroglobulin is part of Alpha-macroglobulin, receptor-binding domain superfamily[7].
  • Alpha-2-macroglobulin is part of Immunoglobulin E-set[8].
  • Alpha-2-macroglobulin is part of Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid[9].
  • Alpha-2-macroglobulin is part of Alpha-2-macroglobulin, protein family[10].
  • Alpha-2-macroglobulin is part of Alpha-macroglobulin, receptor-binding domain, protein family[11].
  • Alpha-2-macroglobulin is part of Macroglobulin domain, protein family[12].
  • Alpha-2-macroglobulin is part of Alpha-2-macroglobulin, bait region domain, protein family[13].
  • Alpha-2-macroglobulin is part of Alpha-macroglobulin, TED domain, protein family[14].
  • Alpha-2-macroglobulin is part of Alpha-2-macroglobulin, conserved site, protein family[15].
  • Alpha-2-macroglobulin is part of TonB box, conserved site, protein family[16].
  • Alpha-2-macroglobulin comprises Alpha-macroglobulin, TED domain[17].
  • Alpha-2-macroglobulin comprises Alpha-2-macroglobulin[18].
  • Alpha-2-macroglobulin comprises TonB box, conserved site[19].
  • Alpha-2-macroglobulin comprises Alpha-2-macroglobulin, bait region domain[20].
  • Alpha-2-macroglobulin comprises Macroglobulin domain[21].
  • Alpha-2-macroglobulin comprises Alpha-2-macroglobulin, conserved site[22].
  • Alpha-2-macroglobulin comprises Alpha-macroglobulin, receptor-binding[23].
  • Alpha-2-macroglobulin's molecular function is recorded as peptidase inhibitor activity[24].
  • Alpha-2-macroglobulin's molecular function is recorded as interleukin-8 binding[25].
  • Alpha-2-macroglobulin's molecular function is recorded as growth factor binding[26].
  • Alpha-2-macroglobulin's molecular function is recorded as calcium-dependent protein binding[27].

Why It Matters

Alpha-2-macroglobulin has Wikipedia articles in 11 language editions, a strong signal of global cultural recognition.[2] Alpha-2-macroglobulin is known by 7 alternative names across languages and contexts.[28]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . Q905695. Retrieved . wikidata.org.
  2. [4] ↑ . Q905695. Retrieved . wikidata.org.
  3. [5] ↑ . wikidata.org.
  4. [6] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [7] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  6. [8] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  7. [9] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  8. [10] ↑ . wikidata.org.
  9. [11] ↑ . wikidata.org.
  10. [12] ↑ . wikidata.org.
  11. [13] ↑ . wikidata.org.
  12. [14] ↑ . wikidata.org.
  13. [15] ↑ . wikidata.org.
  14. [16] ↑ . wikidata.org.
  15. [17] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  16. [18] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  17. [19] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  18. [20] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  19. [21] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  20. [22] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  21. [23] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  22. [24] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] ↑ . Involvement of alpha-2-macroglobulin receptor in clearance of interleukin 8-alpha-2-macroglobulin complexes by human alveolar macrophages. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] ↑ . Human α2-Macroglobulin Is an Osteogenic Growth Peptide-Binding Protein. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] ↑ . Identification and characterization of the acidic pH binding sites for growth regulatory ligands of low density lipoprotein receptor-related protein-1. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikidata sitelinks. wikidata.org.
  2. [28] ↑ . Wikidata aliases. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Alpha-2-macroglobulin. Retrieved May 3, 2026, from https://4ort.xyz/entity/alpha-2-macroglobulin
MLA “Alpha-2-macroglobulin.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/alpha-2-macroglobulin.
BibTeX @misc{4ortxyz_alpha-2-macroglobulin_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Alpha-2-macroglobulin}}, year = {2026}, url = {https://4ort.xyz/entity/alpha-2-macroglobulin}, note = {Accessed: 2026-05-03}}
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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 2d ago · Dirac · 2026-07-20 view diff on Wikidata ↗
    Molecular function → peptidase inhibitor activity, interleukin-8 binding, growth factor binding +12
    Subclass of → —
    Part of → —
    Cell component → cytosol, blood microparticle, extracellular region +7
    + 11 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ [[Property:P18]]: Crystal structure of alpha-2-macroglobulin.png, [[:toollabs:quickstatements/#/batch/261337|batch #261337]]"
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